12 Fascinating Facts About Ivan Pavlov

Wikimedia Commons // Public Domain
Wikimedia Commons // Public Domain

Thanks to Ivan Pavlov, we’re all familiar with classical conditioning and the Pavlovian response (ring a bell before giving a dog a plate of food enough times, and he'll eventually begin to salivate at the sound of the bell rather than the sight of the meal). But if you want to know more about the man himself, from his side gig selling canine gastric juice to his couch-surfing days, it's time to examine these 12 drool-worthy facts about Ivan Pavlov.

1. A LOT OF WHAT WE THINK WE KNOW ABOUT HIM IS WRONG.

Pavlov’s biographers point out that most people have misconceptions about the Russian physiologist. For example, instead of ringing a bell to train dogs, Pavlov actually used a variety of tools such as a metronome, buzzer, whistle, light, harmonium, and even electric shock. And Pavlov’s concept of the conditioned response is, in reality, not exactly what he pioneered. He discussed the conditional response, but a mistranslation of the original Russian word uslovnyi gave us the phrase conditioned response, which is still used today.

2. HE PLANNED TO BECOME A PRIEST.

Pavlov was born in Ryazan, Russia in 1849. His father was a priest, and Pavlov enrolled in a theological seminary. But after reading the works of Russian physiologist Ivan Sechenov, Pavlov decided to change course. In 1870, he left the seminary and enrolled at what is now known as St. Petersburg University to study natural science, physics, and math.

3. HIS CHEMISTRY PROFESSOR WAS A BIG DEAL.

During Pavlov’s first year of university, one of the classes he took was inorganic chemistry. His professor, Dmitri Mendeleev, was a big deal in the world of science. In 1869, Mendeleev published the first periodic table of elements and is credited as the father of the periodic table. Not too shabby.

4. HIS EARLY WORK DEALT WITH PANCREATIC NERVES AND ANIMAL DIGESTION.


Wikimedia Commons

Throughout the 1870s and early 1880s, Pavlov studied the natural sciences and physiology, conducting research and working on his doctorate thesis. Specifically, he wrote about the function of the nerves in the pancreas and the heart. In 1890, Pavlov was asked to develop and direct a physiology department at the Institute of Experimental Medicine, where he studied the interplay between the nervous system and digestion.

5. HE WAS SO POOR THAT HE COUCH-SURFED FOR A FEW MONTHS.

Russian scientists worked in modest labs and were paid very little, so Pavlov struggled with finances. In 1887 he couldn’t afford his apartment anymore, so he spent a few months away from his wife Serafima (or Seraphima) Karchevskaya and young son. Pavlov crashed with friends or slept in his lab, and he took on extra jobs; he taught physiology and worked on a medical journal to earn more money.

6. HE FINANCED HIS LAB BY SELLING CANINE GASTRIC JUICE AS A CURE FOR INDIGESTION.

Pavlov kept his physiology lab running by selling something that he had easy access to: canine gastric juice. While conducting experiments on dogs’ digestive systems, Pavlov collected gastric juice from hungry dogs that stared at a big bowl of meat all day. Pavlov paid an assistant to run the gastric juice collection operation, and he sold thousands of containers of the juice each year to people around Europe, who drank it daily to treat dyspepsia (indigestion). Yum!

7. AFTER HIS FIRST SON DIED, HE NAMED ALL HIS FUTURE CHILDREN WITH “V” NAMES.

If you think Pavlov and the Kardashians have nothing in common, think again. After the sudden death of their first child, Wirchik, at a very young age, the Pavlovs had four more children: three sons and a daughter, whom they named Vladimir, Victor, Vsevolod, and Vera.

8. HE WON A NOBEL PRIZE FOR REMOVING DOGS’ ESOPHAGI.

Ivan Pavlov with students
Wellcome Images Gallery, Wikimedia Commons // CC BY 4.0

Although Pavlov’s best-known work—showing how an environmental stimulus can influence a behavioral response—was groundbreaking, he won a Nobel Prize in 1904 for something different. He earned the honor for his research into the animal digestive system. After surgically removing a dog’s esophagus, Pavlov fed the animal and observed how the process of digestion worked, measuring the digestive secretions of the stomach and pancreas.

9. H.G. WELLS WROTE ABOUT PAVLOV FOR THE NEW YORK TIMES MAGAZINE.

In November 1927, science fiction writer H.G. Wells wrote an essay about Pavlov for The New York Times Magazine. Because Wells didn’t fully understand the science behind one of Pavlov’s articles about reflexes, he ignored the heavy-duty science and focused on Pavlov the man. Wells wrote about Pavlov’s "vastly heroic" nature and devotion to advancing science in the face of poverty, war, and revolution. After a 23-year-old B.F. Skinner read Wells’s article on Pavlov, he became a fan and grew up to be one of history’s most influential behavioral psychologists.

