10 Facts About Crohn’s Disease

iStock.com/Carlo107
iStock.com/Carlo107

Crohn’s disease is an inflammatory bowel disease in which the immune system attacks the lining of the intestine, usually the ending of the small intestine (called the ileum) or the colon. But it's more than just a case of irritable bowels. Crohn's disease symptoms range from abdominal cramps to ulcers that eat through the intestinal wall, and the complications—including pain, diarrhea, and malnutrition—can be sometimes be fatal. But with a proper diagnosis and the right medical care, managing the condition is possible for patients with Crohn’s. Here are more facts about Crohn's disease, from testing to treatments.

1. Crohn's disease causes are unknown, but genetics may be involved.

The exact causes of Crohn’s disease haven’t been identified, but for many people, family history plays a role. About 15 percent of Crohn’s patients share the diagnosis with a first-degree relative (parent, sibling, or child). Whether the family cluster patterns have more to do with genetics or environment is still unclear, though environmental factors appear to have more of an impact on the development of Crohn's disease symptoms. Scientists have also identified more than 200 gene variants that could influence Crohn's disease risk, mostly affecting genes related to immune system function.

2. Crohn's disease symptoms can come and go.

Crohn’s disease is characterized by inflammation of the digestive tract, and common signs include abdominal pain, rectal bleeding, diarrhea, fatigue, and fever. In severe cases, the inflammation can cause ulcers in the intestinal wall that prevents nutrient absorption, which can lead to weight loss and malnutrition. The intensity of these symptoms can be unpredictable. Flare-ups of gastrointestinal distress can last weeks to months, and there can also be long stretches of time when patients live symptom-free. Anti-inflammatory treatments can encourage the symptoms to go into remission, but the disease can never be cured completely.

3. Your diet can make Crohn's disease symptoms worse.

Doctors used to think of diet as one of the main causes of Crohn’s disease, but now it’s just thought to be a factor that exacerbates the symptoms. Certain foods can aggravate the digestive systems of people with Crohn’s. High-fiber foods, such fruits, vegetables, and whole grains, are some of the worst culprits, though cooked fruits and vegetables are generally gentler on the GI tract than raw ones.

4. Crohn's disease and ulcerative colitis are not the same.

People commonly confuse ulcerative colitis (UC) and Crohn’s disease. The two conditions are both inflammatory bowel diseases (which are different than irritable bowel syndrome, or IBS, which involves intestinal muscle contractions rather than inflammation). Both UC and Crohn's disease share symptoms such as weight loss, rectal bleeding, and diarrhea. But they differ in important ways: UC is limited to the large intestine, while Crohn’s disease can develop anywhere on the gastrointestinal tract between the mouth and anus. UC inflammation is also concentrated on the innermost intestinal lining, whereas can Crohn’s can penetrate the entire bowel wall. If you suspect you have an IBD, a doctor can help you identify the exact condition.

5. Crohn's disease can also affect the joints, eyes, and skin.

Crohn’s disease is known as a gastrointestinal disease, but the symptoms can extend beyond the digestive tract. People experiencing inflammation in the colon can also have inflammation in the joints. Up to 25 percent of patients with Crohn’s or UC also suffer from arthritis. Other complications include inflammation of the skin and eyes. Because eye tissue is so sensitive, ocular symptoms like redness and itchiness often appear before the first gastrointestinal signs.

6. A fecal occult blood test is one way to diagnose Crohn's disease.

There’s no one test for Crohn’s disease. Instead, doctors diagnose the condition by performing a series of tests to rule out other possible ailments. Testing poop samples with a fecal occult blood test can reveal hidden (or occult) blood in a patient’s stool, and testing antibodies can indicate whether symptoms are caused by Crohn’s or UC. Imaging tests—such as an ultrasound, MRI, X-ray, CT scan, or colonoscopy—gives doctors visual clues to the extent of a patient’s condition.

7. Incidence of Crohn's disease is increasing.

Crohn’s affects people of all ages, but symptoms usually appear in younger patients: People in the 15-to-35 age group are most likely to be diagnosed with the condition. Childhood cases of Crohn’s disease can lead to complications like delayed growth. Some studies have shown that the disease is becoming more prevalent, especially in Western countries and in children. Researchers think the "Westernized lifestyle" of poor-quality diet and lack of exercise are contributing factors to the increase.

