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Answering Some Burning, Headache-Inducing Questions About Hangovers

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If you’ve never experienced a hangover, the rest of us are jealous. In a nutshell, a hangover is your body’s physical reaction to drinking too much alcohol.

For some people, it takes the form of a vicious headache. For others, it might cause fatigue, nausea, trembling, anxiety, or all of the above. From both science and experience, we know that it’s worse if you drink after skipping a meal or not sleeping. You can also exacerbate your hangover if you drink while dancing. In short, hangovers are no fun at all.

In case you’ve ever wanted to quantify the severity of your hangover, you’re in luck. About five years ago, researchers at the NIH developed a scale for studying hangovers (check out the link—there's math) and later validated their findings. Up to that point, very little scientific research had been done on hangovers, and they wanted to provide metrics by which individuals’ experiences could be studied.

Myth-ing the Point

Alcohol affects every person differently. How you digest it is based on your gender, weight, and genetics. The prevailing theory on the subject is that hangovers are much the same. But since everyone exhibits different symptoms the morning after, a host of myths have popped up around its causes.

One of the most common complaints is that hangovers are caused by drinking multiple types of alcohol. Your blood alcohol content (BAC) works the same no matter the type of alcohol in your glass, so the severity of your hangover isn’t determined by this factor. Like the effect of different types of booze on your mood, it’s psychological rather than physical fact.

Some science-savvy boozehounds have blamed congeners—compounds other than alcohol produced during distilling—for their aching heads. Found most commonly in whiskey, at least one study has found that there’s almost no difference between whiskey and vodka on physical intoxication.

Another myth is that it’s caused by changes in your blood sugar. Though alcohol does make your blood sugar spike, it’s probably normalized by the time you wake up to regret your nightcap.

Dehydration is often blamed as the cause of a hangover. Veteran drinkers will often advise others to alternate water with their boozy beverage of choice to avoid discomfort the next day. Dehydration is terrible, but it alone is unlikely to cause a hangover. (If you've ever rehydrated during a nasty hangover, you might have noticed that the symptoms stayed the same.)

Alcohol signals the pituitary gland to stop producing vasopressin, a chemical that keeps your body lubricated. Shutting down its production funnels all the liquid coming into your body directly to your bladder. This diversion also means that your organs aren’t getting enough fluid, so they steal water from your brain, which might just be the cause of your brain-rattling headache.

Many people exhibit almost flu-like inflammatory symptoms with particularly nasty hangovers. Science backs it up: the chemical markers found in the bloodstream during a hangover are very similar to those found in someone having a response to an inflammation. An anti-inflammatory may be the simple fix worth trying.

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What's the Right Way to Make a Sazerac?
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If you pronounce New Orleans "New Or-leens," or if you can’t get enough of those Big Ass Beers sold on Bourbon Street, you’re probably not actually from New Orleans. But if you’re feeling adventurous and missing the Big Easy, a Sazerac might be just what the doctor ordered. 

‘Tails and Stories

A few hundred years ago, you might have actually gotten a doctor’s order for a Sazerac. One of the drink's origin stories claims that it was invented by New Orleans apothecary Antoine Amedie Peychaud. According to this tale, Mr. Peychaud mixed up the drink with his eponymous bitters and served it in an egg coupe in his shop. 

A more likely origin story states that the drink was invented by a different New Orleans resident (though in the same neighborhood). Around 1850, Sewell T. Taylor sold his bar to Aaron Bird and went into the import business. One of his products happened to be Sazerac-de-Forge et Fils brandy. While Taylor was importing, Bird renamed his bar the Sazerac House and began serving a house cocktail that featured Taylor’s brandy and, as the story goes, bitters made by his neighborhood apothecary, Mr. Peychaud.

In the 1870s and 1880s, Europe's grape crops were decimated by an infestation of American aphids. In just four years, French wine production was cut by 67 percent, and even the most dedicated cognac drinkers switched to whiskey. For New Orleans, that meant switching to rye whiskey that was shipped to the city down the Ohio River and through the Mississippi. Thomas Handy, who owned the Sazerac Bar during that time period, likely switched the drink's main ingredient. This take on the signature cocktail is the one that found its way into the 1908 edition of The World's Drinks and How To Mix Them, with the recipe calling for "good whiskey," not Sazerac cognac. 

