Does Drinking Alcohol Kill Brain Cells?

iStock
iStock

Watch someone after they’ve had a few drinks, and you’ll find clear evidence that alcohol does something to their brain. They stumble, slur their words, lose control of their emotions, and forget things. 

Some people have tried to explain this behavior as the aftermath of cell death caused by alcohol. Often, it’s packaged as a neat factoid like “Three beers kill 10,000 brain cells.”

But is this true? No. But alcohol does damage some of your 86 billion brain cells, or neurons, which send electrical and chemical messages within the brain and between it and other parts of the body. 

Ethyl alcohol (the kind found in boozy beverages, also known as ethanol) can kill cells and microorganisms. That’s what makes it an effective antiseptic. Fortunately, when you drink alcoholic beverages, your body tries not to let all of that ethanol roam around unchecked. Enzymes in your liver convert it first info acetaldehyde (which is highly toxic) and then into acetate, which is broken down into water and carbon dioxide and eliminated by your body.

The liver can only work so fast, though, processing about 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of distilled spirits per hour. If you’re knocking drinks back fast enough that your liver can’t keep up, the excess alcohol hangs out in the blood and travels through the body until it can be processed. 

When this alcohol reaches the brain, it doesn’t kill the cells. What it does is inhibit the communication between dendrites, or branching connections at the ends of neurons that send and receive information between neurons, in the cerebellum, a part of the brain involved in motor coordination. This poor communication results in some of the typical impairments of intoxication. 

Researchers at Washington University in St. Louis found that alcohol, even when applied directly to neurons, didn’t kill them. It just interfered with the way they transmit information. Specifically, the researchers showed that alcohol causes certain receptors on neurons to manufacture steroids that inhibit memory formation. 

Some alcoholics can experience neuron death as part of a brain disorder called Wernicke-Korsakoff syndrome. In these cases, the evidence again suggests that the disease and cell death aren’t caused by the alcohol itself, but a B1 (or thiamine) deficiency and general malnutrition that often go hand in hand with alcoholism. 

For moderate drinkers, a number of studies from the last 15 years suggest that, far from killing brain cells, a little tipple is actually associated with a reduced risk of cognitive decline and dementia. 

Where Did the Phrase 'Red Herring' Come From?

iStock.com/Mathias Darmell
iStock.com/Mathias Darmell

You may have seen a red herring in a recent book or movie, but you probably only realized it after the fact. These misleading clues are designed to trick you into drawing an incorrect conclusion, and they're a popular ploy among storytellers of all stripes.

If you've seen or read the Harry Potter series—and really, who hasn’t?—then you may recall some of the many instances where J.K. Rowling employed this literary device. That endearing plot twist about the nature of Snape's character, for example, is likely one of the longest-running red herrings ever written.

Sometimes they aren't even subtle. Agatha Christie's murder mystery And Then There Were None directly mentions red herring in reference to a character's death, and a statue of a red herring appears in Lemony Snicket's A Series of Unfortunate Events. Perhaps most blatantly, a character in the cartoon A Pup Named Scooby-Doo who was constantly being blamed for myriad crimes was named—you guessed it—Red Herring.

But where does this literary device come from, and why is it named after a fish? For a bit of background: herring are naturally a silvery hue, but they turn reddish-brown when they're smoked. Long before refrigerators were invented, this was done to preserve the fish for months at a time. They can also be pretty smelly. As Gizmodo's io9 blog points out, it was believed that red herring were dragged against the ground to help train hounds to sniff out prey in the 17th century. Another theory was that escaped prisoners used the fish to cover their tracks and confuse the dogs that tailed them.

However, io9 notes that red herring were actually used to train horses rather than dogs, and only if the preferred choice—a dead cat—wasn't available. The idea was that the horses would get used to following the scent trail, which in turn would make them less likely to get spooked while "following the hounds amid the noise and bustle of a fox hunt," notes British etymologist and writer Michael Quinion, who researched the origin of the phrase red herring.

The actual origin of the figurative sense of the phrase can be traced back to the early 1800s. Around this time, English journalist William Cobbett wrote a presumably fictional story about how he had used red herring as a boy to throw hounds off the scent of a hare. He elaborated on this anecdote and used it to criticize some of his fellow journalists. "He used the story as a metaphor to decry the press, which had allowed itself to be misled by false information about a supposed defeat of Napoleon," Quinion writes in a blog. "This caused them to take their attention off important domestic matters."

According to Quinion, an extended version of this story was printed in 1833, and the idiom spread from there. Although many people are more familiar with red herrings in pop culture, they also crop up in political spheres and debates of all kinds. Robert J. Gula, the author of Nonsense: Red Herrings, Straw Men and Sacred Cows: How We Abuse Logic in Our Everyday Language, defines a red herring as "a detail or remark inserted into a discussion, either intentionally or unintentionally, that sidetracks the discussion."

The goal is to distract the listener or opponent from the original topic, and it's considered a type of flawed reasoning—or, more fancifully, a logical fallacy. This application of red herring seems to be more in line with its original usage, but as Quinion notes: "This does nothing to change the sense of red herring, of course: it's been for too long a fixed part of our vocabulary for it to change. But at least we now know its origin. Another obscure etymology has been nailed down."

What Is the Shelf Life of Donated Eyes?

iStock.com/Pedro_Turrini
iStock.com/Pedro_Turrini

Zoe-Anne Barcellos:

I can only answer for cornea and eye donation.

The FDA does all oversight (no pun intended) of organ disposition.

The main organs—heart, liver, pancreas, lungs, etc.—are transplanted within hours. They are just not viable if they are not being perfused constantly.

The other tissues—like bone, skin, tendons, etc.—do not need to be transplanted immediately. But I am not sure on the regulations of when they need to be transplanted.

With the eyes, there are four tissues that can be recovered.

We recover whole eyes for research and education purposes. These usually go much faster, but we can hold them up to a year.

Conjunctiva can also be recovered; conjunctiva is a clear covering over most of the eye (it is what gets irritated when you have pink eye). I have been working as a recovery tech for five years, and our office has not had a request for "conj" in all that time. I believe it is mostly used for research, but I could be wrong.

Sclera is the white area of your eye. It is fairly thick and flexible. If you have ever touched a reptile egg, that is what it reminds me of. We recover sclera for transplant. They use it for several things, but mainly to patch punctures. Similar to if you pop the inner tube of your bike and repair it. Sclera can also be used to repair ear drums. We can hold on to this for up to a year.

The main thing we recover is corneas. In the U.S., we must transplant these within seven days of recovery. (Recovery is usually within hours of death, but we can push it up to 20 hours after if needed.) Sometimes we have more corneas than we need, and then they are shipped overseas and transplanted up to 14 days after recovery. There is no real different outcome with the later transplant time, but the FDA in the U.S. made the rules. (You can sign up to be an organ, tissue, and eye donor here.)

This post originally appeared on Quora. Click here to view.

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