Our Skin Is Covered With Invisible Stripes

Envy the tiger and the zebra no longer. You have stripes of your own.

Human skin is overlaid with what dermatologists call Blaschko’s Lines, a pattern of stripes covering the body from head to toe. The stripes run up and down your arms and legs and hug your torso. They wrap around the back of your head like a speed skater’s aerodynamic hood and across your face. Or they would, if you could see them.

In the early 1900s, German dermatologist Alfred Blaschko reported that many of his patients’ rashes and moles seemed to follow similar formations, almost as though they were tracing invisible lines. But those lines didn’t follow nerves or blood vessels. They didn’t represent any known body system.

Here is how Blaschko depicted these lines in an early paper:

Wikimedia Commons // Public Domain

It turns out these lines are far more extensive than even Blaschko thought—closer to this:

Davide Brunelli, Med Art


And today we know what they are: cellular relics of our development from a single cell to a fully formed human. Each one of us started out as a single cell, and then a little glob of cells. As the cells divided, they differentiated. Some became muscles, others bones, still others organs. And some became skin. As those skin cells continued dividing, they expanded and stretched to cover a quickly growing body. One cell line pushed and swirled through another like steamed milk poured into an espresso to make a latte.

Blaschko’s lines are the molecular evidence of those swirls.

Most people will never see their own stripes. As Dr. Blaschko noted, there are dozens of skin conditions that follow these lines, but most of them affect patches of skin or a single body part, not the entire body. Lined and whorled nevoid hypermelanosis can create beautiful patterns.

And then there are the chimeras. Remember the single cell that turned into a glob? From time to time, two of these starter cells will merge and become a glob together. The glob eventually resolves into a chimera: an animal with two lines of DNA. As the animal’s skin develops, the two groups of cells divide and swirl just like non-chimera skin cells. The difference is that the two groups of chimerical cells are slightly different from each other. Behold the chimera cat Venus:

Sometimes, this difference is obvious. More often in humans, though, it’s too subtle to notice with the naked eye, and can only be spotted under UV light.

8 Surprising Facts About Your Nose

iStock/AntonioGuillem
iStock/AntonioGuillem

Your nose is more than just a bump on your face—it’s an important part of the respiratory system and affects many other senses, including your taste and hearing. For being something that’s so central to our daily interactions with the world, there’s still a surprising amount to discover about the nose. Here's a bit of what we do know.

1. Your nose can detect billions of different odors.

Although the human nose is weak compared to canine sniffers, our noses can detect 1 trillion smells. Strangely, scientists still aren’t sure exactly how we smell. For decades, researchers thought the olfactory system worked through receptor binding, meaning molecules of different shapes and sizes bonded to specific parts of the nose like puzzle pieces, triggering smell recognition in the brain. But recently, biophysicist Luca Turin has proposed the nose detects smell through quantum vibrations. Turin suggests the frequency at which different molecules vibrate helps the nose identify them as different scents. The theory could explain why molecules of the same shape smell quite differently. Intriguing as it is, this new theory hasn’t been tested enough to be universally accepted.

2. Our big brains might have caused our noses to protrude.

As anyone who’s been to a zoo probably knows, great apes (the closest human ancestors) have flat nasal openings—and researchers found that type of nose is far more effective at inhaling air than the human version. So what’s up with ours? Scientists think the shape might be a by-product of our big brain. The growing cerebellum forced human faces to become smaller, which probably affected the nose as well.

3. Women's noses are more sensitive than men's.

In the battle of the sexes, women’s noses come out on top. When tested for odor detection and identification, women score consistently higher than men. This might have something to do with the size of their olfactory bulb, a structure in the brain that helps humans identify smells. One study found that women have, on average, 43 percent more cells in their olfactory bulb than men do—meaning they can smell more smells.

