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Joan Marcus

20 Things You Might Not Have Known About Hamilton

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Joan Marcus

No one could have predicted that a hip-hop-infused musical based on the life of Alexander Hamilton would be Broadway’s hottest ticket, but Hamilton—which Lin-Manuel Miranda wrote over the course of six years—is sold out through next year. Here are a few things you might not have known about Miranda’s take on the life and times of the first Secretary of the Treasury.

1. IT WAS INSPIRED BY RON CHERNOW’S BIOGRAPHY OF HAMILTON.

Not long after his show In the Heights won four Tony Awards in 2008, Lin-Manuel Miranda went on vacation. Before he left, he picked up a biography called Alexander Hamilton. “I was just browsing the biography section. It could have been Truman,” he told 60 Minutes. “I got to the part where a hurricane destroys St. Croix, where Hamilton is living. And he writes a poem about the carnage and this poem gets him off the island.”

“That is part and parcel with the hip-hop narrative: writing your way out of your circumstances, writing the future you want to see for yourself,” Miranda told The New York Times. “This is a guy who wrote at 14, ‘I wish there was a war.’ It doesn’t get more hip-hop than that.”

Miranda recalled to Vogue that “I Googled ‘Alexander Hamilton hip-hop musical’ and totally expected to see that someone had already written it. But no. So I got to work.”

2. IT TOOK MIRANDA A YEAR TO WRITE THE FIRST SONG—AND ANOTHER YEAR TO WRITE THE SECOND SONG.

He performed the song, “Alexander Hamilton,” at the White House in 2009 (you can watch the video above). “From what I hear,” Questlove, who produced the cast album, told Billboard, “the president won't cease to let you know that: ‘The White House is where it began.’”

It took Miranda another year to craft Hamilton’s anthem, “My Shot.” “Every couplet needed to be the best couplet I ever wrote,” Miranda told 60 Minutes. “That’s how seriously I was taking it.”

When he needed to come up with lyrics, he told Smithsonian, he walked. “For Hamilton what I’d do is write at the piano until I had something I liked,” he said. “I’d make a loop of it and put it in my headphones and then walk around until I had the lyrics. That’s where the notebooks come in, sort of write what comes to me, bring it back to the piano. I kind of need to be ambulatory to write lyrics.”

3. IT STARTED AS A MIXTAPE, NOT A MUSICAL.

Initially, Miranda said he was working on a concept album inspired by the life of Alexander Hamilton called The Hamilton Mixtape. “I always had an eye toward the stage for the story of Hamilton's life, but I began with the idea of a concept album, the way Andrew Lloyd Webber's Evita and Jesus Christ Superstar were albums before they were musicals,” Miranda recounted to the Hollywood Reporter. “And I built this score by dream casting my favorite artists. I always imagined George Washington as a mix between Common and John Legend (a pretty good description of Christopher Jackson, actually, who plays our first president); Hercules Mulligan was Busta Rhymes; and Hamilton was modeled after my favorite polysyllabic rhyming heroes, Rakim, Big Pun, and Eminem.”

The reason, he told The New York Times, was because “I wanted to be a little more selfish with this—I wanted the lyrics to have the density that my favorite hip-hop albums have … It was easier to think of it as a hip-hop album, because then I could really just pack the lyrics. [But] I only know how to write musicals.” He performed 12 musical numbers from The Hamilton Mixtape at Lincoln Center’s American Songbook series in January 2012; he began workshopping the show in 2014. It played The Public beginning in January 2015 and made the jump to Broadway in July 2015 (it officially opened in August).

