12 Intriguing Facts About the Intestines

When we talk about the belly, gut, or bowels, what we're really talking about are the intestines—long, hollow, coiled tubes that comprise a major part of the digestive tract, running from the stomach to the anus. The intestines begin with the small intestine, divided into three parts whimsically named the duodenum, jejunum, and ileum, which absorb most of the nutrients from what we eat and drink. Food then moves into the large intestine, or colon, which absorbs water from the digested food and expels it into the rectum. That's when sensitive nerves in your rectum create the sensation of needing to poop.

These organs can be the source of intestinal pain, such as in irritable bowel syndrome, but they can also support microbes that are beneficial to your overall health. Here are some more facts about your intestines.

1. The intestines were named by medieval anatomists.

Medieval anatomists had a pretty good understanding of the physiology of the gut, and are the ones who gave the intestinal sections their names, which are still used today in modern anatomy. When they weren't moralizing about the organs, they got metaphorical about them. In 1535, the Spanish doctor Andrés Laguna noted that because the intestines "carry the chyle and all the excrement through the entire region of the stomach as if through the Ocean Sea," they could be likened to "those tall ships which as soon as they have crossed the ocean come to Rouen with their cargoes on their way to Paris but transfer their cargoes at Rouen into small boats for the last stage of the journey up the Seine."

2. Leonardo da Vinci believed the intestines helped you breathe.

Leonardo mistakenly believed the digestive system aided respiratory function. In 1490, he wrote in his unpublished notebooks, "The compressed intestines with the condensed air which is generated in them, thrust the diaphragm upwards; the diaphragm compresses the lungs and expresses the air." While that isn't anatomically accurate, it is true that the opening of the lungs is helped by the relaxation of stomach muscles, which does draw down the diaphragm.

3. Your intestines could cover two tennis courts ...

Your intestines take up a whole lot of square footage inside you. "The surface area of the intestines, if laid out flat, would cover two tennis courts," Colby Zaph, a professor of immunology in the department of biochemistry and molecular biology at Melbourne's Monash University, tells Mental Floss. The small intestine alone is about 20 feet long, and the large intestine about 5 feet long.

4. ... and they're pretty athletic.

The process of moving food through your intestines requires a wave-like pattern of muscular action, known as peristalsis, which you can see in action during surgery in this YouTube video.

5. Your intestines can fold like a telescope—but that's not something you want to happen.

Intussusception is the name of a condition where a part of your intestine folds in on itself, usually between the lower part of the small intestine and the beginning of the large intestine. It often presents as severe intestinal pain and requires immediate medical attention. It's very rare, and in children may be related to a viral infection. In adults, it's more commonly a symptom of an abnormal growth or polyp.

6. Intestines are very discriminating.

"The intestines have to discriminate between good things—food, water, vitamins, good bacteria—and bad things, such as infectious organisms like viruses, parasites and bad bacteria," Zaph says. Researchers don't entirely know how the intestines do this. Zaph says that while your intestines are designed to keep dangerous bacteria contained, infectious microbes can sometimes penetrate your immune system through your intestines.

7. The small intestine is covered in "fingers" ...

The lining of the small intestine is blanketed in tiny finger-like protrusions known as villi. These villi are then covered in even tinier protrusions called microvilli, which help capture food particles to absorb nutrients, and move food on to the large intestine.

8. ... And you can't live without it.

Your small intestine "is the sole point of food and water absorption," Zaph says. Without it, "you'd have to be fed through the blood."

9. The intestines house your microbiome. 

The microbiome is made up of all kinds of microorganisms, including bacteria, viruses, fungi, and protozoans, "and probably used to include worm parasites too," says Zaph. So in a way, he adds, "we are constantly infected with something, but it [can be] helpful, not harmful."

10. Intestines are sensitive to change.

Zaph says that many factors change the composition of the microbiome, including antibiotics, foods we eat, stress, and infections. But in general, most people's microbiomes return to a stable state after these events. "The microbiome composition is different between people and affected by diseases. But we still don't know whether the different microbiomes cause disease, or are a result in the development of disease," he says.

11. Transferring bacteria from one gut to another can transfer disease—or maybe cure it.

"Studies in mice show that transplanting microbes from obese mice can transfer obesity to thin mice," Zaph says. But transplanting microbes from healthy people into sick people can be a powerful treatment for some intestinal infections, like that of the bacteria Clostridium difficile, he adds. Research is pouring out on how the microbiome affects various diseases, including multiple sclerosis, Parkinson's, and even autism.

