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8 Common Misconceptions About Antidepressants

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Think you have depression, but feeling uncomfortable about the idea of treating it with medication? Each person’s treatment plan is unique, but if you feel like your life could be improved by antidepressants, you shouldn’t let the many common myths and misconceptions surrounding their use keep you from seeking the help you need.

Mental Floss spoke with Dr. David Mischoulon, director of research at Massachusetts General Hospital's Depression Clinical and Research Program, who set the record straight on some common misconceptions about antidepressants.

1. THE MYTH: ANTIDEPRESSANTS DON'T ADDRESS THE ROOT CAUSE OF DEPRESSION.

There are multiple factors that can contribute to depression, ranging from environmental or situational components to brain biochemistry. Medication can help when the underlying cause is partly biological in nature.

“For example, there are some people who may develop depression for no apparent reason,” Dr. Mischoulon says. “There is absolutely no particular stress in their lives. There hasn’t been any misfortune of any sort. In fact, they’ll often say, ‘I’ve got a life that most of the world would envy,’ and yet they’re depressed ... Those people often respond very well to antidepressants, and in that sense, [the medicine] is getting at the root cause [of the depression], which is a biochemical imbalance in the brain.”

At the other end of the spectrum, some people “may become depressed primarily because of situational problems,” Mischoulon adds. "They may be experiencing problems in the workplace, family problems, or a divorce, things like that. Those factors can certainly contribute to depression—perhaps in combination with a proclivity to becoming depressed, or because … the stress is just so, so tremendous that the person becomes depressed as a result.”

Sometimes these individuals may not respond to antidepressants because the root cause is situational. If their situations were to improve—say, they got a better job—they might start feeling better. Therapy might also help them develop better coping skills.

“There are certain kinds of therapies that have been carefully studied in clinical trials, and for many [depression] cases, they can work very well,” Mischoulon says. “For example, cognitive behavioral therapy is one of the better studied forms; it’s been shown in some studies to be as effective as antidepressants.”

That said, research also suggests that for many people, treating depression with a combination of therapy and medication can be the best course of treatment. “The two will work synergistically," Mischoulon explains. "By combining the two you can get a better result.” (If you're thinking about beginning therapy, here's a guide to figuring out which type is best for you.)

Mental health researchers are trying to pinpoint ways to differentiate between a biochemical depression and situational depression. But as of right now, "we’re not at a point where we can use what we've learned in a clinical setting," Mischoulon says.

2. THE MYTH: ANTIDEPRESSANTS ARE "HAPPY PILLS."

“If I give an antidepressant to a healthy individual—someone who’s not depressed—they’re not going to be happier, or more cheerful” as a result of taking it, Mischoulon says. “It only works to return the mood to the patient’s normal baseline. So if you’re depressed, the antidepressant can help you get back to where you were.”

3. THE MYTH: ANTIDEPRESSANTS ARE ADDICTIVE.

Antidepressants “aren’t drugs of abuse,” Mischoulon says. They may improve your depression symptoms, which can lead to increased energy levels and an improved mood, but they won’t get you high or make you crave additional or stronger doses—all hallmarks of addiction.

However, since your body grows accustomed to the drug, you may experience withdrawal syndromes—including headaches, dizziness, nausea, and irritability—if you stop taking it abruptly, “similarly to what you might have with a recreational drug,” Mischoulon explains. If you’re thinking about discontinuing an antidepressant, check with your doctor first. He or she will likely recommend that you taper your dosage over a period of days or weeks, depending on the medication.

4. THE MYTH: ANTIDEPRESSANTS WILL PERMANENTLY ALTER YOUR PERSONALITY.

Taking the right antidepressant can slowly help a depressed person return to his or her baseline mood, making them feel and act more like “themselves." That said, Mischoulon does say that some patients on antidepressants “report being emotionally numbed, like they can’t experience normal emotions.” There aren’t many prospective or systematic studies that examine this phenomenon, but Mischoulon estimates that maybe 10 percent of the patients in his practice have reported it. It's "a relatively small minority," he adds. 

If this happens to you, don’t worry: It’s usually "not a known cause for concern,” Mischoulon says. This won’t “cause permanent damage to someone’s personality, or their capacity to feel emotions … It’s simply a matter of discontinuing the antidepressant and trying another one.”

