12 Facts About Kidney Stones

Illustration by Mental Floss. Images: iStock
Illustration by Mental Floss. Images: iStock

Kidney stones are more common than ever. According to Harvard Medical School, every year more than 3 million people see a doctor for relief from these hard mineral and salt deposits, which form in your kidney when urine becomes too concentrated. Here's what we know about the condition formally called nephrolithiasis.

1. KIDNEY STONES TYPICALLY CAUSE REALLY PAINFUL SYMPTOMS.

At first you may notice your urine is cloudy, bloody, and foul smelling. Your back may begin to ache, and nausea may come over you. Then, as the stone moves from your kidney into your urinary tract or bladder, sometimes becoming trapped, there’s often an intense, stabbing pain that many people say they wouldn’t wish on their worst enemy.

2. MOST PEOPLE DEVELOP ONE TYPE OF STONE …

What kind of kidney stone you get depends on your diet, fluid intake, genetics, hereditary disorders, and even whether you take certain medications, but the vast majority of people get calcium oxalate stones. They're formed from a mix of calcium in urine and the compound oxalate, which is found naturally in food like nuts, chocolate, and some vegetables, including beets and spinach; oxalate is also produced by your liver. There's some evidence that people who take the seizure medicine topiramate can develop these stones in the form of calcium phosphate.

3. … BUT THERE ARE THREE OTHER KINDS TOO.

Struvite stones are fast-growing mineral deposits that typically develop in response to a urinary tract infection, and can grow large enough to block the kidney, ureter, or bladder before you notice any symptoms; they affect women more than men. Uric acid stones turn up in people who eat a lot of red meat, shellfish, and organ meats, which contain hefty doses of an organic compound called purine that can lead to more uric acid than the kidneys can excrete. Cystine stones are caused by a rare hereditary disorder called cistinuria in which your kidneys excrete excessive amounts of the amino acid cystine.

4. THEY'RE EXTREMELY COMMON—ESPECIALLY IN MEN.

There's a solid chance you could end up with a kidney stone. The National Kidney Foundation notes that one in 10 people will develop one during the course of their life. And if you’re male, take note: Your gender alone is considered a kidney stone risk factor. Men are twice as likely as women to develop them. Another factor is age: Although stones are most common from ages 20 through 50, they tend to peak around age 30.

5. IF YOU’VE HAD A KIDNEY STONE, YOU’LL PROBABLY DEVELOP ANOTHER ONE …

Sorry to say, but simply having a kidney stone puts you at risk for a recurrence. If you’ve had one, the U.S. National Library of Medicine notes that there’s a 30 to 50 percent chance more stones will form within five years.

6. … BUT YOU CAN TAKE STEPS TO PREVENT THEM.

Cutting back on sodium (i.e. deli meats, packaged soups, and processed foods) can help, because a stone can form from excessive salt consumption. You should also avoid too much animal protein—it produces urine containing more acid, which is known to increase your risk for kidney stones—and increase your intake of fruits, vegetables, whole grains, and low-fat dairy. And be sure to drink plenty of fluids, especially water—at least 12 glasses a day. (That's good advice for everyone, not just those prone to kidney stones.)

Don't drink much apple or cranberry juice as both contain oxalates and are linked to an increased risk of developing calcium oxalate stones. High doses of Vitamin C may boost the concentration of oxalate in urine; the Cleveland Clinic recommends a daily maximum of 500 milligrams.

7. IT'S A MYTH THAT CALCIUM CREATES SOME KIDNEY STONES.

Despite the fact that the word calcium is part of the most common kind of kidney stone, you don’t need to treat calcium as the enemy. In fact, having too little calcium can actually increase the odds you’ll get these types of stones. According to the Cleveland Clinic, eating about two or three servings of calcium-rich foods daily reduces oxalate absorption, helping to keep calcium oxalate stones away. So get out the cheese.

8. IF YOU PASS A STONE, CONGRATULATIONS! NOW TAKE IT TO A DOCTOR.

Ninety percent of kidney stones are passed through urination. Getting one out this way may hurt a lot, but once the stone has finished causing you agony, it could provide clues that could help you avoid developing another one. If you’re able to retrieve the stone, bring it to your doctor, who can order an analysis. Identifying its components can reveal the kind of stone it is and potentially point to a treatment or prevention plan.

9. IF YOU CAN’T PASS A STONE, TREATMENTS ARE AVAILABLE …

In an attempt to exit the body, a stone travels from the kidney to the bladder through a narrow tube called the ureter. If the stone is larger than a quarter-inch, it's simply too big to pass through the ureter, and will get trapped there. (If it can make it through to your bladder, it's small enough to pass out out of your body through the urethra.) This causes intense pain, blocked urine flow, and possible bleeding from urinary tract walls. That's when it's time for treatment.