8. Crohn's disease complications can be deadly.

If left untreated, Crohn’s disease can lead to some life-threatening complications. Inflammation can permanently damage the intestines, scarring parts the GI tract and causing tissue to thicken. In some cases, the damage is so severe that the bowel becomes blocked and surgery is required to remove the obstruction. Another possible complication is a fistula: an ulcer that has penetrated the intestinal wall and connected into a different part of the body, such as another organ or skin. An infected fistula is potentially fatal if ignored. Crohn's disease also increases a patient's risk of developing colorectal cancer. Inflammatory bowel disease is the third highest risk factor for colorectal cancer cases, though IBD-related cancer incidence is decreasing in some countries.

9. Surgery is a last resort for Crohn's disease.

Though Crohn’s disease can’t be cured, it can be managed. Most patients are initially put on anti-inflammatory medications. Other drugs, like pain relievers, nutritional supplements, and anti-diarrheal medications, are prescribed to treat the symptoms of the disease. If the condition doesn't improve, patients may require surgery to remove damaged portions of the bowel, close fistulas, and drain abscesses. Doctors may also recommend specific dietary changes to avoid flare-ups.

10. Crohn's disease was identified in the 1930s.

In 1932, gastroenterologist Burrill B. Crohn and his colleagues Leon Ginzburg and Gordon D. Oppenheimer identified the condition now known as Crohn’s disease, which Crohn called ileitis (meaning inflammation of the ileum). Prior to the report, the condition was thought to be type of a tuberculosis and not an inflammatory bowel disease. In addition to helping define the disease that bears his name, Crohn was one of the first medical professionals to link gastrointestinal distress to anxiety. He also published a book with the charming title Affections of the Stomach in 1927 and commented in media reports when President Dwight D. Eisenhower came down with ileitis symptoms in 1956.

How 25 of Your Favorite Halloween Candies Got Their Names

iStock/mediaphotos
iStock/mediaphotos

Soon, small superheroes and ghosts and all sorts of other strange creatures will be canvassing your neighborhood begging for candy. But as you pass out your wares, you can also dole out some (not terribly spooky) etymologies.

1. 3 MUSKETEERS

3 Musketeers candy bar.
Erin McCarthy

When 3 Musketeers bars were introduced in 1932, they consisted of three flavors—chocolate, vanilla, and strawberry—and were labeled "The 3 Musketeers, Chocolate, Vanilla, Strawberry. 3 bars in a package.' Eventually the vanilla and strawberry flavors would disappear, although there’s evidence that they weren't ever particularly important flavors. A 1933 Notice of Judgment from the Acting Secretary of Agriculture describes a shipment of the treats that was seized in part because "[t]he strawberry and vanilla bars had no recognizable flavor of strawberry or vanilla and the strawberry bars were also artificially colored."

2. AIRHEADS

Pile of AirHeads candy.
Jasmin Fine, Flickr // CC BY-ND 2.0

According to Steve Bruner, who invented the name, he had heard that it takes a generation for a candy name to become part of the collective consciousness—unless it was already a commonly used word. So he asked his children, "What would you call your friend who did something silly?" and one of them came up with 'Airhead.'

3. BUTTERFINGER

Three Butterfinger candy bars.
Amira Azarcon, Flickr // CC BY-NC-ND 2.0

According to legend, the Curtiss Candy Company of Chicago decided to run a contest to name their new candy bar, and someone suggested 'butterfinger,' a term used in the form "butter-fingered" since the early 17th century to describe someone who lets things fall from their hands.

4. CANDY CORN

Jack-o-lantern mug full of candy corn.
iStock

In the late 19th century, confections shaped like other things were all the rage (the Candy Professor tells of children then eating candies shaped like cockroaches … for Christmas). Candy corn was invented around this time, and was a stand-out novelty product because real corn kernels—which the candy vaguely resembled—were then mainly a food for livestock, not people.