5. THE MYTH: ANTIDEPRESSANTS ARE A SHORT-TERM FIX.

If you were successfully treated with antidepressants, you may want to speak with your doctor about continuing to take them as a preventative measure, even if you now feel fine. Research shows that experiencing just one episode of depression puts a person at a 50 percent risk for experiencing another episode, and increases their chances for future relapse.

Some doctors suggest treating conditions like major depression in the same way that you would a chronic illness—with lifelong management. “The good thing is that most antidepressants are very safe to take over the long term, so if a person had to take one indefinitely, it’s not the worst thing in the world,” Mischoulon says.

That said, if you’ve responded well to treatment and don’t have a prior history of depressive episodes, there’s a chance that you’ll be OK if you come off them under a doctor’s supervision.

6. THE MYTH: IF YOU TRY ONE ANTIDEPRESSANT AND IT DOESN'T WORK, MEDICATION ISN'T FOR YOU.

Once you begin taking an antidepressant, it can take weeks, if not months, to feel the full effects. And since there’s currently no good way to predict which antidepressant will work for any one individual, there’s always the chance that the one you’re trying may end up not being the right one for you. If this ends up being the case, you’ll have to begin the cycle anew—this time, with a different pill.

This trial-and-error process can be discouraging for some patients. Keep in mind, however, that there are more than two dozen antidepressants on the market—meaning there’s a good chance you’ll find something that alleviates your symptoms.

“There are antidepressants from different families that differ biochemically,” Mischoulon explains. “What we find is that a lot of people will take a particular type of antidepressant and it may not work, and then they’ll try an antidepressant from another family, and that one will work better for them.”

7. THE MYTH: ALL ANTIDEPRESSANTS HAVE AWFUL, LONG-LASTING SIDE EFFECTS.

From insomnia to blurred vision to fatigue, the long checklist of potential side effects included in your medicine packet can be intimidating, if not downright frightening. Don’t worry: The likelihood that you’ll experience every single one of them is slim, Mischoulon says. Most people only encounter one or two; common side effects include upset stomach, headaches, weight gain, and sedation, but side effects vary from one medication to the next. (For example, on average, Mischoulon estimates that about 15 percent of his patients report weight gain.)

These side effects are sometimes short-term, popping up during the initial stages of treatment and tapering off as the patient’s body gets used to the medication. Still, in other cases, they persist. In the latter instance, you may want to talk with your doctor about switching to another medication or the best way to treat your side effects.

8. THE MYTH: DOCTORS OVERTREAT AMERICANS FOR DEPRESSION.

According to the National Center for Health Statistics, antidepressants were the third most commonly prescribed drug taken by Americans of all ages between 2005 and 2008. (Though not all patients take antidepressants for depression and anxiety; they can also be used to treat other issues, including insomnia and chronic pain.) Are these medications overprescribed to patients?

“I think in certain circles they may be overprescribed, and in others they may be underprescribed,” Mischoulon says. “What we do know is that there are a lot of people with depression out there who are not being adequately treated … This could apply to antidepressants, as well as psychotherapy. A lot of people are not getting treatment at all who should be getting some treatment.”

People with depression don’t receive care for a variety of reasons, Mischoulon points out: Stigma, a lack of education, limited economic resources, or not living near a health care professional for treatment are just a few examples. That said, there can be dire repercussions for those who don't seek treatment, including suicide and worsened outcomes for concurrent medical conditions, like cardiovascular disease.

If you think you have depression and have the means to see a doctor, "get a professional evaluation," Mischoulon advises. "Don’t try to self-diagnose. Don’t try to treat it yourself with over-the-counter supplements. Speak to your primary care doctor, and maybe speak to a psychiatrist ... If not treated properly, depression can have devastating consequences."

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9 Facts about Physicist Michael Faraday, the 'Father of Electricity'
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A self-taught scientist, Michael Faraday (1791-1867) excelled in chemistry and physics to become one of the most influential thinkers in history. He’s been called the "father of electricity," (Nikola Tesla and Thomas Edison also wear that crown) and his appetite for experimenting knew no bounds. "Nothing is too wonderful to be true, if it be consistent with the laws of nature; and in such things as these, experiment is the best test of such consistency," he wrote. Faraday discovered laws of electromagnetism, invented the first electric motor, and built the first electric generator—paving the way for our mechanized age. Read on for more Faraday facts.