There are several methods for getting rid of a kidney stone, all of which aim to break the stone into smaller pieces so they can leave the body. In an extracorporeal shock wave lithotripsy (from the Greek for "crushed stone"), high-frequency sound waves are applied externally to break stones up, allowing them to pass when you pee. Laser lithotripsy takes a similar approach: Stones in the ureter are broken up with a laser and also leave the body naturally. More invasive is percutaneous ultrasonic lithotripsy, which involves passing narrow instruments (including a fiberoptic camera) through your back to your kidney; ultrasound breaks the stones up, and then fragments are removed by an instrument. Finally, a ureteroscopy is a treatment option in which a small scope is inserted in the ureter towards the bladder to determine the stone's location. Then it's broken up for natural passage or removed altogether. Luckily, you're unconscious under general anesthesia during the last procedure.

10. … AND THEY'RE FAR SUPERIOR TO THOSE USED IN THE PAST.

Kidney stones are nothing new—mentions of the painful formations go back more than 5000 years, to Mesopotamian medical texts—and medical interventions have occurred for just as long. Stones made it into the Hippocratic Oath, in which physicians swore they would "not use the knife, not even on sufferers from stone," leaving the procedure to "such men as are engaged in this work" [PDF]. Surgeons in ancient Greece and India were attempting stone removal as far back as the 7th century BCE.

The 16th to 18th centuries were a heyday for stone surgeons, who were largely self-taught. The most notorious of them was Frere Jacques Beaulieu. He pioneered the lateral perineal lithotomy—which involved making an incision in the perineum, inserting a terrifying cutting instrument into the bladder, cutting up the stone, and then extracting the pieces with the instrument or his fingers—in the late 17th century. Unfortunately for his patients, he had no technical training, and his method was often deadly; in 1698, after 25 of his 60 patients died, he was banned from doing the procedure—but he didn't stop. He's thought to have performed more than 5000 lithotomies. (And no, the song doesn't seem to be about him.)

11. IF ALL ELSE FAILS, TRY RIDING A ROLLER COASTER.

If you’re a thrill seeker who happens to have kidney stones (and some vacation time), you may be in luck. After a "notable number" of patients reported that riding the Big Thunder Mountain roller coaster at Walt Disney World in Orlando helped them to pass their kidney stones, Michigan State University urologist David Wartinger decided to investigate. He created a kidney replica—complete with kidney stones—put it in a backpack, and let it ride the roller coaster 60 times. It worked—but passing the stones depended on where the backpack was placed in the coaster. Rides in the last car were the most effective, with the stones passing 64 percent of the time, while the front few cars yielded only a 16 percent success rate.

Big Thunder Mountain was the only ride in the theme park that was effective. Neither Space Mountain nor Aerosmith's Rock 'n' Roller Coaster did the trick, likely because they were too fast, with a G-force that pinned the stones in place. Of course, while this is an interesting finding, if you suspect you have kidney stones, speak to your doctor before you high-tail it to Walt Disney World.

12. A KIDNEY STONE THE SIZE OF A MOUSE WAS REMOVED FROM A MAN IN 2004.

The stone measured 5.11 inches at its widest point—a world record. Five years later, a whopping 2.5-pound stone was surgically removed from a man in Hungary in 2009. Perhaps seeing a bunch of kidney stones in one place other than originating from your own body will put you at ease. If that’s the case, check out the International Museum of Surgical Science in Chicago, where a collection of stones is on display in glass jars.

Game of Thrones Star Sophie Turner Opened Up About Her Struggles With Depression

Helen Sloan, HBO
Helen Sloan, HBO

Playing one of the main characters on the most popular show currently on television isn't always as glamorous as it seems. Sometimes, the pressures of fame can be too much. Sophie Turner realized this while playing Sansa Stark on Game of Thrones, and has recently revealed how being in the public eye took a toll on her mental health.

Turner took on the role of Sansa Stark in 2011, when she was just a teenager, and she quickly became a household name. Now, at 23, she's come forward to Dr. Phil on his podcast Phil in the Blanks to explain how negative comments on social media affected her self-image and mental health.

"I would just believe it. I would say, ‘Yeah, I am spotty. I am fat. I am a bad actress.' I would just believe it," Turned explained. "I would get [the costume department] to tighten my corset a lot. I just got very, very self-conscious."

Later on, these feelings led to major depression. Turner developed a sense of isolation after she realized that all of her friends and family were going off to colleege while she was pursuing a sometimes-lonely acting career.

"I had no motivation to do anything or go out. Even with my best friends, I wouldn't want to see them, I wouldn't want to go out and eat with them," Turner explained. "I just would cry and cry and cry over just getting changed and putting on clothes and be like, 'I can't do this. I can't go outside. I have nothing that I want to do.'"

The feelings of depression stayed with Turner for most of the time she was filming Game of Thrones, and it's a battle she's still fighting. "I've suffered with my depression for five or six years now. The biggest challenge for me is getting out of bed and getting out of the house. Learning to love yourself is the biggest challenge," she continued.

The actress shared that she goes to a therapist and takes medication for her depression—two things that have helped her feel better.

Between Game of Thrones ending and planning her wedding to fiancé Joe Jonas, Turner may not have the time to take on many new acting roles in the near future. However, we'll continue to see her as Sansa Stark in the final season of Game of Thrones, and as Jean Grey in Dark Phoenix, which hits theaters on June 7.