4. MIRANDA DID HIS RESEARCH—BOTH HISTORICALLY AND MUSICALLY.

In addition to reading Chernow’s biography of Hamilton, Miranda read Hamilton’s letters and works and visited sites important to the American Revolution in New York City. He explained to The Atlantic that, to understand Burr, he read The Heartbreak of Aaron Burr by H.W. Brands, and to nail the dueling code of the day, he picked up Affairs of Honor by Joanne Freeman. He wrote, for a time, at the Morris-Jumel Mansion, which Washington once used as a headquarters during the Revolutionary War. In October 2014, before the show began playing at The Public, he and director Thomas Kail went to the Weehawken, New Jersey dueling ground where Burr shot Hamilton (the actual dueling grounds are covered by train tracks now, but there is a small memorial there).

Miranda also looked at other musicals before diving into Hamilton, like Jesus Christ Superstar and Les Miserables. “I really got my Les Miz on in this score, like being really smart about where to reintroduce a theme,” he told The New Yorker. “In terms of how it accesses your tear ducts, nothing does it better than that show.”

5. CHERNOW BECAME A HISTORICAL CONSULTANT FOR THE SHOW.

Miranda met Chernow before he performed the song that would become “Alexander Hamilton” at the White House (in fact, he sang the song to Chernow in the biographer’s living room), and soon Chernow became a consultant on the show. “[Miranda] was smart enough to know that the best way to dramatize this story was to stick as close to the facts as possible,” Chernow told 60 Minutes.

“I’m theater people, and theater people, the only history they know is the history they know from other plays and musicals,” Miranda told The Atlantic. “So to that end, I felt an enormous responsibility to be as historically accurate as possible, while still telling the most dramatic story possible. And that’s why Ron Chernow is a historical consultant on the thing, and, you know, he was always sort of keeping us honest. And when I did part from the historical record or take dramatic license, I made sure I was able to defend it to Ron, because I knew that I was going to have to defend it in the real world. None of those choices are made lightly.”

According to Smithsonian, Chernow looked at every draft and every song and assessed everything for accuracy.

6. THE SHOW WASN’T ALWAYS SUNG THROUGH.

Hamilton is sung and rapped from start to finish, but it wasn’t always that way. “We actually went down the road with a playwright,” Miranda told Grantland. “There’s a version of Act 1 where we had songs and they were the songs that are in the show, but we found that if you start with our opening number, you can’t go back to speech. The ball is just thrown too high in the air.”

The show features one scene that isn’t sung, and which Miranda kept off of the cast album: In “Tomorrow There’ll Be More of Us,” which takes place between “Dear Theodosia” and “Non-Stop,” Hamilton finds out that his friend Laurens has been killed. “I made a decision not to record this scene on the album, for two reasons,” Miranda wrote on Tumblr:

1) It really is more of a scene than a song, the only SCENE in our show, and I think its impact is at its fullest in production form. 2) As someone who grew up ONLY listening to cast albums (we ain’t have money for a lot of Broadway shows, like most people) those withheld moments were REVELATIONS to me when I finally experienced them onstage, years later. Hamilton is sung through, and I wanted to have at least ONE revelation in store for you. I stand by the decision, and I think the album is better for it.

7. HE WROTE KING GEORGE’S SONG ON HIS HONEYMOON.

Because he’s an interloper on the proceedings of Hamilton, King George’s song, You'll Be Back, is quite different from the rest of the show’s numbers. “It’s a throwback to a sixties Beatles tune,” Jonathan Groff, who plays King George, told Vogue. “And it’s a breakup song between America and England, which is fabulous. He’s like, ‘You’re leaving me? Oh, really? Well, good luck with that.’” Miranda wrote the song while on his honeymoon in 2010 “without a piano around,” he told Grantland.

8. THE ORIGINAL VERSION OF “MY SHOT” HAD AN EXTRA VERSE FOR HERCULES MULLIGAN.

“I’m Hercules Mulligan, a tailor spying on the British Government / I take the measurements, information and then I smuggle it / Up to my brother's revolutionary covenant / I’m running with the Sons of Liberty, and I’m loving it,” Mulligan raps. At that point, neither the Marquis de Lafayette nor John Laurens were part of the song. You can hear the rest of the demo here; portions of Mulligan’s verse ended up in “Yorktown (World Turned Upside Down).”