1. HE NEVER HAD A FORMAL SCIENTIFIC EDUCATION.

Born in south London in a working-class family, Faraday earned a rudimentary education in reading, writing, and math. When he turned 14 he was apprenticed to a London bookbinder for the following seven years. In his free time, Faraday read Jane Marcet's Conversations in Chemistry, an 1806 bestseller that explained scientific topics for a general audience.

2. HE WAS A SELF-STARTER.

Like Marcet, Faraday was fascinated by the work of Sir Humphry Davy, a charismatic chemist who had found fame by testing the effects of nitrous oxide on himself. (He let others, including poet Samuel Taylor Coleridge, inhale the gas on the condition that they keep diaries of their thoughts and sensations while high.) In spring 1812, a customer at the bookbindery gave Faraday tickets to see Davy’s upcoming lectures. Faraday compiled his notes from the lectures in a bound volume (the one benefit of his toil at the bookbinder's) and sent the book to Davy, requesting to become his assistant—an unheard-of notion for a tradesman with no university degree. Sensing his intelligence and drive, Davy secured him a job at the Royal Institution, where Davy ran the chemistry lab.

3. HE INVENTED A MOTOR WITH MAGNETS AND MERCURY.

By 1820, other scientists had shown that an electric current produces a magnetic field, and that two electrified wires produce a force on each other. Faraday thought there could be a way to harness these forces in a mechanical apparatus. In 1822, he built a device using a magnet, liquid mercury (which conducts electricity) and a current-carrying wire that turned electrical energy into mechanical energy—in other words, the first electric motor. Faraday noted the success in his journal [PDF]: "Very satisfactory, but make more sensible apparatus."

4. HE ALSO CREATED THE FIRST ELECTRIC GENERATOR.

A decade after his breakthrough with the motor, Faraday discovered that the movement of a wire through a stationary magnetic field can induce an electrical current in the wire—the principle of electromagnetic induction. To demonstrate it, Faraday built a machine in which a copper disc rotated between the two poles of a horseshoe magnet, producing its own power. The machine, later called the Faraday disc, became the first electric generator.

5. HE SHOWED THE PULL OF MAGNETIC FORCE.

In a brilliantly simple experiment (recreated by countless schoolchildren today), Faraday laid a bar magnet on a table and covered it with a piece of stiff paper. Then he sprinkled magnetized iron shavings across the paper, which immediately arranged themselves into semicircular arcs emanating from the ends—the north and south poles—of the magnet. In addition to revealing that magnets still exert pull through barriers, he visualized the pattern of magnetic force in space.

6. YOU CAN VISIT HIS MAGNETIC LABORATORY IN LONDON.

Faraday served in a number of scientific roles at the Royal Institution, an organization dedicated to promoting applied science. Eventually Faraday was appointed as its Fullerian Professor of Chemistry, a permanent position that allowed him to research and experiment to his heart's content. His magnetic laboratory from the 1850s is now faithfully replicated in the Royal Institution's Faraday Museum. It displays many of his world-changing gadgets, including an original Faraday disc, one of his early electrostatic generators, his chemical samples, and a giant magnet.

7. HE POPULARIZED NEW SCIENTIFIC TERMINOLOGY.

Faraday's work was so groundbreaking that no descriptors existed for many of his discoveries. With his fellow scientist William Whewell, Faraday coined a number of futuristic-sounding names for the forces and concepts he identified, such as electrode, anode, cathode, and ion. (Whewell himself coined the word "scientist" in 1834, after "natural philosopher" had become too vague to describe people working in increasingly specialized fields.)

8. PRINCE ALBERT GAVE HIM SOME SWEET REAL ESTATE.

In 1848, the Prince Consort, also known as Queen Victoria's husband Prince Albert, gave Faraday and his family a comfortable home at Hampton Court—not the royal palace, but near it—free of charge, to recognize his contributions to science. The house at 37 Hampton Court Road was renamed Faraday House until he died there on August 25, 1867. Now it's known simply by its street address.