5. DUM DUMS

Jar of Dum Dums lollipops.
Sarah Browning, Flickr // CC BY-NC 2.0

According to the Spangler Candy Company, the manufacturer, the name Dum Dum was chosen because it "was a word any child could say."

6. HEATH BAR

Two Heath candy bars.
Erika Berlin

In 1914, L.S. Heath decided to buy a candy shop and soda fountain so his children could have a good career. Several years later, the family got hold of the toffee recipe (potential sources range from a traveling salesman to nearby Greek candy makers) that made them famous, especially after they started supplying candy to troops during WWII.

7. HERSHEY'S

Hershey's chocolate bars in a basket.
slgckgc, Flickr // CC BY 2.0

Milton Hershey had worked for a few years in various candy businesses, but it was in Denver that he came across the caramel recipe that would become a massive hit. Not resting on his laurels, he learned of the new European craze for "milk chocolate" and brought it to the masses in America.

8. HERSHEY'S COOKIES 'N' CREME

Hershey's Cookies 'n' Creme candy bar.
Like_the_Grand_Canyon, Flickr // CC BY-NC 2.0

The candy bar came about in 1994, somewhere around 15-20 years after the ice cream flavor that it was capitalizing on. Where the ice cream comes from is a mystery—claimants range from South Dakota State University to a Blue Bell Creameries employee (to make matters more difficult, many versions of the story have the invention happening after a visit to some anonymous ice cream parlor that put Oreos on their ice cream, and as early as 1959 Nabisco was suggesting that crumbled Oreos in-between layers of ice cream made a great party parfait). No matter the culinary origin, the name origin is generally agreed upon—Nabisco balked at allowing ice cream companies to use their Oreo trademark.

9. HERSHEY'S KISSES

Hershey Kisses on an orange table.
Song Zhen, Flickr // CC BY-NC-ND 2.0

Over 100 years ago, kiss was a generic term for any number of small pieces of confectionery. So when Hershey came out with their product, it was a natural generic name. As years went by and "kiss" lost this particular meaning, Hershey was able to assert control over the name.

10. JOLLY RANCHERS

Bowl of Jolly Rancher candies.
Thomas Hawk, Flickr // CC BY-NC 2.0

When William and Dorothy Harmsen set out to Colorado, their goal was to start a small farm/ranch. Eventually, they decided to open up an ice cream parlor named The Jolly Rancher, evoking both Western hospitality and the Jolly Miller—a hotel in their native Minnesota. The story goes that as sales declined in the winter months, the Harmsens decided to add candies to their menu, which soon outstripped the popularity of all their other offerings.

11. KIT KAT

No one is quite sure where this comes from. The oldest use of the word "kit-cat" in the Oxford English Dictionary is from 1665 to describe a game more commonly known as tipcat, but this is probably coincidence. More likely is that it’s somehow related to the Kit-Cat Club of the early 18th century, which met at a place operated by a mutton pieman named something like Christopher Katt or Christopher Catling. Both he and his pies were named Kit-Kats/Kit-Cats (the prologue to the 1700 play The Reformed Wife even has a line "A Kit-Cat is a supper for a lord"), and the club took its name from either the pie or the pieman.

The jump from a gentleman's club or mutton pie to a candy is more mysterious. A popular theory is that it's related to kit-cat pictures, a type of portrait that the OED describes as "less than half-length, but [includes] the hands." But like most other hypotheses, this doesn't really work because the producer, Rowntree's, registered the name years before there was a candy to go with it, and the candy was originally known as Rowntree’s Chocolate Crisp. Most likely is that someone just liked the name.

12. LIFE SAVERS

Pile of Life Savers candies.
Erika Berlin

The name Life Savers is fairly self-explanatory—they're broadly shaped like a life saver. (Any rumors of the hole existing to prevent a choking death have no merit.)

13. MILKY WAY

Milky Way candy bar.
Like_the_Grand_Canyon, Flickr // CC BY-NC 2.0

Before 1970, Milky Way had a very different connotation. That year, headlines in newspapers across the country blared "FTC Decides Candy Bar Isn't Equal to Milk." The reason for this headline is that the FTC criticized Mars for implying in their advertising things like "Milky Way's nutritional value is equivalent to a glass of milk" and 'That it can and should be substituted for milk." (Odd nutrition claims were nothing new though—early on, Hershey’s advertised their chocolate bars as being "more sustaining than meat.")