9. MIRANDA WROTE “WAIT FOR IT” ON THE SUBWAY.

“I was going to a friend’s birthday party in [Brooklyn],” he said, when a lyric from the chorus to Aaron Burr’s song, “Wait for It,” came to him.  “I sang the melody into the iPhone, then I went to the guy’s party for 15 minutes, and wrote the rest of the song on the train back home.”

10. THE RAP IN “GUNS AND SHIPS” IS FAST. REALLY, REALLY FAST.

“I believe that form [rap] is uniquely suited to tell Hamilton’s story, because it has more words per measure than any other musical genre,” Miranda told 60 Minutes. “It has rhythm, and it has density, and if Hamilton had anything in his writing, it was this density.” The use of rap helps Miranda pack more than 20,000 words into two and a half hours—roughly 144 words per minute, according to Leah Libresco at FiveThirtyEight. “If Hamilton were sung at the pace of the other Broadway shows I looked at, it would take four to six hours,” Libresco wrote. She found that the musical’s fastest paced verse, from the song “Guns and Ships,” clocked in at 6.3 words per second.

11. THE SONGS SAMPLE RAP MUSIC AND REFERENCE RAP SONGS—AS WELL AS OTHER MUSICALS.

As a show that has its roots in rap, it’s not surprising that Miranda has peppered Hamilton with rap references and samples: “My Shot” has elements of Mobb Deep’s “Shook Ones Part II” and an homage to Notorious B.I.G.’s “Going Back to Cali”; the song “Ten Duel Commandments” samples B.I.G.’s “Ten Crack Commandments”; the opening to “Cabinet Battle #1” references Jay-Z’s “Izzo (H.O.V.A.)” and contains parts of “The Message” by Grandmaster Flash; “Meet Me Inside” contains elements of DMX’s “Party Up in Here (Up in Here)”; and “Cabinet Battle #2” references B.I.G’s “Juicy (It’s All Good).” These themes—and samples—show up in other songs throughout Hamilton.

Miranda pays homage to good old fashioned Broadway shows, too: He snatched a line from South Pacific for Burr (“I’m with you but the situation is fraught / You’ve got to be carefully taught,” in “My Shot”), makes reference to the song "Modern Major General" from Pirates of Penzance (when Washington sings, “The model of a modern major general / the venerated Virginian veteran whose men are all / Lining up, to put me on a pedestal,” in “Right Hand Man”), and put parts of “Nobody Needs to Know” from The Last Five Years in “Say No to This.”

Miranda’s lyrics are also packed with historical references. We decoded a few here, and many are annotating the lyrics on Genius (Miranda has also weighed in there). Miranda is working on his own book of annotated lyrics, which will hit stores in April. “I am writing a new set of annotations for the book,” he tweeted. “Not what you'd find on Genius, just things in my brain & heart.”  

12. AT FIRST, MIRANDA COULDN’T DECIDE IF HE WANTED TO PLAY HAMILTON OR BURR.

“I feel an equal affinity with Burr,” he told The New Yorker. “Burr is every bit as smart as Hamilton, and every bit as gifted, and he comes from the same amount of loss as Hamilton. But because of the way they are wired Burr hangs back where Hamilton charges forward. I feel like I have been Burr in my life as many times as I have been Hamilton.” But eventually, he chose Hamilton: “When I get called in for stuff for Hollywood, I get to be the best friend of the Caucasian lead. If I want to play the main guy, I have found, I have to write it ...  [As Hamilton], I get to be cockier than I really am; I get to be smarter than I really am; I get to be more impulsive than I really am—it’s taking the reins off your id for two and a half hours.”

Burr is now played by Leslie Odom Jr. “I stupidly gave him a lot of the best songs,” Miranda told Grantland. “‘Wait for It’ and ‘The Room Where It Happens’ are two of the best songs I’ve ever written in my life and he got them both.”