9. HE WAS FEATURED ON THE UNITED KINGDOM'S £20 NOTE.

To honor Faraday's role in the advancement of British science, the Bank of England unveiled a £20 bill with his portrait on June 5, 1991. He joined an illustrious group of Britons with their own notes, including William Shakespeare, Florence Nightingale, and Isaac Newton. By the time it was withdrawn in February 2001, the bank estimated that about 120 million Faraday bills were in circulation (that's more than 2 billion quid).

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4 Expert Tips on How to Get the Most Out of August's Total Solar Eclipse
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As you might have heard, there’s a total solar eclipse crossing the U.S. on August 21. It’s the first total solar eclipse in the country since 1979, and the first coast-to-coast event since June 8, 1918, when eclipse coverage pushed World War I off the front page of national newspapers. Americans are just as excited today: Thousands are hitting the road to stake out prime spots for watching the last cross-country total solar eclipse until 2045. We’ve asked experts for tips on getting the most out of this celestial spectacle.

1. DON’T FRY YOUR EYES—OR BREAK THE BANK

To see the partial phases of the eclipse, you will need eclipse glasses because—surprise!—staring directly at the sun for even a minute or two will permanently damage your retinas. Make sure the glasses you buy meet the ISO 12312-2 safety standards. As eclipse frenzy nears its peak, shady retailers are selling knock-off glasses that will not adequately protect your eyes. The American Astronomical Society keeps a list of reputable vendors, but as a rule, if you can see anything other than the sun through your glasses, they might be bogus. There’s no need to splurge, however: You can order safe paper specs in bulk for as little as 90 cents each. In a pinch, you and your friends can take turns watching the partial phases through a shared pair of glasses. As eclipse chaser and author Kate Russo points out, “you only need to view occasionally—no need to sit and stare with them on the whole time.”

2. DON’T DIY YOUR EYE PROTECTION

There are plenty of urban legends about “alternative” ways to protect your eyes while watching a solar eclipse: smoked glass, CDs, several pairs of sunglasses stacked on top of each other. None works. If you’re feeling crafty, or don’t have a pair of safe eclipse glasses, you can use a pinhole projector to indirectly watch the eclipse. NASA produced a how-to video to walk you through it.

3. GET TO THE PATH OF TOTALITY

Bryan Brewer, who published a guidebook for solar eclipses, tells Mental Floss the difference between seeing a partial solar eclipse and a total solar eclipse is “like the difference between standing right outside the arena and being inside watching the game.”

During totality, observers can take off their glasses and look up at the blocked-out sun—and around at their eerily twilit surroundings. Kate Russo’s advice: Don’t just stare at the sun. “You need to make sure you look above you, and around you as well so you can notice the changes that are happening,” she says. For a brief moment, stars will appear next to the sun and animals will begin their nighttime routines. Once you’ve taken in the scenery, you can use a telescope or a pair of binoculars to get a close look at the tendrils of flame that make up the sun’s corona.

Only a 70-mile-wide band of the country stretching from Oregon to South Carolina will experience the total eclipse. Rooms in the path of totality are reportedly going for as much as $1000 a night, and news outlets across the country have raised the specter of traffic armageddon. But if you can find a ride and a room, you'll be in good shape for witnessing the spectacle.

4. PRESERVE YOUR NIGHT VISION

Your eyes need half an hour to fully adjust to darkness, but the total eclipse will last less than three minutes. If you’ve just been staring at the sun through the partial phases of the eclipse, your view of the corona during totality will be obscured by lousy night vision and annoying green afterimages. Eclipse chaser James McClean—who has trekked from Svalbard to Java to watch the moon blot out the sun—made this rookie mistake during one of his early eclipse sightings in Egypt in 2006. After watching the partial phases, with stray beams of sunlight reflecting into his eyes from the glittering sand and sea, McClean was snowblind throughout the totality.

Now he swears by a new method: blindfolding himself throughout the first phases of the eclipse to maximize his experience of the totality. He says he doesn’t mind “skipping the previews if it means getting a better view of the film.” Afterward, he pops on some eye protection to see the partial phases of the eclipse as the moon pulls away from the sun. If you do blindfold yourself, just remember to set an alarm for the time when the total eclipse begins so you don’t miss its cross-country journey. You'll have to wait 28 years for your next chance.

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