While the galaxy certainly helped with the name, the original focus of the Milky Way was about how "milky" it was, and specifically that it was milkier than a malted milk you could get at a soda fountain.

14. M&M's

Bag of opened M&Ms.
iStock

The two Ms stand for Mars and Murrie. This Mars was Forrest Mars, the son of Mars candy company founder Frank Mars. Forrest and Frank had a falling out, which resulted in Forrest going to Europe and founding his own candy company (many years later, he would return to take over Mars, Inc after his father's death).

How he came up with the idea for M&M's is a bit mysterious (with versions ranging from wholesale ripoff to inspiration during the Spanish Civil War), but is generally related to a candy-covered British chocolate called Smarties (unrelated to the American Smarties). When Forrest Mars returned to the United States to make these candies, he recognized that he needed a steady supply of chocolate. At the time, Hershey was a major supplier of chocolate to other businesses and was run by a man named William Murrie. Forrest decided to go into business with William's son, Bruce (which long rumored to be a shameless ploy by Forrest to ensure a chocolate supply during World War II), and they named the candy M&M's.

15. MR. GOODBAR

Bowl of Mr. Goodbar candy bars.
Erika Berlin

According to corporate history, Hershey chemists had been working on a new peanut candy bar. As they were testing it, someone said "that's a good bar" which Milton Hershey misheard as "Mr. Goodbar."

16. REESE'S PEANUT BUTTER CUPS

Stack of Reese's Peanut Butter Cups.
Sheila Sund, Flickr // CC BY-NC 2.0

Harry Burnett Reese started working for the Hershey Chocolate Company in 1916 as a dairy farmer, but after leaving and returning to Hershey's a few times over the following years, Reese set out on his own. His great peanut butter cup invention was supposedly inspired by a store owner who told him that they were having difficulties with their supplier of chocolate-covered peanut butter sweets.

17. SKITTLES

Bags of Skittles in a vending machine.
calvinnivlac, Flickr // CC BY-NC-ND 2.0

Skittles originated in the United Kingdom, where "skittles" is a type of bowling, either on lawns or on a tabletop in pubs. The phrase "beer and skittles" emerged to describe pure happiness (now more commonly seen in "life is not beer and skittles"). So the name for the candy likely emerged to associate it with fun.

18. SNICKERS

Bunch of Snickers fun size candies.
iStock

The candy bar was named after the Mars family horse. The Mars family was very into horses, even naming their farm the Milky Way Farm—which produced the 1940 Kentucky Derby champion Gallahadion.

19. SOUR PATCH KIDS

Two bags of Sour Patch Kids.
Mike Mozart, Flickr // CC BY 2.0

Originally called Mars Men, the Sour Patch Kid was renamed to capitalize on the popularity of the '80s craze of Cabbage Patch Kids.

20. TOBLERONE

Close-up of a Toblerone candy bar.
Helena Eriksson, Flickr // CC BY-NC-ND 2.0

The Toblerone is a portmanteau of the candy inventor—Theodor Tobler—and torrone, a name for various Italian nougats. As for the distinctive triangle shape, it's generally credited to the Swiss Alps, but Toblerone’s UK site suggests something a little racier—"a red and cream-frilled line of dancers at the Folies Bergères in Paris, forming a shapely pyramid at the end of a show.”

21. TOOTSIE ROLL

Pile of Tootsie Roll candies.
Lynn Friedman, Flickr // CC BY-NC-ND 2.0

The official story is that in the late 19th century, Leo Hirschfeld invented the Tootsie Roll—Tootsie coming from his daughter's nickname. But the Candy Professor has blown multiple holes in the official story, finding evidence from patents to trademark filings that show Tootsie Rolls came into existence circa 1907. And as for the Tootsie? The Candy Professor has also found that the company that applied for those trademarks had an earlier product called Bromangelon that had as a mascot the character "Tattling Tootsie." Whether this Tootsie was named after Hirschfeld’s daughter or something mysterious is still debated.

