The Brains of Anxious People May Perceive the World Differently

iStock
iStock

A study showed that people with generalized anxiety disorder unconsciously label harmless things as threats, which may serve to further their anxiety. These findings were published in the journal Current Biology.

Psychologists recognize several forms of clinical anxiety. The most common is generalized anxiety disorder, or GAD, in which people frequently feel very worried or anxious even when it seems like there’s nothing to worry about. Some studies have suggested that anxiety disorders may stem from a process called overgeneralization.

In overgeneralization, the brain lumps both safe and unsafe things together and labels them all unsafe. For this reason, the researchers also call this the “better safe than sorry” approach. Our brains naturally pay more attention to negative or threatening information in our environments. If anxious people perceive more threats in the world around them, it would make a lot of sense for them to be worried.

To find out if overgeneralization was involved, researchers recruited 28 people diagnosed with GAD and 16 people without anxiety and brought them into the lab. The experiment had two parts: training and testing. In the training section, study participants learned to differentiate between three different sounds. Each sound was tied to a different outcome; pressing a key could lead to winning money (the “positive” tone), losing money (the “negative” tone), or nothing (the “neutral” tone).

In the second phase of the experiment, researchers played 15 different sounds for the participants and asked them to press a key when they heard a sound they recognized from the training phase. If they guessed right, they’d win money, but if they guessed wrong, the researchers would take some of their money back.

Because of the risk of losing money, the best strategy for everyone would be a conservative one—not pressing the button much at all based on the assumption that most of the tones were new. But anxious participants were trigger-happy, believing they’d heard many of the unfamiliar tones before. The experience of winning and losing money in training had made a strong emotional impression on them, which led them to overgeneralize new information as relevant.

The researchers also administered brain scans during the testing phase. They found notable differences between anxious and non-anxious brains. While they were focused on parsing new information, anxious people showed more activation in several parts of the brain, including the amygdala, a region associated with fear and worry.

"We show that in patients with anxiety, emotional experience induces plasticity in brain circuits that lasts after the experience is over," senior co-author Rony Paz said in a press release. "Such plastic changes occur in primary circuits that later mediate the response to new stimuli, resulting in an inability to discriminate between the originally experienced stimulus and a new similar stimulus. Therefore, anxiety patients respond emotionally to such new stimuli as well, resulting in anxiety even in apparently irrelevant new situations. Importantly, they cannot control this, as it is a perceptual inability to discriminate."

Paz noted that in dangerous circumstances, the hyper-vigilance associated with anxiety might be a good thing. The problem is that most circumstances aren’t dangerous. "Anxiety traits can be completely normal, and even beneficial evolutionarily," he says. "Yet an emotional event, even minor sometimes, can induce brain changes that might lead to full-blown anxiety."

Great White Sharks May Have Led to Megalodons' Extinction

iStock.com/cdascher
iStock.com/cdascher

The megalodon has been extinct for millions of years, but the huge prehistoric shark still fascinates people today. Reaching 50 feet long, it's thought to be the largest shark to ever stalk the ocean, but according to a new study, the predator may have been brought down by familiar creature: the great white shark.

As Smithsonian reports, the analysis, published in the journal PeerJ, finds that the megalodon may have vanished from seas much earlier that previously believed. Past research showed that the last megalodons died roughly 2.6 million years ago, a time when other marine life was dying off in large numbers, possibly due to a supernova blasting Earth with radiation at the end of the Pliocene epoch.

A team of paleontologists and geologists revisited the fossils that this conclusion was originally based on for their new study. They found that many of the megalodon remains had been mislabeled, marked with imprecise dates, or dated using old techniques. After reassessing the specimens, they concluded that the species had likely gone extinct at least 1 million years earlier than past research indicates.

If the megalodon vanished 3.6 million years ago rather than 2.6 million years ago, it wasn't the victim of supernova radiation. One known factor that could explain the loss of the 13 million-year-old apex predator at this time is the rise of a new competitor: the great white shark. This predator came on the scene around the same time as the megalodon's decline, and though a full-grown great white shark is less than half the size of a mature megalodon, the species still would have been a stressor. Adult great whites likely competed with juvenile megalodons, and with the megalodon's favorite prey—small whales—becoming scarce at this time, this may have been enough to wipe the megalodons from existence.

Even if great white sharks eventually beat megalodons for dominance in the oceans, the megalodon's status as one of the most fearsome predators of all time shouldn't be contested. The giant sharks had 7-inch teeth and a bite stronger than that of a T. rex.