13. THE CASTING CHOICES WERE DELIBERATE.

“Our goal was: This is a story about America then, told by America now, and we want to eliminate any distance—our story should look the way our country looks,” Miranda told The New York Times. “Then we found the best people to embody these parts. I think it’s a very powerful statement without having to be a statement.” The only main character played by a white actor is King George.

“When I think about what it would mean to me as a 13-, 14-year-old kid, to get this album or see this show—it can make me very emotional,” Odom told The New York Times.

14. MIRANDA CUT GEORGE WASHINGTON’S DEATH FROM THE SHOW.

Initially, Washington’s death was in the show—but Miranda cut it. “Oof. I wrote that. Brutal,” he tweeted:

One cut line...

BURR: And in our grief-
HAMILTON/JEFFERSON: He unites us one last time.

“It was a cut musical moment, & actually began with Burr singing, ‘I hear wailing in the streets…,’” he continued. He cut it, he said, “because we sing a whole song about him saying goodbye and even though the moment gave us feels, it was redundant.”

15. THE LOTTERY FOR TICKETS SOMETIMES FEATURES ITS OWN SHOW.

So far, #Ham4Ham—as the show is called—has regularly featured members of Hamilton’s cast as well as other Broadway performers; it takes place on the street outside the Richard Rodgers theater. Among other things, Miranda has dueted with Broadway star Lea Salonga; answered audience questions with just Les Miz lyrics; showed his love for the show’s tech people by running the entire cast through a number while the cues were called; presided over the three actors who have played King George lip syncing a song from the show; and hosted a contest to see which Hamilton fan could nail the Lafayette rap in “Guns and Ships.” Miranda puts on the show, he told Rolling Stone, because he knows that most of the hundreds of people who line up for the lottery won’t win, and he doesn’t want them to walk away with nothing.

16. WHEN CELEBRITIES COME BACKSTAGE, THEY SIGN A LIFE-SIZED CUTOUT OF HAMILTON.

Jennifer Lopez, Danny DeVito, Steven Spielberg, Sting, Jon Lasseter, Oprah, Vice President Joe Biden, and more have put their kind words—and their John Hancocks—on and around Hamilton.

17. THE STARS OF THE SHOW HELPED TO RAISE MONEY FOR THE ORPHANAGE ELIZA HAMILTON STARTED.

In 1806, Eliza Hamilton was one of the founders of New York City’s first private orphanage; these days, it’s called Graham Windham. Miranda and Philippa Soo, who plays Eliza in Hamilton, performed at an event to raise money for the organization. “What a time at the @GrahamWindham luncheon today,” he tweeted. “When the kids (from ELIZA'S ORGANIZATION) sang ‘Eliza, you have done enough.’ I mean…”

18. THE PRESIDENT IS A HUGE FAN.

President Obama called the show “brilliant,” adding, “so much so that I’m pretty sure this is the only thing that Dick Cheney and I have agreed on—during my entire political career.”

19. IT HAS STEPHEN SONDHEIM'S SEAL OF APPROVAL.

At some point, Miranda showed his songs to Steven Sondheim, the man behind Into the Woods, Sweeney Todd, and many more musicals, who told The New York Times, “He sent me lyrics printed out, and recordings of the songs. This raised obvious red flags: I worried that an evening of rap might get monotonous; I thought the rhythm might become relentless. But the wonderful thing about Lin-Manuel’s use of rap is that he’s got one foot in the past. He knows theater … Hamilton is a breakthrough … We’ll certainly see more rap musicals. The next thing we’ll get is Lincoln set to rap. If you think I’m kidding, talk to me in a year.”