22. TWIX

Twix candy bar.
iStock

The meaning behind Twix has been lost to time (and marketing). But the general consensus is that it's a portmanteau of twin and sticks (stix), or possibly twin and mix.

23. TWIZZLERS

Bag of Twizzlers candy.
iStock

Another term where the true origin is unknown, but it’s certainly related to the word twizzle, which dates back to the 18th century. One of the definitions the Oxford English Dictionary gives is "To twirl, twist; to turn round; to form by twisting."

24. YORK PEPPERMINT PATTIES

Two York Peppermint Patties
Barb Watson, Flickr // CC BY-NC 2.0

The popular patties were originally created by the York Cone Company out of York, Pennsylvania, which made ice cream cones before going all in on their new invention. As for the "Peanuts" character Peppermint Patty, Charles Schulz said that the name inspiration was "A dish of candy sitting in our living room." But as the York version was still regional at the time, the inspiration was probably a different peppermint patty.

25. BABY RUTH

Pile of Baby Ruth mini candy bars.
Erika Berlin

A debate for the ages. Otto Schnering named the bar after either Ruth Cleveland, daughter of President Grover Cleveland (whose New York Times obituary said, "She was known to the Nation as 'Baby Ruth' while she was a child in the White House") or Babe Ruth, the famous baseball player. While Baby Ruth was a very popular name (and not just for Presidential daughters. An actress at the time of the candy bar’s introduction was known as "Baby" Ruth Sullivan), Babe Ruth proponents point out that Cleveland’s daughter died in 1904, around 17 years before the candy was introduced. But claims of a recently discovered court document has Schnering answering under oath the question "When you adopted the trade mark Baby Ruth…did you at that time [take] into consideration any value that the nickname Babe Ruth…might have?”

Schnering responded, "The bar was named for Baby Ruth, the first baby of the White House, Cleveland, dating back to the Cleveland administration…There was a suggestion, at the time, that Babe Ruth, however not a big figure at the time as he later developed to be, might have possibilities of developing in such a way as to help our merchandising of our bar Baby Ruth."

12 Quirky Books for Imaginative Kids

Simon & Schuster
Simon & Schuster

Though childhood classics like A.A. Milne's Winnie the Pooh and Maurice Sendak's Where the Wild Things Are never truly go out of style, each year brings a new cache of funny and fantastical books that will feed the expanding imaginations of young readers everywhere. From a self-conscious sewer monster who wants to make friends to a gluttonous dinosaur who gobbled up Christmas, this guide has the perfect quirky story for every kind of kid on your holiday gift list.

1. Rumple Buttercup // Matthew Gray Gubler ($9)

This whimsical tale about a self-conscious sewer monster is written and illustrated by Criminal Minds star, and king of quirk, Matthew Gray Gubler. While cute characters and a simple message about embracing your individuality make it a great gift for very young kids, its absurdist humor makes it a laugh-out-loud read for older kids and adults, too.

Buy it: Amazon

2. President Taft Is Stuck in the Bath // Mac Barnett ($8)

president taft is stuck in the bath
Candlewick/Amazon

Mac Barnett’s good-natured retelling of William Howard Taft’s infamous (though unconfirmed) bathtub blunder teaches children two things. One, history is far from a tedious list of names, dates, laws, and battles. And two, even the most stately world leaders have embarrassing moments.

Buy it: Amazon

3. It’s Only Stanley // Jon Agee ($15)

it's only stanley book
Dial Books/Amazon

When strange noises wake the Wimbledon family at night, they assume their dog Stanley is cleaning or fixing something; in reality, Stanley is transforming their house into a rocket ship that will carry them to an alien-inhabited planet. Fans of The Secret Life of Pets and Phineas and Ferb’s Perry the Platypus will love this rhyming read-aloud (and surely wonder what their own pet is up to when they’re not around).

Buy it: Amazon

4. Frankie Sparks and the Big Sled Challenge // Megan Frazer Blakemore ($6)

frankie sparks and the big sled challenge
Aladdin/Amazon

Third-grade inventor Frankie Sparks is back for the third book in her STEM-inspired series, and this time, she’s about to learn that the hardest part about creating a competition-winning sled is less about sled-building and more about team-building. Great for elementary school kids who love to create anything—be it art or architecture—as well as anyone who’s ever had to work on a group project.