10. HE HAD A BAD TEMPER.

Ivan Pavlov
Wikimedia Commons

According to his biographer, Daniel Todes, Pavlov had issues with anger management. Beginning in childhood, his mood could change suddenly, and as an adult, he hit aggressive dogs in his lab and was known for his uncontrollable outbursts of anger. Pavlov himself described his angry outbursts as “morbid, spontaneous paroxysms.”

11. HE SPOKE OUT AGAINST SOVIET COMMUNISM.

In 1921, Vladimir Lenin publicly praised Pavlov for his scientific contributions, and the Soviet government funded his research and offered him increased food rations (he didn’t accept). But Pavlov spoke out against communism, requesting in 1922 that he be allowed to move his lab to another country. Lenin refused. Pavlov said, “For the kind of social experiment that you are making, I would not sacrifice a frog’s hind legs!” Pavlov also decried his government’s persecution of political dissidents and clergymen; in a letter, Pavlov told Joseph Stalin that he was "ashamed to be called a Russian." Pavlov wasn’t killed for his contrarian views because the government determined that his scientific work was too valuable for Russia.

12. HIS HOME AND APARTMENT WERE CONVERTED TO MEMORIAL MUSEUMS.

Pavlov’s estate in Ryazan, Russia is now a museum where visitors can explore his life and achievements. If you visit, be prepared to see stuffed dogs (and even a monkey) that Pavlov used in his experiments. And if you find yourself in St. Petersburg, you can check out The Pavlov Memorial Museum, where Pavlov lived for almost two decades before he died on February 27, 1936.

Chronic Pain Happens Differently in Men and Women

iStock.com/PeopleImages
iStock.com/PeopleImages

Women often feel colder than men due to physical differences. Now, a new study shows that the two sexes have different biological processes underlying a specific kind of pain, too. As WIRED reports, research published in the journal Brain revealed that different cells and proteins were activated in men and women with neuropathic pain—a condition that is often chronic, with symptoms including a burning or shooting sensation. While scientists say further research is needed, these findings could potentially change the way we treat conditions involving chronic pain.

A team of Texas-based neurologists and neuroscientists looked for RNA expressions in the sensory neurons of spinal tumors that had been removed from eight women and 18 men. Some of the patients had pain as a result of nerve compression, while others had not experienced any chronic pain. While studying the neurons of women with pain, researchers noticed that protein-like molecules called neuropeptides, which modulate neurons, were highly activated. For the men, immune system cells called macrophages were most active.

"This represents the first direct human evidence that pain seems to be as sex-dependent in its underlying biology in humans as we have been suggesting for a while now, based on experiments in mice," Jeffrey Mogil, a professor of pain studies at Montreal's McGill University, who was not involved in the Brain study, tells WIRED.

So what exactly do these new findings mean for sufferers of chronic pain? Considering that clinical trials and drug manufacturers have traditionally failed to distinguish between the sexes when it comes to developing pain medication, the study could potentially form a foundation for sex-specific pain therapies that could prove more effective. This might be especially promising for women, who are more likely to have some condition that cause persistent pain, such as migraines or fibromyalgia.

"I think that 10 years from now, when I look back at how papers I've published have had an impact, this one will stick out," Dr. Ted Price, a neuroscience professor and one of the paper's authors, said in a statement. "I hope by then that we are designing clinical trials better considering sex as a biological variable, and that we understand how chronic pain is driven differently in men and women."

[h/t WIRED]

For the First Time Ever, a Woman Has Won the Abel Prize—Math's Version of the Nobel Prize

iStock.com/perfectlab
iStock.com/perfectlab

Every year since 2003, the Norwegian Academy of Science and Letters has bestowed the Abel Prize for excellence and contributions in the field of mathematics. Every year, the recipient has been a man. In 2019, Karen Uhlenbeck crushed that dubious tradition and became the first woman to win the Abel Prize and its $700,000 award.

An emeritus professor at the University of Texas at Austin, Uhlenbeck’s work is focused on gauge theory and geometric analysis—the latter a field she pioneered. Gauge theory supports theoretical physics and is involved in the research of particle physics and string theory. Uhlenbeck is also credited with work that led to greater comprehension of the unification of forces, a primary objective in physics that attempts to link electromagnetic force and weak nuclear force with strong nuclear force in a single theory, which would help us understand the universe.

Mathematician and Abel Prize winner Karen Uhlenbeck is seen in a portrait
Courtesy of the University of Texas at Austin

Uhlenbeck arrived at UT Austin in 1987 and stayed after her retirement in 2014. During that time, she co-founded several programs, including the Saturday Morning Math Group and Distinguished Women in Mathematics lecture series, both in Texas, as well as the Park City Mathematics Institute and the Woman and Mathematics program at the Institute for Advanced Study in Princeton, New Jersey.

She achieved another milestone in her field in 1990, when she became the second woman (and the first since 1932) to host a plenary lecture at the International Congress of Mathematicians.

The Abel Prize, which is modeled after the Nobel Prize, is named after Norwegian mathematician Niels Hendrik Abel. Uhlenbeck will receive the prize in Oslo on May 21.

[h/t New Scientist]

SECTIONS

arrow
LIVE SMARTER