[h/t: E! News]

10 Facts About High Blood Pressure

iStock.com/stockvisual
iStock.com/stockvisual

People with high blood pressure (hypertension) are at a greater risk for a host of medical issues, including heart failure and stroke. Despite the severe health threats it poses, high blood pressure often goes unnoticed or untreated by some who have it. From high blood pressure symptoms to what levels are considered normal, here are some facts about the condition.

1. High blood pressure symptoms are sometimes unnoticeable.

Blood pressure is a measurement of the force of blood moving through the circulatory system. High blood pressure, a condition in which blood is putting too much force on arteries and organs, is often called the “silent killer.” It contributes to hundreds of thousands of deaths each year, but only half of high blood pressure patients know they have it. In most cases, hypertension signs are difficult to detect, making it hard to diagnose and keep under control. Chest pain, dizziness, shortness of breath, and heart palpitations are some of the most common hypertension signs in people who do show symptoms.

2. Anxiety causes some of the same symptoms as high blood pressure.

When it comes to managing high blood pressure symptoms, mental health is as important as physical health. Anxiety can lead to sudden spikes in blood pressure, and spikes that occur often enough can inflict serious damage on the heart and blood vessels the same way chronic high blood pressures does. Stress and anxiety also make people vulnerable to the top risk factors associated with chronic hypertension, such as smoking, excessive drinking, and overeating.

3. A normal blood pressure range is lower than it used to be.

If you haven’t had your blood pressure measured in a couple years, it’s time for a check-up: In November 2017, the American College of Cardiology and the American Heart Association updated its normal blood pressure guidelines. The two components that make up blood pressure are systolic pressure—the pressure in blood vessels, represented by the top number in test results—and diastolic pressure, the pressure in the heart between beats represented by the bottom number. According to the old guidelines, the threshold for normal blood pressure was 140 systolic pressure and 90 diastolic pressure, or 140/90. The new guidelines lowered that marker to 130/80. Now that the normal blood pressure range has dropped, 14 percent more people could diagnosed with hypertension in the U.S.

4. "White-coat hypertension" is real.

Not every patient who exhibits hypertension signs in the doctor’s office has high blood pressure. “White-coat hypertension” occurs when patients get nervous in a medical setting, leading to a spike in blood pressure that doesn’t necessarily reflect their true health. But this type of hypertension should be taken seriously, even if it is a product of nerves. According to one study, people with white-coat hypertension have a greater chance of developing cardiovascular disease than those with normal blood pressure levels. This may be because people with white-coat hypertension are more prone to anxiety.

5. People with high blood pressure should consume less than one teaspoon of salt per day.

One of the worst things to eat if you have hypertension is food that’s high in salt. Sodium, which makes up 40 percent of table salt (sodium chloride), promotes water retention in the body. More water means more blood volume, which puts added pressure on the heart and blood vessels. Medical experts recommend consuming no more than 2300 milligrams of sodium per day, or just over 1 teaspoon of salt. If you have high blood pressure, the American Heart Association recommends an ideal limit at 1500 milligrams of sodium a day—equal to three-quarters of a teaspoon of salt.

6. Almost half of U.S. adults have high blood pressure ...

According to the American Heart Association, more than 100 million people in the U.S. have high blood pressure—that’s nearly half of American adults. The condition is so common that even if you don’t have it now, chances are you will develop it at some point in your life. The lifetime risk in the U.S. for hypertension in 90 percent.

7. ... and black Americans are most affected.

High blood pressure affects certain groups disproportionately. Black Americans are more likely to have high blood pressure than any other group in the country, and when they develop it, it’s usually more severe. Hypertension also affects black Americans earlier in life: Three in four black people in the U.S. will develop the condition by age 55. Health experts believe that the prevalence of high blood pressure is associated with the higher rates of obesity and diabetes among the black population.

8. A female hormone may protect against high blood pressure.

High blood pressure rates are pretty similar among men and women before middle age. But once women hit menopause, their chances of developing hypertension increase: 75 percent of postmenopausal in the U.S. have high blood pressure. This may have to do something with decreased levels of estrogen—a hormone that’s been shown to boost premenopausal women’s vascular health.

9. High blood pressure can be life-threatening ...

High blood pressure doesn’t kill people directly, but it can lead to some deadly complications. Hypertension adds potentially fatal stress to vital organs like the heart, kidneys, and brain. When you have high blood pressure, your risk of heart attack, stroke, chronic heart failure, kidney disease, and even blindness all significantly go up.

10. ... but improved with medications and healthy living.

The best way to reduce your blood pressure is to change your lifestyle. Smoking, drinking too much alcohol, and eating too much salty food all increase your risk of developing hypertension, and doctors recommend avoiding these risk factors to keep blood pressure levels under control. Regular exercise and certain medications, like diuretics (to get rid of excess water in the body) and ACE inhibitors (which block an enzyme that tightens blood vessels), can also lower blood pressure.

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