The Difference Between Tylenol, Aspirin, Advil, and Aleve

Mario Tama/Getty Images
Mario Tama/Getty Images

It’s the morning after a wild night out. You stumble to the medicine cabinet and stare blearily at the array of over-the-counter painkillers, wondering which one will bring the quickest relief (and why all the labels have to be so darn bright). Fortunately, you’ve taped this article to the cabinet door, and instead of guessing, you can just check our handy guide below.

TYLENOL (ACETAMINOPHEN)

There are two main types of non-prescription painkillers: acetaminophen and non-steroidal anti-inflammatory drugs (NSAIDs), which includes basically everything that is not acetaminophen. Acetaminophen is the most popular pain-relieving option the world over, and it works by encouraging the brain to stop sending pain signals. 

Best for: Headaches and muscle aches

Not great for: Inflammation and joint pain

Watch out for: Taking too much acetaminophen, or mixing acetaminophen and alcohol, can lead to liver damage, and acetominophen is one of the drugs most frequently involved in overdose. Check the bottle to find out the maximum safe dose, and take it seriously.

ASPIRIN (ACETYLSALICYLIC ACID)

Aspirin and other NSAIDs work by decreasing your body’s production of enzymes that create pain-related chemicals. When prescribed by a doctor and taken every day, a small dose of aspirin can help lower the risk of heart attack or stroke for some people.

Best for: Reducing cardiovascular risk

Not great for: Intense pain  

Watch out for: Aspirin can be hard on the gut, liver, and kidney. Talk to your doctor to find out if it’s safe for you. Use caution when giving aspirin to children.

ADVIL AND MOTRIN (IBUPROFEN)

Ibuprofen is a pretty versatile drug, with the power to help with a broad range of aches, pains, and other complaints. 

Best for: Hangover (there you go!), menstrual cramps, sore or injured muscles, sinus pain, earaches, and toothaches

Not great for: Chronic headache

Watch out for: Ibuprofen carries most of the same risks as aspirin but is often available in higher doses, which can be even harder on your body. It’s also fast-acting and fast-fading, which might lead to more frequent doses.

ALEVE (NAPROXEN)

Naproxen is slow to kick in but longer lasting than ibuprofen, making it a good choice for people with mild-to-moderate chronic pain.

Best for: Inflammation, hangover, lasting headache, arthritis

Not great for: Quick pain relief

Watch out for: Like all NSAIDs, naproxen carries some cardiovascular risk and is associated with stomach distress.

THE UPSHOT

Taking too much of any painkiller is bad for you, and not just in the ways we’ve already discussed. People who rely on over-the-counter medication for daily headaches often find that the medication itself can cause additional headaches, called rebound headaches. If you find yourself taking over-the-counter drugs for the same reason every day, it’s time to talk to your doctor about the underlying issue and other treatment options.

Fossilized Fat Shows 550-Million-Year-Old Sea Creature May Have Been the World's First Animal

Ilya Bobrovskiy, the Australian National University
Ilya Bobrovskiy, the Australian National University

A bizarre sea creature whose fossils look like a cross between a leaf and a fingerprint may be Earth's oldest known animal, dating back 558 million years.

As New Scientist reports, researchers from the Australian National University (ANU) made a fortunate find in a remote region of Russia: a Dickinsonia fossil with fat molecules still attached. These odd, oval-shaped creatures were soft-bodied, had rib structures running down their sides, and grew about 4.5 feet long. They were as “strange as life on another planet,” researchers wrote in the abstract of a new paper published in the journal Science.

Another variety of fossil
Ilya Bobrovskiy, the Australian National University

Although Dickinsonia fossils were first discovered in South Australia in 1946, researchers lacked the organic matter needed to classify this creature. "Scientists have been fighting for more than 75 years over what Dickinsonia and other bizarre fossils of the Edicaran biota were: giant single-celled amoeba, lichen, failed experiments of evolution, or the earliest animals on Earth,” senior author Jochen Brocks, an associate professor at ANU, said in a statement.

With the discovery of cholesterol molecules—which are found in almost all animals, but not in other organisms like bacteria and amoebas—scientists can say that Dickinsonia were animals. The creatures swam the seas during the Ediacaran Period, 635 million to 542 million years ago. More complex organisms like mollusks, worms, and sponges didn’t emerge until 20 million years later.

The fossil with fat molecules was found on cliffs near the White Sea in an area of northwest Russia that was so remote that researchers had to take a helicopter to get there. Collecting the samples was a death-defying feat, too.

“I had to hang over the edge of a cliff on ropes and dig out huge blocks of sandstone, throw them down, wash the sandstone, and repeat this process until I found the fossils I was after,” lead author Ilya Bobrovskiy of ANU said. Considering that this find could change our understanding of Earth’s earliest life forms, it seems the risk was worth it.

[h/t New Scientist]

The Weird, Disturbing World of Snail Sex

iStock
iStock

Romance is rare in the animal kingdom. Instead of wooing their partners before copulating, male ducks force themselves onto females, depositing genetic material with spiky, corkscrew penises. Then, there's tardigrade sex, which is less violent but not exactly heartwarming. Females lay eggs into a husk of dead skin. The male then ejaculates onto the eggs while stroking the female, and the whole process can take up to an hour.

But you can't talk about disturbing mating rituals in nature without mentioning snails. If you're unfamiliar with snail sexuality, you may assume that snail sex falls on the vanilla side: The mollusks, after all, are famous for being slow-moving and they don't even have limbs. But if you have the patience to watch a pair of snails going at it, you'll notice that things get interesting.

The first factor that complicates snail sex is their genitalia. Snails are hermaphrodites, meaning individuals have both a male set and female set of parts, and any two snails can reproduce with each other regardless of sex. But in order for a couple of snails to make little snail babies, one of them needs to take on the role of the female. That's where the love dart comes in.

The love dart, technically called a gypsobelum, isn't exactly the Cupid's arrow the name suggests. It's a nail-clipping-sized spike that snails jab into their partners about 30 minutes before the actual sex act takes place. The sliver is packed with hormones that prepare the receiving snail's body for sperm. Depending on the species, only one snail might release the dart, or they both might in an attempt to avoid becoming the female of the pair. You can watch the action in the video below.

For sex to be successful, both snails must insert their penises into the other's vaginal tracts at the same time. Both snails deposit sperm, and the strength of the love dart ultimately determines whether or not that sperm fertilizes their partner's eggs.

That's assuming the snail survives the little love-stab. In human proportions, the love dart is the equivalent of a 15-inch knife. Fortunately, snails are resilient creatures, and gastropod researcher Joris Koene tells KQED he's only ever seen one snail die from the transfer.

Snails also have a way of making it up to their partners after skewering them with a hormone stick. Their sperm deposit contains a dose of fortifying nutrients, something scientists refer to as a nuptial gift. It may not equal the energy expended during sex, but its enough to give them a small post-coital boost.

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