12. The microbes in your intestines might influence how you respond to medical treatments.

Some people don't respond to cancer drugs as effectively as others, Zaph says. "One reason is that different microbiomes can metabolize the drugs differently." This has huge ramifications for chemotherapy and new cancer treatments called checkpoint inhibitors. As scientists learn more about how different bacteria metabolize drugs, they could possibly improve how effective existing cancer treatments are.

7 Facts About Blood

Moussa81/iStock via Getty Images
Moussa81/iStock via Getty Images

Everyone knows that when you get cut, you bleed—a result of the constant movement of blood through our bodies. But do you know all of the functions the circulatory system actually performs? Here are some surprising facts about human blood—and a few cringe-worthy theories that preceded the modern scientific understanding of this vital fluid.

1. Doctors still use bloodletting and leeches to treat diseases.

Ancient peoples knew the circulatory system was important to overall health. That may be one reason for bloodletting, the practice of cutting people to “cure” everything from cancer to infections to mental illness. For the better part of two millennia, it persisted as one of the most common medical procedures.

Hippocrates believed that illness was caused by an imbalance of four “humors”—blood, phlegm, black bile, and yellow bile. For centuries, doctors believed balance could be restored by removing excess blood, often by bloodletting or leeches. It didn’t always go so well. George Washington, for example, died soon after his physician treated a sore throat with bloodletting and a series of other agonizing procedures.

By the mid-19th century, bloodletting was on its way out, but it hasn’t completely disappeared. Bloodletting is an effective treatment for some rare conditions like hemochromatosis, a hereditary condition causing your body to absorb too much iron.

Leeches have also made a comeback in medicine. We now know that leech saliva contains substances with anti-inflammatory, antibiotic, and anesthetic properties. It also contains hirudin, an enzyme that prevents clotting. It lets more oxygenated blood into the wound, reducing swelling and helping to rebuild tiny blood vessels so that it can heal faster. That’s why leeches are still sometimes used in treating certain circulatory diseases, arthritis, and skin grafting, and helps reattach fingers and toes. (Contrary to popular belief, even the blood-sucking variety of leech is not all that interested in human blood.)

2. Scientists didn't understand how blood circulation worked until the 17th century.

William Harvey, an English physician, is generally credited with discovering and demonstrating the mechanics of circulation, though his work developed out of the cumulative body of research on the subject over centuries.

The prevailing theory in Harvey’s time was that the lungs, not the heart, moved blood through the body. In part by dissecting living animals and studying their still-beating hearts, Harvey was able to describe how the heart pumped blood through the body and how blood returned to the heart. He also showed how valves in veins helped control the flow of blood through the body. Harvey was ridiculed by many of his contemporaries, but his theories were ultimately vindicated.

3. Blood types were discovered in the early 20th century.

Austrian physician Karl Landsteiner discovered different blood groups in 1901, after he noticed that blood mixed from people with different types would clot. His subsequent research classified types A, B and O. (Later research identified an additional type, AB). Blood types are differentiated by the kinds of antigens—molecules that provoke an immune system reaction—that attach to red blood cells.

People with Type A blood have only A antigens attached to their red cells but have B antigens in their plasma. In those with Type B blood, the location of the antigens is reversed. Type O blood has neither A nor B antigens on red cells, but both are present in the plasma. And finally, Type AB has both A and B antigens on red cells but neither in plasma. But wait, there’s more! When a third antigen, called the Rh factor, is present, the blood type is classified as positive. When Rh factor is absent, the blood type is negative.

Scientists still don’t understand why humans have different blood types, but knowing yours is important: Some people have life-threatening reactions if they receive a blood type during a transfusion that doesn’t “mix” with their own. Before researchers developed reliable ways to detect blood types, that tended to turn out badly for people receiving an incompatible human (or animal!) blood transfusion.

4. Blood makes up about 8 percent of our total body weight.

Adult bodies contain about 5 liters (5.3 quarts) of blood. An exception is pregnant women, whose bodies can produce about 50 percent more blood to nourish a fetus.)

Plasma, the liquid portion of blood, accounts for about 3 liters. It carries red and white blood cells and platelets, which deliver oxygen to our cells, fight disease, and repair damaged vessels. These cells are joined by electrolytes, antibodies, vitamins, proteins, and other nutrients required to maintain all the other cells in the body.