20. THERE’S GOING TO BE AN ACTUAL MIXTAPE.

Though Hamilton evolved beyond Miranda’s original vision, there are now plans to make a mixtape for real: “So the show is done. Cast album is out. Now we begin planning The Hamilton Mixtape. Remixes & Covers & Inspired bys. FOR REAL. GET READY,” he tweeted in October. “I was originally trying to get the mixtape done with Atlantic before we opened, but that's like performing surgery while having a baby.” The mixtape will feature a third, unreleased rap battle, “where Ham, Mad & Jeff go IN on slavery,” Miranda tweeted. “It was sort of our homage to ‘Hail Mary’ [by Tupac Shakur],” he told Billboard. Hopefully, it will also feature this cut rap about John Adams (who once called Hamilton the "bastard brat of a Scot peddler"). There’s no firm date, but the mixtape is expected early next year.

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5 Killer Pieces of Rock History Up for Auction Now (Including Prince’s Guitar)
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Karrah Kobus/NPG Records via Getty Images

If you’ve ever wanted to own a piece of rock history, now is the time. A whole host of cool music memorabilia from the 20th century is going up for sale through Julien’s Auctions in Los Angeles as part of its “Icons and Idols” sale. If you’ve got the dough, you can nab everything from leather chairs from Graceland to a shirt worn by Jimi Hendrix to never-before-available prints that Joni Mitchell signed and gave to her friends. Here are five highlights from the auction:

1. ELVIS’S NUNCHUCKS

Elvis’s nunchucks
Courtesy Julien's Auctions

Elvis’s karate skills sometimes get a bad rap, but the King earned his first black belt in 1960, and went on to become a seventh-degree black belt before opening his own studio in 1974. You can cherish a piece of his martial arts legacy in the form of his nunchaku. One was broken during his training, but the other is still in ready-to-use shape. (But please don’t use it.) It seems Elvis wasn’t super convinced of his own karate skills, though, because he also supposedly carried a police baton (which you can also buy) for his personal protection.

2. PRINCE’S GUITAR

A blue guitar used by Prince
Courtesy Julien's Auctions

Prince’s blue Cloud guitar, estimated to be worth between $60,000 and $80,000, appeared on stage with him in the late ’80s and early ’90s. The custom guitar was made just for Prince by Cloud’s luthier (as in, guitar maker) Andy Beech. The artist first sold it at a 1994 auction to benefit relief efforts for the L.A. area’s devastating Northridge earthquake.

3. KURT COBAIN’S CHEERLEADER OUTFIT

Kurt Cobain wearing a cheerleader outfit in the pages of Rolling Stone
Courtesy Julien's Auctions

The Nirvana frontman wore the bright-yellow cheerleader’s uniform from his alma mater, J.M. Weatherwax High School in Aberdeen, Washington, during a photo shoot for a January 1994 issue of Rolling Stone, released just a few months before his death.

4. MICHAEL JACKSON’S WHITE GLOVE

A white glove covered in rhinestones
Courtesy Julien's Auctions

A young Michael Jackson wore this bejeweled right-hand glove on his 1981 Triumph Tour, one of the first of many single gloves he would don over the course of his career. Unlike later incarnations, this one isn’t a custom-made glove with hand-sewn crystals, but a regular glove topped with a layer of rhinestones cut into the shape of the glove and sewn on top.

The auction house is also selling a pair of jeans the star wore to his 2003 birthday party, as well as other clothes he wore for music videos and performances.

5. WOOD FROM ABBEY ROAD STUDIOS

A piece of wood in a frame under a picture of The Beatles
Courtesy Julien's Auctions

You can’t walk the halls of Abbey Road Studios, but you can pretend. First sold in 1986, the piece of wood in this frame reportedly came from Studio Two, a recording space that hosted not only The Beatles (pictured), but Pink Floyd, Stevie Wonder, Eric Clapton, and others.