The origins of the Sazerac’s name is vague. It’s possible that it was a nod to the fact that it was the bar's house cocktail, but it’s also possible that it’s a reference to the brand of brandy. In those days, “cocktail” referred to a specific alcoholic drink format. As put forth by The Balance and Columbian Repository in 1806, a “cock-tail” is “a stimulating liquor composed of spirits of any kind, sugar, water, and bitters.” If you wanted this type of drink with whiskey in it, you would ask for a Whiskey Cocktail. If you wanted Sazerac brandy (until the aphid plague, at least), you'd ask for a Sazerac cocktail.

Hit the Lab

Sazerac Recipe:

2 dashes Peychaud's bitters
.25 oz simple syrup (or a sugar cube)
2 oz good rye whiskey (use the good stuff)
lemon peel for garnish

Place the sugar cube into an absinthe-rinsed rocks glass. Dash the bitters onto the cube and muddle. Add whiskey and one large ice cube and stir to combine. Garnish with a lemon twist.

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What’s the Right Way to Make a Caipirinha?
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The Rio Olympics start in just a few weeks, and all eyes are on Brazil. To celebrate, we decided to focus on the country’s most famous cocktail creation: the Caipirinha.

In form, the Caipirinha is pretty much a Brazilian Daiquiri. It’s made from sugar, lime, and cachaça. Cachaça could be considered a cousin to rum, but it is altogether unique. While most rum is made from molasses, cachaça is made from fresh sugarcane juice.

Unlike rum, which can be made anywhere, cachaça can only be made in Brazil. Though it’s often sold unaged, it is usually matured in woods that are native to Brazil, like peanut and balm. As with wine, beer, and whiskey, different kinds of wood affect the product inside differently.

The classifications of cachaça aren’t based on the type of cask in which it’s aged. It can get a bit confusing: Spirit that is not stored in wood or is kept in stainless steel vats before it’s bottled is often called branca (white). But cachaça aged in wood that doesn’t color the liquor may also be labeled as branca. This category goes under several other names, including prata (silver) and clássica (classic).

Cachaça that’s stored or aged in wood is usually labeled as amarela (yellow), in reference to its color. These may also be labeled as ouro (gold). Envelhecida (aged) cachaça, a subtype of amarela, is a bit more involved: it’s considered aged if more than 50 percent of the content of the bottle has been aged for at least a year in a barrel that’s 700 liters or smaller.

Cachaça is the “third most produced distilled drink in the world,” according to Alcohol In Latin America: A Social and Cultural History. Though more than 5000 brands existed in 2008, it was relatively ignored outside of Brazil until the recent resurgence of craft cocktails. In fact, until 2013, it had to be labeled “Brazilian rum” to be imported into the U.S. As a result, it’s often mistaken by many people for being a type of rum.

Unfortunately, we don’t really know anything definite about the origins of the Caipirinha. Like the Mojito and the Old Fashioned, the formula was perhaps first used in folk medicine. Carlos Lima, the executive director of IBRAC (the Brazilian Institute of Cachaça) told Casa e Jardim that a mix of lime, garlic, and honey with a pour of cachaça was probably used in São Paulo around 1918 as a remedy for the Spanish Flu.

As the story goes, someone eventually decided to skip the garlic and honey. Then, to balance the acidity of the lime, sugar was added. Over time, the drink spread into bars, ice entered the equation, and it became the Caipirinha we know today.

HIT THE LAB

Like the Mojito, the classic Caipirinha recipe is quite simple, but it’s also been the subject of many, many variations. We’ve included the International Bartenders Association (IBA) recipe as well as a modern take on the drink.

Caipirinha
Modified from the IBA website.

2 ounces Cachaça
1/2 of a lime
1 tablespoon sugar

Muddle lime and sugar in an Old Fashioned glass. Fill with ice and pour cachaça over it. Stir and enjoy.

Prata B. (Puerto Rico Asta Ah Brazil)
Recipe by Luis Ramos, bar manager of Bourbon and Branch in San Francisco.

1 3/4 ounces Avua Prata Cachaça
3/4 ounce lime juice
3/4 ounce pineapple gomme syrup
1/2 ounce Pedro Ximenez sherry
1/4 ounce Punt e Mes
Grated nutmeg, lime zest, lime wheel for garnish

Combine all ingredients in a Collins glass. Add crushed ice and stir until glass frosts. Top glass with grated nutmeg, lime zest, and lime wheel.

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