[h/t Smithsonian]

From Squatty Potty to Squat-N-Go: The Best Toilet Stool for Every Bathroom

iStock.com/eldemir
iStock.com/eldemir

In 2015, Squatty Potty's bathroom stool plopped into the popular conscience with a viral commercial that featured a unicorn joyfully pooping out a conveyor belt's worth of ice cream. The video racked up more than 35.9 million views on YouTube and reportedly caused a 600 percent jump in sales. "The stool for better stools" was a hit.

Now, it's a hit with the medical community, too. New research out of Ohio State University finds that the toilet stool—which aims to relax the puborectalis muscle and straighten out the rectum, making it easier to poop—really does help people who strain to empty their bowels. The study, published in the Journal of Clinical Gastroenterology's March 2019 issue, only involved 52 people, but it's the first clinical research into the Squatty Potty, and the results were very positive—71 percent of participants said they experienced faster bowel movements after using the stool for a month. A full 90 percent said they experienced less straining than before.

Since the Squatty Potty debuted, the company has inspired plenty of copycats, as well as launching a number of other official Squatty Potty design iterations targeted at every type of user. Here are the best toilet stool options for every bathroom.

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1. If You're Hesitant to Commit: The Squatty Potty Original

At just $25, the original Squatty Potty is a great entry-level option that will allow you to try out the system without sinking a ton of money into it. (And it's a whole lot cheaper than an endless supply of Metamucil.) The white plastic isn't the most elevated decor option, but it's durable, easy to clean, and relatively unobtrusive. It's available in a 7-inch-tall version for standard toilets or a 9-inch-tall version for comfort-height porcelain thrones. If you're not sure how tall your toilet is, the company makes an adjustable height Squatty Potty that can be configured to fit anywhere.

Buy it on Amazon, from Squatty Potty's website for $25, or at these other retailers:

2. If Your Bathroom is Tiny: The Squatty Potty Curve

The original Squatty Potty can be a bit clunky, but a newer version offers all the health benefits without taking up as much space. The Curve has a thinner footprint so that it doesn't stick out quite so far from under your toilet, but still has just enough room for your feet. The 7-inch stool comes in white, pink, black, and gray.

Buy it for $25 on Squatty Potty's website.

3. If You Text on the Toilet: The Keeney Bathroom Stool

A white and blue Keeney toilet stool
Keeney, Amazon

Keeney's toilet stool offers a few unusual features. For one, it has a storage bin designed to keep your wet wipes close at hand. More importantly, it's designed to hold up more than just your feet—it has a smartphone/tablet holder, too. Though toilet stools are designed to make your bowel movements speedier, if you're the kind of person who likes to spend a lot of time on the can, you can also tuck your smartphone into the built-in groove in the stool designed to keep your screen at optimal viewing angles. Whether you're watching Netflix or looking at Tinder, it offers a hands-free option that you're not going to find on any brand-name Squatty Potty. Ergonomically, it's also got slightly angled footrests designed to put you in the optimal pooping position.

Buy it on Amazon for $21.

4. If You're Into Minimalist Design: The Squatty Potty Slim

Great bowel movements and great interior design don't have to be mutually exclusive. Squatty Potty's high-fashion option may be pricier, but it doesn't have the medical-device vibes of the original model, either. Designed for small, urban apartments, it's a bit bigger than the Curve but a lot more aesthetically pleasing. The teak finish is great if you're going for a Scandinavian minimalist vibe, while the acrylic glass Slim Ghost model has an artsy mid-century modern look.

Buy the Slim Teak or the Slim Ghost on Squatty Potty's website for $60 and $80, respectively, or on Amazon for $80 or $83.

5. If You Need to Go on the Go: Squat-N-Go Bamboo X Toilet Stool

While Squatty Potty does make a portable version of its bathroom stool (the cleverly named Porta-Squatty), the most convenient travel stool is made by a competitor. Squat-N-Go's foldable footstool comes in two different pieces for easy storage and portability. The two bamboo platforms essentially act as stilts, propping up your feet separately. They offer the most customizable fit, with 7-inch, 8-inch, and 9-inch heights and the ability to place each footstool anywhere around the toilet, at any angle. When you're done, they fold down to just an inch tall and can be stowed in the included travel bag.

Buy it on Amazon for $40 or at these other retailers:

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