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5 Dubious Historical Antidotes for Poison (and What Actually Works)
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An artificial bezoar stone from Goa, India
Wellcome Images // CC BY 4.0

When it comes to their health, humans will believe just about anything. In this extract from the new book Quackery: A Brief History of the Worst Ways to Cure Everything, authors Lydia Kang, MD, and Nate Pedersen discuss some of the more questionable ways people once tried to protect themselves from poison—whether or not the methods actually worked.

Poison is everywhere. Naturally or unnaturally, it can be in the soil (arsenic), in the air (carbon monoxide), in your drinks (lead), and in your food (cyanide). With so much danger around, it’s no wonder humans have obsessed over finding a universal antidote—the one thing that could save us from all toxins. Imagine you’re a medieval prince about to inherit the throne. Chances are, there are a lot of power-hungry wannabes waiting in the wings. A little arsenic or hemlock might be your best friend or your worst nightmare. Just in case, best have an antidote on standby.

For millennia, a certain amount of magical thinking was employed when arming oneself against poison because science was inconveniently slow to catch up. So grab your handy unicorn horn and a bezoar, and let’s take a look.

1. BEZOARS

Bezoars have been used for centuries as antidotes to poisons. A bezoar is solid mass of undigested food, plant fibers, or hair found in the digestive tracts of animals, including deer, porcupines, fish, and, yes, humans. Anyone with a cat is familiar with the less-cool feline version: hairballs.

Bezoars and other stone-like items created by animals often had a good story behind them. Legends told of deer that would eat poisonous snakes and become immune or cry tears that solidified into poison-curing stones. First-century Arabic author al-Birumi claimed bezoars could protect against one poison called “the snot of Satan,” which we hope never ever to encounter. By the 12th century, when Europe became plagued with, uh, plagues, the bezoar crept into pharmacopeias as panaceas and alexipharmics (poison antidotes).

Bezoars were a seductive notion for the rich and royal, who were at risk of assassination. The stones were often enclosed in bejeweled gold for display or worn as amulets. Indian bezoars, in particular, were sought for life-threatening fevers, poisonous bites, bleeding, jaundice, and melancholy. Consumers were also known to scrape off a bit of bezoar and add it to their drinks for heart health and kidney stones. These tonics were sometimes adulterated with toxic mercury or antimony, which caused vomiting and diarrhea, making buyers think they were effective.

But were they? One team of researchers soaked bezoars in an arsenic-laced solution and found that the stones absorbed the arsenic or that the poison was neutralized. Hard to say if it worked well enough to cure a fatal dose. Ambroise Paré, one of the preeminent French physicians of the 16th century, was also a doubter. The king’s cook, who’d been stealing silver, was given the choice between hanging or being Paré’s lab rat. He chose the latter. After the cook consumed poison, Paré looked on as a bezoar was stuffed down his throat. Six hours later, he died wracked with pain. Perhaps he chose ... poorly?

2. MITHRIDATES

This antidote was named after Mithridates VI, the king of Pontus and Armenia Minor. Born in 134 BCE, he pretty much invented the phrase “what doesn’t kill you makes you stronger” by consuming poisons daily to prevent his own assassination. His royal home was stocked with stingray spines, toxic mushrooms, scorpions, mineral poisons, and a poisonous plant–filled garden. He was so unpoisonable that after his son took over his kingdom and he faced execution, he couldn’t even commit suicide by poison! He begged a guard to stab him to death. (It worked.)

Though the king’s actual recipe for the antidote is nowhere to be found, versions began to circulate after his death, and they became synonymous with the king himself. Compounds with lengthy and expensive ingredient lists prevailed, including iris, cardamom, anise, frankincense, myrrh, ginger, and saffron. In the first century, Pliny the Elder snarkily remarked, “The Mithridatic antidote is composed of fifty-four ingredients ... Which of the gods, in the name of Truth, fixed these absurd proportions? ... It is plainly a showy parade of the art, and a colossal boast of science.”

Showy or not, people would take the extensive mix of herbs, pound them together with honey, and eat a nut-sized portion to cure themselves. At least it endowed them with expensive-smelling breath.

