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Scientists Find Non-Gluten Cause of Wheat Sensitivity

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Researchers presenting at the 2016 United European Gastroenterology conference have identified a group of non-gluten proteins that can trigger symptoms of asthma, multiple sclerosis, chronic pain, and more. 

Gluten-free diets began as a necessity for people with celiac disease, in which violent immune reactions to wheat can cause intestinal damage, widespread inflammation, and trouble absorbing nutrients. Then the food and diet industries caught on, and suddenly a gluten-free diet was being touted as the way to lose weight, flush “toxins,” and improve everything from mental clarity to libido. An Us-Against-Them narrative emerged in the media, pitting people with an autoimmune condition against all the fools pointlessly avoiding wheat. 

This bizarre, invented binary initially overlooked a third group of gluten-free eaters: people without celiac disease who still felt that wheat made them sick. Then that group began to grow and became harder to ignore—but rather than being taken seriously about their health, these folks were classed as a subtype of fool. “You’re either allergic to gluten or you’re just being a diva,” the argument went. 

But bit by bit, vindication has come creeping in. This July, an international team of researchers found that people with self-reported non-celiac wheat sensitivity (NCWS) were indeed sickened by eating wheat. Their intestinal lining was damaged, and blood tests showed higher levels of systemic inflammation. Gluten or no, something was messing them up. 

Another group of researchers suspected that something might be another protein. They started looking at a group called amylase-trypsin inhibitors, or ATIs. The ATIs are a small group, representing about 4 percent of wheat proteins, but they’re powerful.

The scientists found that consuming pure ATIs can cause all manner of nasty reactions throughout the body, triggering inflammation not just in the gut but also in the lymph nodes, kidneys, spleen, and brain. That same inflammation can exacerbate autoimmune conditions like rheumatoid arthritis, multiple sclerosis, asthma, lupus, and inflammatory bowel disease. 

Lead researcher Detlef Schuppan of Johannes Gutenberg University in Germany says ATI and gluten produce similar but distinct reactions in the human body. “ATIs from wheat that are also contaminating commercial gluten activate specific types of immune cells in the gut and other tissues,” he said in a statement, “thereby potentially worsening the symptoms of pre-existing inflammatory illnesses.”

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Little Baby's Ice Cream
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Pizza and Cricket Cake Are Just Some of the Odd Flavors You'll Find at This Philadelphia Ice Cream Shop
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Little Baby's Ice Cream

Ice cream flavors can get pretty out-there, thanks to the growing number of creative scoop shops willing to take risks and broaden their customers’ horizons beyond chocolate, vanilla, and strawberry. Intrepid foodies can cool off with frozen treats that taste like horseradish, foie gras, and avocado, while Philadelphia's Little Baby’s Ice Cream is pushing the boundaries of taste with chilly offerings like everything bagel, Maryland BBQ, ranch, and cricket cake.

Cricket-flavored ice cream, created by Philadelphia-based Little Baby's Ice Cream
Little Baby's Ice Cream

Everything Bagel-flavored ice cream, created by Philadelphia-based Little Baby's Ice Cream
Little Baby's Ice Cream

As Lonely Planet News reports, Little Baby’s Ice Cream launched its first signature “oddball” ice cream—Earl Grey sriracha—in 2011. Since then, its rotating menu has only gotten quirkier. In addition to the aforementioned flavors, customers who swing by Little Baby’s this summer can even try pizza ice cream.

The store created the savory flavor in 2011, to celebrate neighborhood eatery Pizza Brain’s inclusion into Guinness World Records for its vast collection of pizza memorabilia. The savory, Italian-esque snack is made from ingredients like tomato, basil, oregano, salt, and garlic—and yes, it actually tastes like pizza, Little Baby’s co-owner Pete Angevine told Lonely Planet News.

Pizza-flavored ice cream, made by Philadelphia-based Little Baby's Ice Cream
Little Baby's Ice Cream

“Frequently, folks will see it on the menu and be incredulous, then be convinced to taste it, giggle, talk about how surprised they are that it really tastes just like pizza … and then order something else,” Angevine said. “That’s just fine. Just as often though, they’ll end up getting a pizza milkshake!”

Little Baby’s flagship location is in Philadelphia's East Kensington neighborhood, but customers can also sample their unconventional goods at additional outposts in West Philadelphia, Baltimore, and a pop-up stand in Washington, D.C.’s Union Market. Just make sure to bring along a sense of adventure, and to leave your preconceived notions of what ice cream should taste like at home.

[h/t Lonely Planet]

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11 of the Most Extreme Junk Foods Ever Created
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It should come as no surprise that National Junk Food Day is traditionally celebrated on July 21—smack dab in the middle of the dog days of summer, when the streets run thick with ice cream trucks and county fairs boast the kind of fried treats that can only be described as “awesome” (both in the modern sense and the more dated, whoa, we are in awe of that usage). But National Junk Food Day shouldn’t be celebrated with commonplace junk food; oh, no, it deserves something far bigger and better. So save your potato chips and chocolate bars for another day, and get ready to try some truly wild treats.

