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ThinkGeek
ThinkGeek

The Mr. Meeseeks' Box-O'-Fun Game Recreates All the Stress of the Rick and Morty Episode

ThinkGeek
ThinkGeek

Fans of the Adult Swim cartoon Rick and Morty are likely well aware of the Meeseeks Box and the troubles that come with it. ThinkGeek decided to create a game based on the box, which captures all the original stress and repetition from the season one episode, "Meeseeks and Destroy."

As a quick refresher, the Meeseeks Box was a gift from Rick to the Smith family. When the button on top was pushed, a blue figure emerged to help solve any problem the user was having. When the task was completed, the Mr. Meeseeks ceased to exist. The trouble only starts when the user fails to complete their goal. As the Mr. Meeseeks explains, "We are created to serve a singular purpose for which we will go to any lengths to fulfill! Existence is pain to a Meeseeks, Jerry!"

In the Rick and Morty Mr. Meeseeks’ Box-O’-Fun, the game follows a similar narrative. To begin, the player pulls a card with a specific task on it. The player then rolls the dice and tries to get a number that matches the number on the card. If they fail, they must press the button and summon a Mr. Meeseeks. Each blue character can either help with the task or make it even harder to complete. Players can keep drawing cards until the request is complete or opt to complete a dare. 

The set comes with 24 dice, 35 request cards, 60 dare cards, 50 Mr. Meeseeks cards, a timer, and a button voiced by Justin Roiland. You can order the game at ThinkGeek for $40

[h/t The Daily Dot]

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Cell Free Technology
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technology
This Pixel Kit Will Let You Play Tetris With Jellyfish DNA
Cell Free Technology
Cell Free Technology

Forget playing Tetris on your phone. Now you can play it with jellyfish DNA. Bixels is a DIY game kit that lets you code your own games using synthetic biology, lighting up a digital display with the help of DNA.

Its 8-by-8 pixel grid is programmed to turn on with the help of the same protein that makes jellyfish glow, called green fluorescent protein (GFP). But you can program it to do more than just passively shine. You can use your phone and the associated app to excite Bixels' fluorescent proteins and make them glow at different frequencies, producing red, blue, and green colors. Essentially, you can program it like you would any computer, but instead of electronics powering the system, it's DNA.

Two blue boxes hold Bixel pixel grids.

Researchers use green fluorescent protein all the time in lab experiments as an imaging agent to illuminate biological processes for study. With Bixels, all you need is a little programming to turn the colorful lights (tubes filled with GFP) into custom images or interactive games like Tetris or Snake. You can also use it to develop your own scientific experiments. (For experiment ideas, Bixels' creator, the Irish company Cell-Free Technology, suggests the curricula from BioBuilder.)

A screenshot shows a user assembling a Bixel kit on video.

A pixel kit is housed in a cardboard box that looks like a Game Boy.

Bixels is designed to be used by people with all levels of scientific knowledge, helping make the world of biotechnology more accessible to the public. Eventually, Cell-Free Technology wants to create a bio-computer even more advanced than Bixels. "Our ultimate goal is to build a personal bio-computer which, unlike current wearable devices, truly interacts with our bodies," co-founder Helene Steiner said in a press release.

Bixels - Play tetris with DNA from Cell-Free Technology on Vimeo.

You can buy your own Bixel kit on Kickstarter for roughly $118. It's expected to ship in May 2018.

All images courtesy Cell-Free Technology

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Habibou Kouyate, Stringer, Getty Images
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science
Play a Game to Help Scientists Defeat a Cancer-Causing Toxin
Habibou Kouyate, Stringer, Getty Images
Habibou Kouyate, Stringer, Getty Images

If you're used to fighting virtual zombies or flying spaceships on your computer, a new series of games available on Foldit may sound a little unconventional. The object of the Aflatoxin Challenge is to rearrange protein structures and create new enzymes. But its impact on the real world could make it the most important game you've ever played: The scientists behind it hope it will lead to a new way to fight one of the most ruthless causes of liver cancer.

As Fast Company reports, the citizen science project is a collaboration between Mars, Inc. and U.C. Davis, the University of Washington, the Partnership for Aflatoxin Control in Africa, and Thermo Fisher Scientific. The team's online puzzles, which debuted on Foldit earlier this month, invite the public to create a new enzyme capable of finding and destroying carcinogens known as aflatoxins.

Aflatoxins form when certain fungi grow on crops like corn, nuts, and grains. Developing countries often don't have the resources to detect it in food, leaving around 4.5 billion people vulnerable to it. When people do eat food with high aflatoxin levels unknowingly, they can contract liver cancer. Roughly a quarter of all liver cancer cases around the world can be traced back to aflatoxin exposure.

The toxin's connection to agriculture is why the food giant Mars is so interested in fighting it. By working on a way to stop aflatoxins on a molecular level, the company could prevent its spread more efficiently than they would with less direct methods like planting drought-resistant crops or removing mold by hand.

The easiest way for scientists to eradicate an aflatoxin before it causes real harm is by making an enzyme that does the work for them. With the Aflatoxin Challenge, the hope is that by manipulating protein structures, online players will come up with an enzyme that attacks aflatoxins at a susceptible portion of their molecular structure called a lactone ring. Destroying the lactone ring makes aflatoxin much less toxic and essentially safe to eat.

The University of Washington launched Foldit in 2008. Since then, the online puzzle platform has been used to study a wide range of diseases including AIDS and Chikungunya. Everyone is welcome to contribute to the Foldit's new aflatoxin project for the next several weeks or so, after which scientists will synthesize genes based on the most impressive results to be used in future studies.

[h/t Fast Company]

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