3. HORNS

An apothecary shop sign in the shape of a unicorn
An ivory pharmacy sign in the shape of a unicorn's head
Wellcome Images // CC BY 4.0

Unicorn horns have been considered a part of antidote legend since the mythical beast galloped into literature around 300 BCE. For centuries afterward, real earthly beasts would sacrifice their lives and their horns to slake our thirst for the miraculous, nonexistent animal, including rhinoceroses, narwhals, and oryx. Even fossilized ammonites were used. It was believed that drinking vessels made of such horns might neutralize poisons, and wounds could be cured by holding them close by. In the 16th century, Mary, Queen of Scots reportedly used a unicorn horn to protect her from poisoning. Too bad it didn’t prevent her beheading.

4. PEARLS

Pearls have long been thought to be powerful antidotes. A beautiful, rare gem created by the homely oyster, a pearl is born out of annoyance (the mollusk secretes iridescent nacre to cover an irritant, like a parasite or grain of sand). Pretty as they are, they’re about as useful as the chalky antacid tablets on your bedside table; both are chiefly made of calcium carbonate. Good for a stomachache after some spicy food, but not exactly miraculous.

Pearl powder has been used in traditional Chinese medicine to treat a variety of diseases, and Ayurvedic physicians used it as an antidote in the Middle Ages. It was also reported to make people immortal. An old Taoist recipe recommended taking a long pearl and soaking it in malt, “serpent’s gall,” honeycomb, and pumice stone. When softened, it would be pulled like taffy and cut into bite-sized pieces to eat, and voilà! You would suddenly no longer need food to stay alive. Cleopatra famously drank down a large and costly pearl dissolved in wine vinegar, though in that case she wasn’t avoiding poison. She didn’t want to lose a bet with Antony—which might have fatally injured her pride.

5. THERIAC

Albarello vase for theriac, Italy, 1641
A vase for theriac, Italy, 1641
Wellcome Images // CC BY 4.0

Theriac was an herbal concoction created in the first century by Emperor Nero’s physician, Andromachus, who was reported to have Mithridates’s secret notes. It was a mashed formula of about 70 ingredients, including cinnamon, opium, rose, iris, lavender, and acacia in a honey base. In the 12th century, theriac made in Venice was branded as particularly special, and Venetian treacle (derived from a Middle English translation of theriac) became a hot commodity. Its public, dramatic production often attracted curious crowds.

By the 18th century, cheaper golden syrup was substituted for honey. As treacle began to lose its luster as a treatment, its definition as an herbal remedy disappeared from common vernacular. But the sweet syrup remained. Which is why when we think of treacle, we think of treacle tarts, not a fancy means of saving ourselves from a deathly poisoning.

BONUS: WHAT ACTUALLY WORKS

Thankfully, science has brought us a wide range of antidotes for many items we shouldn’t be exposed to in dangerous quantities, if at all. N-acetylcysteine, fondly referred to as NAC by doctors, saves us from acetaminophen overdoses. Ethanol can treat antifreeze poisoning. Atropine, ironically one of the main components of plants in the toxic nightshade family (such as mandrake), can treat poisoning from some dangerous fertilizers and chemical nerve agents used as weapons. For years, poisonings were treated with emetics, though it turns out that plain old carbon—in the form of activated charcoal—can adsorb poisons (the poisons stick to the surface of the charcoal) in the digestive system before they’re dissolved and digested by the body.

As long as the natural world and its humans keep making things to kill us off, we’ll keep developing methods to not die untimely deaths.

We’ll just leave the fancy hairballs off the list.

The cover of the book Quackery: A Brief History of the Worst Ways to Cure Everything
Workman Publishing

Excerpt from Quackery: A Brief History of the Worst Ways to Cure Everything by Lydia Kang, MD and Nate Pedersen/Workman Publishing. Used with permission.

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