Scientists Identify Cells in the Brain That Control Anxiety

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iStock

People plagued with the uncomfortable thoughts and sensations characteristic of anxiety disorders may have a small group of cells in the brain to blame, according to a new study. As NPR reports, a team of researchers has identified a class of brain cells that regulates anxiety levels in mice.

The paper, published in the journal Neuron, is based on experiments conducted on a group of lab mice. As is the case with human brains, the hippocampus in mouse brains is associated with fear and anxiety. But until now, researchers didn't know which neurons in the hippocampus were responsible for feelings of worry and impending danger.

To pinpoint the cells at work, scientists from Columbia University, the University of California, San Francisco, and other institutions placed mice in a maze with routes leading to open areas. Mice tend to feel anxious in spacious environments, so researchers monitored activity in the hippocampus when they entered these parts of the maze. What the researchers saw was a specialized group of cells lighting up when the mice entered spaces meant to provoke anxiety.

To test if anxiety was really the driving factor behind the response, they next used a technique called optogenetics to control these cells. When they lowered the cells' activity, the mice seemed to relax and wanted to explore the maze. But as they powered the cells back up, the mice grew scared and didn't venture too far from where they were.

Anxiety is an evolutionary mechanism everyone experiences from time to time, but for a growing portion of the population, anxiety levels are debilitating. Generalized anxiety disorder, social anxiety disorder, and panic disorder can stem from a combination of factors, but most experts agree that overactive brain chemistry plays a part. Previous studies have connected anxiety disorders to several parts of the brain, including the hippocampus, which governs memory as well as fear and worry.

By uncovering not just how the brain produces symptoms of anxiety but the individual cells behind them, scientists hope to get closer to a better treatment. There's more work to be done before that becomes a possibility. The anxiety cells in mice aren't necessarily a perfect indicator of which cells regulate anxiety in humans, and if a new treatment does eventually come from the discovery, it will be one of many options rather than a cure-all for every patient with the disorder.

[h/t NPR]

England Is Being Invaded By a Swarm of Flying Ants That Can Be Seen From Space

Digoarpi/iStock via Getty Images
Digoarpi/iStock via Getty Images

Last week, the UK's weather service registered what seemed like a system of rain showers moving along the nation’s southern coast. But it wasn’t rain—it was a swarm of flying ants.

Though it sounds like something out of a horror film or the Old Testament, it’s actually a completely normal phenomenon that occurs in the UK every summer when a bout of hot, humid weather follows a period of rainfall, The Guardian reports. Flying ants decide it’s a good time to mate, and the queen takes to the sky, emitting pheromones that attract males.

From there, it’s survival of the fittest. The queen will out-fly most of her suitors, leaving only the strongest males to catch up and mate with her, which ensures the strength of her offspring. The others either lose their wings and fall to the ground, or become bird food. (The ants produce formic acid in their bodies as a defense mechanism, which may make gulls that eat them seem loopy.)

According to Smithsonian.com, the queen will chew off her wings after mating and fall to the ground to start a new colony, and the sperm she collected from that one flight will fertilize her eggs for the rest of her life (which could be up to 15 years in the wild).

The official, rather-romantic term for the annual aerial antics is “nuptial flight,” but locals often refer to it simply as “flying ant day.” It sometimes lasts for weeks, during which billions of the harmless insects can be seen in the skies.

A representative from the Met Office explained that its weather satellites mistook the ants for rain clouds because the radar detects the ants in the same way it sees raindrops. Dr. Adam Hart, an entomologist at the University of Gloucestershire, told The Guardian that he thinks the reason the radar registered the ants this year was a result of better satellite technology rather than an increase in the flying ant population.

[h/t Smithsonian.com]

Why Does Humidity Make Us Feel Hotter?

Tomwang112/iStock via Getty Images
Tomwang112/iStock via Getty Images

With temperatures spiking around the country, we thought it might be a good time to answer some questions about the heat index—and why humidity makes us feel hotter.

Why does humidity make us feel hotter?

To answer that question, we need to talk about getting sweaty.

As you probably remember from your high school biology class, one of the ways our bodies cool themselves is by sweating. The sweat then evaporates from our skin, and it carries heat away from the body as it leaves.

Humidity throws a wrench in that system of evaporative cooling, though. As relative humidity increases, the evaporation of sweat from our skin slows down. Instead, the sweat just drips off of us, which leaves us with all of the stinkiness and none of the cooling effect. Thus, when the humidity spikes, our bodies effectively lose a key tool that could normally be used to cool us down.

What's relative about relative humidity?

We all know that humidity refers to the amount of water contained in the air. However, as the air’s temperature changes, so does the amount of water the air can hold. (Air can hold more water vapor as the temperature heats up.) Relative humidity compares the actual humidity to the maximum amount of water vapor the air can hold at any given temperature.

Whose idea was the heat index?

While the notion of humidity making days feel warmer is painfully apparent to anyone who has ever been outside on a soupy day, our current system owes a big debt to Robert G. Steadman, an academic textile researcher. In a 1979 research paper called, “An Assessment of Sultriness, Parts I and II,” Steadman laid out the basic factors that would affect how hot a person felt under a given set of conditions, and meteorologists soon used his work to derive a simplified formula for calculating heat index.

The formula is long and cumbersome, but luckily it can be transformed into easy-to-read charts. Today your local meteorologist just needs to know the air temperature and the relative humidity, and the chart will tell him or her the rest.

Is the heat index calculation the same for everyone?

Not quite, but it’s close. Steadman’s original research was founded on the idea of a “typical” person who was outdoors under a very precise set of conditions. Specifically, Steadman’s everyman was 5’7” tall, weighed 147 pounds, wore long pants and a short-sleeved shirt, and was walking at just over three miles per hour into a slight breeze in the shade. Any deviations from these conditions will affect how the heat/humidity combo feels to a certain person.

What difference does being in the shade make?

Quite a big one. All of the National Weather Service’s charts for calculating the heat index make the reasonable assumption that folks will look for shade when it’s oppressively hot and muggy out. Direct sunlight can add up to 15 degrees to the calculated heat index.

How does wind affect how dangerous the heat is?

Normally, when we think of wind on a hot day, we think of a nice, cooling breeze. That’s the normal state of affairs, but when the weather is really, really hot—think high-90s hot—a dry wind actually heats us up. When it’s that hot out, wind actually draws sweat away from our bodies before it can evaporate to help cool us down. Thanks to this effect, what might have been a cool breeze acts more like a convection oven.

When should I start worrying about high heat index readings?

The National Weather Service has a handy four-tiered system to tell you how dire the heat situation is. At the most severe level, when the heat index is over 130, that's classified as "Extreme Danger" and the risk of heat stroke is highly likely with continued exposure. Things get less scary as you move down the ladder, but even on "Danger" days, when the heat index ranges from 105 to 130, you probably don’t want to be outside. According to the service, that’s when prolonged exposure and/or physical activity make sunstroke, heat cramps, and heat exhaustion likely, while heat stroke is possible.

Have you got a Big Question you'd like us to answer? If so, let us know by emailing us at bigquestions@mentalfloss.com.

This article has been updated for 2019.

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