1. THE KFC DOUBLE DOWN

KFC

Perhaps the most unexpectedly clever way to create a new extreme junk food item is to turn a non-junky foodstuff into something that just oozes calories and decadence. Fried chicken giant KFC knew that—and played it up to major effect—when they introduced the KFC Double Down to America back in 2010. The sandwich foregoes the most traditional aspect of any sandwich (the bread!) and substitutes two fried chicken filets. In between the two pieces of chicken? Bacon, two different kinds of cheese, and the Colonel’s “secret sauce.” There’s no room for a bun here, folks.

2. PIZZA HUT'S HOT DOG STUFFED CRUST PIZZA

Pizza Hut

We may associate items like fast food pizza and hot dog-stuffed anything with all-American palates, but cheesy juggernaut Pizza Hut saw things a bit differently. In 2012, the chain introduced a pizza with a hot dog-stuffed crust to our neighbors across the pond, treating their UK customers to the kind of taste sensation some people might have had literal nightmares about. Is it a pizza? Is it a hot dog? Somehow, it’s both—and yet something much more.

3. FRIENDLY'S GRILLED CHEESE BURGERMELT

Friendly's

Once again, a wily restaurant chain took a normal food item—in this case, a hamburger—and amped up its junk factor by doing away with something as commonplace as buns, in favor of an entirely different (and, yes, very junky) item. In 2010, Friendly’s rolled out its very own spin on the Double Down, slamming a regular old burger between not one, but two grilled cheese sandwiches. Who needs buns when you can have four pieces of bread, gooey cheese, and unfathomable amounts of butter?

4. GUY FIERI'S CHEESECAKE CHALLENGE

Whiz-bang chef Guy Fieri has long drawn ire for his more wild culinary creations, but what sets his cuisine apart from that of other junk food aficionados is his steadfast dedication to the key elements of any extreme item: size and odd combinations. Fieri’s “Guy's Cheesecake Challenge” is currently on the menu of his Vegas Kitchen and Bar, but it’s easy enough to replicate at home: Just halve a cheesecake, throw it on a plate, and douse liberally with hot fudge, pretzels, and potato chips. (What, no bacon?)

5. DENNY'S FRIED CHEESE MELT

Denny's

In August 2010, Denny’s introduced the Fried Cheese Melt, a grilled cheese sandwich stuffed with fried mozzarella sticks. Yes, it was served with both French fries and a side of marinara sauce, because it’s important to eat vegetables with every meal.

6. DUNKIN' DONUTS'S GLAZED DONUT BREAKFAST SANDWICH

Dunkin' Donuts

If you’ve ever hit up your local Dunkin' Donuts for breakfast and found yourself stumped when it came time to decide if you wanted a donut or a breakfast sandwich to get your morning motor revving, Dunkin' Donuts came up with a brilliant culinary brainstorm in 2013: the fast food favorite unveiled a breakfast sandwich that used glazed donuts as “bread,” wrapped around bacon and peppered egg.

7. JACK IN THE BOX MUNCHIE MEAL

Jack in the Box
What Jack’s Munchie Meals lack in creativity, they more than make up for in pure, unadulterated size and content. Each Munchie Meal—there are four total—features a massive sandwich (from the Stacked Grilled Cheese Burger to the Spicy Nacho Chicken Sandwich, and all sorts of wild fried things in between) accompanied with two beef tacos, “Halfsies” (a combo of fries and curly fries), and a 20-ounce fountain drink. These intense snack boxes are still available at most Jack in the Box locations, but you’ll have to wait until after 9 p.m. to procure your very own.

8. PIZZA HUT CHEESY BITES REMIX PIZZA

Apparently, there’s nothing that Pizza Hut loves more than using its crust as a delivery system for other junk food items. The hut that pizza built may have crammed hot dogs and hamburgers on to their pie sides, but there was something special about the Cheesy Bites Remix pizza. It featured fried cheese pockets stuffed with three different varieties of extra junk, from spicy seasoning to cream cheese and sesame to mozzarella and parmesan.

9. DEEP FRIED BUTTER

County and state fairs have long been hotbeds (sizzling, oily hotbeds) of wild, deep-frying invention. Dunking things in batter and then tossing them into a vat of oil is a nifty way to turn almost anything into a delicious crisp pocket of junky decadence, perfect for utensil-free eating—but that doesn’t mean that everything needs to get the deep-fried treatment. While deep-fried Oreos may be a stroke of brilliance, deep fried butter is just plain madness. Here’s a quick test: If you wouldn’t eat something if it weren’t deep-fried, don’t eat it if it is deep-fried. When was the last time you ate an entire stick of butter? See? Point proven.

10. THE BACON BUN BURGER

Not content to have a bacon sandwich between two chicken filets? Is a grilled cheese bun replacement not for you? Then try making your very own hamburger buns out of bacon. Carbs are bad for you, right?

11. FRIED ICE CREAM SANDWICH

The Florida State Fair is the proud home of the first fried ice cream sandwich, a junky treat that bears a name that doesn’t even begin to explain what it holds between its buns. It’s not a fried ice cream sandwich so much as a bacon cheeseburger (technically a sandwich) topped with a ball of fried ice cream. It might be a good meal for multi-taskers—no need to worry about dessert—but it doesn’t sound like the kind of thing good for anything else.

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