5. A healthy red blood cell lasts for roughly 120 days.

Red blood cells contain an important protein called hemoglobin that delivers oxygen to all the other cells in our bodies. It also carries carbon dioxide from those cells back to the lungs.

Red blood cells are produced in bone marrow, but not everyone produces healthy ones. People with sickle cell anemia, a hereditary condition, develop malformed red blood cells that get stuck in blood vessels. These blood cells last about 10 to 20 days, which leads to a chronic shortage of red blood cells, often causing to pain, infection, and organ damage.

6. Blood might play a role in treating Alzheimer's disease.

In 2014, research led by Stanford University scientists found that injecting the plasma of young mice into older mice improved memory and learning. Their findings follow years of experiments in which scientists surgically joined the circulatory systems of old and young mice to test whether young blood could reverse signs of aging. Those results showed rejuvenating effects of a particular blood protein on the organs of older mice.

The Stanford team’s findings that young blood had positive effects on mouse memory and learning sparked intense interest in whether it could eventually lead to new treatments for Alzheimer’s disease and other age-related conditions.

7. The sight of blood can make people faint.

For 3 to 4 percent of people, squeamishness associated with blood, injury, or invasive medical procedures like injections rises to the level of a true phobia called blood injury injection phobia (BII). And most sufferers share a common reaction: fainting.

Most phobias cause an increase in heart rate and blood pressure, and often muscle tension, shakes, and sweating: part of the body’s sympathetic nervous system’s “fight or flight” response. But sufferers of BII experience an added symptom. After initially increasing, their blood pressure and heart rate will abruptly drop.

This reaction is caused by the vagus nerve, which works to keep a steady heart rate, among other things. But the vagus nerve sometimes overdoes it, pushing blood pressure and heart rate too low. (You may have experienced this phenomenon if you’ve ever felt faint while hungry, dehydrated, startled, or standing up too fast.) For people with BII, the vasovagal response can happen at the mere sight or suggestion of blood, needles, or bodily injury, making even a routine medical or dental checkup cause for dread and embarrassment.

What Purpose Does the Belly Button Serve?

misuma/iStock via Getty Images
misuma/iStock via Getty Images

While your eyelashes are protecting your eyes, your lungs are letting you breathe, and virtually every other part of your body—inside and out—is performing its own relatively well-known task, your belly button is just sitting there collecting lint. And while it’s true that your navel served its most important purpose before you were born, it’s not totally useless now.

According to ZME Science, back when you were a fetus, your belly button was more of a belly portal: Your umbilical cord extended from it and connected you to the placenta on your mother’s uterine wall. That way, the placenta could channel nutrients and oxygen to you through the cord, and you could send back waste.

Your umbilical cord was cut when you were born, creating a tiny bulge that left behind some scar tissue after it healed. That scar tissue is your belly button, navel, or umbilicus. Though you may have heard that the shape of your belly button is a direct result of the scissor skills of the doctor who delivered you, that’s not true. Dr. Dan Polk, a neonatologist in the Chicago area, told the Chicago Tribune that a belly button's shape “has to do with how much baby skin leads onto the umbilical cord from the baby’s body. Less skin makes an innie; more skin makes an outie.” About 90 percent of people have innies.

Regardless of how your belly button looks, you probably don’t use it on a daily basis. However, if you’ve studied anatomy, medicine, or a related field, you might recognize it as the central point by which the abdomen is divided into the following quadrants: right upper, left upper, right lower, and left lower. Another way of classifying that area is into nine regions—including the hypochondriac, lumbar, iliac, epigastric, and hypogastric regions—with the umbilical region at the very center.

Abdominopelvic regions diagram
Blausen Medical, Wikimedia Commons // CC BY 3.0

Your belly button can also serve as the opening for laparoscopic surgery, which can save you from having a scar elsewhere on your abdomen.

The navel is a great central landmark outside of medicine, too. If you’ve taken yoga or Pilates classes, you may have heard it referred to as the center of balance or center of gravity. Because it sits right on top of your abdominal muscles, your belly button is an easy marker for your instructor to mention when they want you to access your core, which helps you balance.

And, of course, belly buttons are notorious for storing quite a bit of lint, which always seems to be blue (you can learn more about that here).

Have you got a Big Question you'd like us to answer? If so, let us know by emailing us at bigquestions@mentalfloss.com.

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