Buy it: Amazon

5. The Pigeon HAS to Go to School! // Mo Willems ($10)

the pigeon has to go to school
Hyperion Books/Amazon

Mo Willems’s original pigeon book was Don’t Let the Pigeon Drive the Bus!, a thoroughly riotous, award-winning tale about a pigeon trying to convince readers to let it drive the bus when the bus driver asked them not to. In the latest story, the headstrong pigeon pivots to something it very much does not want to do—go to school. It sends a message about the value of doing things you don’t want to do, but, most importantly, it’s also really funny.

Buy it: Amazon

6. The Glass Town Game // Catherynne M. Valente ($11)

the glass town game
Simon & Schuster/Amazon

Catherynne M. Valente spins a riveting fictional tale from the true story of Charlotte, Emily, Anne, and Branwell Brontë’s childhood in a Yorkshire parsonage, where they passed the time dreaming up an intricate fantasy land populated with toy soldiers. In Valente’s novel, the fantasy land comes to life, complete with whale-sized flies, Champagne flutes that play music, and fire-breathing porcelain roosters, and the siblings must use all their wit and imagination to figure out how to get home. It’s a little like Alice in Wonderland meets The Chronicles of Narnia, and perfect for fans of both.

Buy it: Amazon

7. Lambslide // Ann Patchett ($13)

lambslide
HarperCollins/Amazon

The internationally bestselling author of Bel Canto and Commonwealth is just as clever when it comes to writing for kids. In Lambslide, a group of lambs mistakenly hear lambslide instead of landslide and begin a farm-wide campaign for an actual slide for lambs. With quaint illustrations, endearing characters, and an engaging plot, this is the type of book that ends up in the family for generations.

Buy it: Amazon

8. The Book With No Pictures // B.J. Novak ($9)

The Office alum B.J. Novak turns storytime into a full-fledged comedic performance with The Book With No Pictures, a book filled with nonsense words and phrases like blork and blaggity blaggity, which the reader has to read aloud. For parents, it’s a blueprint for embracing their silly side. For kids, it’s a chance to see their parents not seem so parental.

Buy it: Amazon

9. Spencer’s New Pet // Jessie Sima ($14)

spencer's new pet
Simon & Schuster/Amazon

The author of Not Quite Narwhal returns with another adorable story, this time about a boy who must avoid sharp objects in order to protect his balloon-animal pet dog. The mostly black-and-white illustrations (except for the dog, which is red) give Spencer’s New Pet a refreshingly old-fashioned feel, and the tale itself is sweet, evenly paced, and timeless.

Buy it: Amazon

10. Serafina and the Black Cloak // Robert Beatty ($8)

serafina and the black cloak
Disney-Hyperion/Amazon

When children begin disappearing from the Biltmore Estate, Serafina, who secretly lives in the basement, knows the culprit is a mysterious man in a black cloak who prowls the corridors at night. This novel has everything a quality middle-grade fantasy needs, including secret passageways, a forbidden forest, unknown magic, and a scrappy heroine. And the chills and thrills don’t stop at the end—it’s the first in a series of four (so far).

Buy it: Amazon

11. The Dinosaur That Pooped Christmas // Tom Fletcher and Dougie Poynter ($18)

the dinosaur that pooped christmas
Aladdin/Amazon

This jolly, strange story about a ravenous pet dinosaur who gobbles up all of Christmas is hilarious enough on its own—and perhaps even more so when you consider that it was written by British punk rockers Tom Fletcher and Dougie Poynter from the band McFly.

Buy it: Amazon

12. This Is a Taco! // Andrew Cangelose ($16)

this is a taco
Lion Forge/Amazon

A high-spirited, unique squirrel named Taco provides color commentary on regular squirrel facts in This Is a Taco!, a book that is much more than a factual guide to squirrels. In it, Taco embellishes, acts out, and sometimes completely changes the facts to be truer to his personal experience as a squirrel, which involves being opinionated and eating lots of tacos.

Buy it: Amazon

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