More Evidence to Suggest That Your Insomnia Is Genetic

iStock
iStock

In 2016, a study on mice found that certain sleep traits, like insomnia, have genetic underpinnings. Several studies of human twins have also suggested that insomnia can be an inherited trait. Now, new research published in Molecular Psychiatry not only reinforces that finding, but also suggests that there may be a genetic link between insomnia and some other psychiatric and physical disorders, like depression and type 2 diabetes, as Psych Central alerts us.

Insomnia is particularly prevalent in populations of military veterans. For this study, researchers at VA San Diego Healthcare System analyzed questionnaire responses and blood samples from almost 33,000 new soldiers at the beginning of basic training, along with pre- and post-deployment surveys from nearly 8000 soldiers deployed to Afghanistan starting in early 2012. They conducted genome-wide association tests to determine the heritability of insomnia and links between insomnia and other disorders. The results were adjusted for the presence of major depression (since insomnia is a common symptom of depression).

The genotype data showed that insomnia disorder was highly heritable and pinpointed potential genes that may be involved. The study indicated that there's a strong genetic correlation between insomnia and major depression. (The two were distinct, though, meaning that the insomnia couldn't be totally explained by the depression.) They also found a significant genetic correlation between insomnia and type 2 diabetes.

Because the study relied on data from the U.S. military, the study doesn't have the most far-reaching sample—it was largely male and wasn't as racially diverse as it could have been. (While it analyzed responses from recruits from European, African, and Latino ancestry, there weren't enough Asian-American participants to analyze as a group.) The responses were also self-reported, which isn't always the most accurate data-collection method.

The genes indicated by this study could be used to develop new treatments for insomnia, but future studies will likely need to explore these questions within broader populations.

[h/t Psych Central]

No Venom, No Problem: This Spider Uses a Slingshot to Catch Prey

Courtesy of Sarah Han
Courtesy of Sarah Han

There are thousands of ways nature can kill, and spider species often come up with the most creative methods of execution. Hyptiotes cavatus, otherwise known as the triangle weaver spider, is one such example. Lacking venom, the spider manages to weaponize its silk, using it to hurl itself forward like a terrifying slingshot to trap its prey.

This unusual method was studied up close for a recent paper published in the Proceedings of the National Academy of Sciences by researchers at the University of Akron in Ohio. They say it's the only known instance of an animal using an external device—its web—for power amplification.

Hyptiotes cavatus's technique is simple. After constructing a web, the spider takes one of the main strands and breaks it in half, pulling it taut by moving backwards. Then, it anchors itself to a spot with more webbing in the rear. When the spider releases that webbing, it surges forward, propelled by the sudden release of stored energy. In the slingshot analogy, the webbing is the strap and the spider is the projectile.

This jerking motion causes the web to oscillate, tangling the spider's prey further in silk. The spider can repeat this until the web has completely immobilized its prey, a low-risk entrapment that doesn’t require the spider to get too close and risk injury from larger victims.

The triangle weaver spider doesn’t have venom, and it needs to be proactive in attacking and stifling prey. Once a potential meal lands in its web, it’s able to clear distances much more quickly using this slingshot technique than if it crawled over. In the lab, scientists clocked the spider’s acceleration at 2535 feet per second squared.

Spiders are notoriously nimble and devious. Cebrennus rechenbergi, or the flic-flac spider, can do cartwheels to spin out of danger; Myrmarachne resemble ants and even wiggle their front legs like ant antennae. It helps them avoid predators, but if they see a meal, they’ll drop the act and pounce. With H. cavatus, it now appears they’re learning to use tools, too.

[h/t Live Science]

Bad News: The Best Time of the Day to Drink Coffee Isn’t as Soon as You Wake Up

iStock.com/ThomasVogel
iStock.com/ThomasVogel

If you depend on coffee to help get you through the day, you can rest assured that you’re not the world's only caffeine fiend. Far from it. According to a 2018 survey, 64 percent of Americans said they had consumed coffee the previous day—the highest percentage seen since 2012.

While we’re collectively grinding more beans, brewing more pots, and patronizing our local coffee shops with increased frequency, we might not be maximizing the health and energy-boosting benefits of our daily cup of joe. According to Inc., an analysis of 127 scientific studies highlighted the many benefits of drinking coffee, from a longer average life span to a reduced risk for cancer, heart disease, type 2 diabetes, and Parkinson’s disease.

Sounds great, right? The only problem is that the benefits of coffee might be diminished depending on the time of day that you drink it. Essentially, science tells us that it’s best to drink coffee when your body’s cortisol levels are low. That’s because both caffeine and cortisol cause a stress response in your body, and too much stress is bad for your health for obvious reasons. In addition, it might end up making you more tired in the long run.

Cortisol, a stress hormone, is released in accordance with your circadian rhythms. This varies from person to person, but in general, someone who wakes up at 6:30 a.m. would see their cortisol levels peak in different windows, including 8 to 9 a.m., noon to 1 p.m., and 5:30 to 6:30 p.m. Someone who rises at 10 a.m. would experience cortisol spikes roughly three hours later, and ultra-early risers can expect to push this schedule three hours forward.

However, these cortisol levels start to rise as soon as you start moving in the morning, so it isn’t an ideal time to drink coffee. Neither is the afternoon, because doing so could make it more difficult to fall asleep at night. This means that people who wake up at 6:30 a.m. should drink coffee after that first cortisol window closes—roughly between 9:30 a.m. and 11:30 a.m.—if they want to benefit for a little caffeine jolt.

To put it simply: "I would say that mid-morning or early afternoon is probably the best time," certified dietitian-nutritionist Lisa Lisiewski told CNBC. "That's when your cortisol levels are at their lowest and you actually benefit from the stimulant itself."

[h/t Inc.]

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