4. Holding your nose really does help you swallow something distasteful.

Think you like chocolate just because it tastes good? Think again. Smell is responsible for 75 to 95 percent of flavor, which explains why plugging your nose helps you swallow something unappetizing. More recently, chefs and neurologists have teamed up to create meals for cancer patients and others with a diminished sense of smell, such as the elderly. Cooking meals tailored to the smell-less could help stave off depression and improve the appetite without relying on sugar and salt.

5. Surgeons can regrow damaged noses.

When people have cancer or are in an accident, the nose can become infected or even be completely destroyed. But fear not. Plastic surgeons have a way to regrow your nose—on your forehead. Using cartilage from the ribs and tissue expanders that allow the skin to stretch and grow, a new nose can be formed to replace the old one. And while a nose growing out of your forehead looks odd, it's actually one of the best places for a new nose to grow. The forehead's blood vessels can be harnessed to help grow the tissue, and removing the new nose only leaves a small scar [PDF]. Doctors have performed the procedure in the U.S., China, and India.

6. Your nose can sense more than smells.

The nose doesn’t just translate odors in the nasal passage—the tip is also full of nerves that detect pain and temperature. This helps us “smell” non-odor smells. Even people who can no longer smell things with their olfactory system can detect substances like menthol, the minty compound that makes your skin tingle. (Unfortunately, they can’t detect pure scents like vanilla.)

7. About 20,000 liters of air pass through the nose every day.

The average adult breathes around 20,000 liters of air every day, which keeps the nose quite busy. As the first line of defense for the lungs, the nose filters out small particles like pollen and dust. It also adds moisture to the air and warms it so the lungs are saved from any irritation.

8. Anosmia is just one of several smell disorders affecting the nose.

There are plenty of things that can go wrong in your nose. Allergic rhinitis, sinus infections, and broken noses are just a few. But perhaps less well known are disorders that affect the nose’s ability to smell. Anosmia is the complete inability to detect odors and can be caused by illness, aging, radiation, chemical exposure, or even genetics. Equally bizarre are parosmia and phantosmia: The former changes your perception of smells, and the latter creates the perception of smells that don’t exist. Luckily, only 1 or 2 percent of North Americans suffer from any smell disorders.

Why Do We Get Shivers Up Our Spines?

iStock.com/martin-dm
iStock.com/martin-dm

Picture this: You're sitting on your couch in the dark alone, watching a scary movie. The killer is walking toward an unsuspecting victim, then suddenly jumps out at her. In that moment, the hairs on your body stand up, and you get a shiver down your spine. When you go for a walk on a crisp morning, the same thing happens. When the music swells during your favorite song, you get the shivers again, this time with the little goosebumps on your arms that appear when you get that sensation.

There's a good reason for shivers and goosebumps: they're your body's response to emotion or stress. We got this from our animal ancestors. When they were cold, the hair on their bodies would stand up—the movement of the arrector pili muscle would cause the skin to contract, raising each hair—to provide an extra layer of insulation. This response is also in play when animals feel threatened: their natural reaction is to try to look bigger than their attacker, so their skin and hair expand to play up that effect. The part of the brain called the hypothalamus is what controls this reaction.

So why do goosebumps—also known as cutis anserina or piloerection—appear, aside from the functional purpose of looking larger or creating insulation? It's because our emotions are also connected with the hypothalamus, so sometimes goosebumps are just our body reacting to our brain's signals of intense emotion.

When we feel things like love, fear, or sadness, the hypothalamus sends a signal to our bodies that produces adrenaline in our blood. The signal triggers the arrector pili muscles to contract, and then we have goosebumps caused by emotion. The sudden adrenaline rush may also cause sweaty palms, tears, increased blood pressure, or shivers.

When we listen to music and get shivers, it is a mixture of subjective emotions toward the music and physiological arousal. If we hear a song we get excited about, or a song that makes us sad, the hypothalamus reacts to the sudden change in emotion and we physically feel the shiver along our spine.

This article was republished in 2019.

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