12 Facts About Fibromyalgia

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iStock.com/spukkato

To people living with fibromyalgia, the symptoms are all too real. Muscle tenderness, full-body pain, and brain fog make it hard to function—and getting a restful night’s sleep isn’t much easier. To the frustration of patients, other aspects of the chronic condition—such as what causes it, how to diagnose it, and how to treat it—are more of a mystery. But after decades of rampant misconceptions, we know more facts about fibromyalgia than ever before.

1. SYMPTOMS FEEL DIFFERENT FOR EVERYONE.

Symptoms of fibromyalgia can vary widely. The defining characteristic of the condition is widespread pain, or pain felt throughout the entire body, but how often this pain occurs and how intensely it’s felt is different in each patient. Some people may feel pain reminiscent of a sunburn, a pins-and-needle sensation, sharp stabbing, or some combination of the above. Beyond pain, the condition can come with fatigue, disrupted sleep, depression and anxiety, and trouble focusing (known as “fibro fog").

2. IT AFFECTS MOSTLY WOMEN.

Most fibromyalgia patients are female, making it more prevalent in women than breast cancer. Not only are women more likely to have fibromyalgia than men, but they report experiencing the symptoms more acutely as well. Researchers still aren’t sure why the condition has a disproportionate impact on women, but they speculate that because the diagnosis is most common during a woman's fertile years, it may have something to do with estrogen levels. Some experts also suspect that the condition may be under-diagnosed in men because it’s often labeled a woman’s problem.

3. IT’S RARE.

Though it has gained visibility in recent years, your chances of experiencing fibromyalgia are still slim. According to the Centers for Disease Control and Prevention, it affects roughly 4 million adults in the U.S., or 2 percent of the population. Fibromyalgia’s similarity to other mysterious conditions also means it is likely overdiagnosed, so that number may be even lower.

4. MOST PEOPLE GET IT IN MIDDLE AGE.

People who have fibromyalgia tend to develop it well into adulthood. The condition is most common in 30- to 50-year-olds, but people of all ages—including children and seniors—can have it. Fibromyalgia in patients 10 and younger, also called juvenile fibromyalgia, often goes unrecognized.

5. IT’S HARD TO DIAGNOSE.

There’s no one medical test that you can take to confirm you have fibromyalgia. Instead, doctors diagnosis patients who exhibit the condition’s most common symptoms—widespread pain, fatigue, trouble sleeping, and muscle tenderness in certain points on the body—by process of elimination. Polymyalgia rheumatica and hypothyroidism (or an underactive thyroid gland) provoke similar symptoms, and both show up in blood tests. Doctors will usually tests for these conditions and others before diagnosing a person with fibromyalgia.

6. THE NAME IS RELATIVELY NEW.

People have suffered from fibromyalgia for centuries, but it received its official name only a few decades ago. In 1976, the word fibromyalgia was coined to describe the condition, with fibro coming from fibrous tissue, myo from the Greek word for muscle, and algia from the Greek word for pain. The name replaced fibrositis, which was used when doctors incorrectly believed that fibromyalgia was caused by inflammation (which -itis is used to denote).

7. IT MAY BE ASSOCIATED WITH PTSD.

Health experts have long known that post-traumatic stress disorder can manifest in physical symptoms—now they suspect the disorder is sometimes connected to fibromyalgia. According to a study published in the European Journal of Pain in 2017, 49 percent of 154 female fibromyalgia patients had experienced at least one traumatic event in childhood, and 26 percent had been diagnosed with PTSD. Researchers also saw a correlation between trauma and the intensity of the condition, with subjects with PTSD experiencing more and worse fibromyalgia pain than those without it.

8. IT’S NOT “ALL IN YOUR HEAD.”

As is the case with many invisible illnesses, fibromyalgia patients are often told their symptoms are purely psychological. But findings from a 2013 study suggested what many sufferers already knew: Their pain is more than just a product of mental distress or an overactive imagination. The small study, published in the journal Pain Medicine, found extra sensory nerve fibers around certain blood vessel structures in the hands of 18 of 24 female fibromyalgia patients compared to 14 of 23 controls. The study proposed that the nerve endings—once thought to merely regulate blood flow—may also be able to perceive pain, an idea that could help dispel a harmful myth surrounding the condition.

9. IT’S CONNECTED TO ARTHRITIS, CHRONIC FATIGUE SYNDROME, AND IBS.

For many patients, fibromyalgia isn’t the only chronic condition they suffer from. Fibromyalgia has been linked to chronic fatigue syndrome, irritable bowel syndrome, sleep apnea, migraines, rheumatoid arthritis, and other medical problems. In some cases, as with chronic fatigue syndrome, the two conditions have such similar symptoms that their diagnostic criteria overlaps. Others conditions like irritable bowel syndrome are related to fibromyalgia—not confused with it.

10. IT'S PROBABLY NOT GENETIC—BUT IT CAN CLUSTER IN THE FAMILIES.

If you're closely related to someone with fibromyalgia, you're more likely to have it yourself. Studies have shown that the diagnosis tends to cluster in families. At first this seems to suggest that the condition is genetic, but scientists have yet to identify a specific gene that's directly responsible for fibromyalgia. The more likely explanation for the trend is that members of the same family experience the same environmental stressors that can trigger the symptoms, or they share genes that are indirectly related to the issue.

11. ANTIDEPRESSANTS CAN HELP ...

Since we don't know what causes fibromyalgia, it's hard to treat. But patients are often prescribed antidepressants to ease their symptoms. These medications have been shown to alleviate some of the most debilitating hallmarks of the condition, such as general pain and restless nights. Doctors who support antidepressants as a fibromyalgia treatment are quick to note that that doesn’t make the condition a mental disorder. While these drugs can lift the depressed moods that sometimes come with fibromyalgia, they also function as painkillers.

12. ... AND SO CAN EXERCISE.

One of the most common pieces of advice fibromyalgia patients get from doctors is to exercise. Hitting the gym may seem impossible for people in too much pain to get off the couch, but physical activity—even in small doses—can actually alleviate pain over time. It also works as treatment for other fibromyalgia symptoms like depression and fatigue.

Pet Obesity is Causing Big Health Problems, According to a New Report

iStock/dennisvdw
iStock/dennisvdw

If you’ve recently picked up your cat and felt your back give out, your furry friend may be among the 60 percent of the feline population that’s overweight. Dogs are also getting chubbier: about 56 percent of pet pooches are obese.

According to Banfield Pet Hospital, America's largest general veterinary practice with more than 1000 hospitals nationwide, those fat cats and chunky puppies are at risk for chronic health issues. In a new report, the hospital finds that osteoarthritis (OA) in pets is on the rise, with a 66 percent increase in dogs and a 150 percent increase in cats over the past 10 years.

Osteoarthritis is a kind of arthritis caused by inflammation or damage in joint tissue. Genetics, injury, or bone abnormalities can all be factors. The disease is chronic and degenerative and can make it difficult for pets to move around as they get older.

Excess weight can both precede OA and make it worse. When a pet is overweight, they can develop chronic pain that leads to stress on joints. If they already have OA, that joint discomfort can prevent them from being active, leading to weight gain. That worsens the condition, and the cycle continues.

A dog is 2.3 times more likely to be diagnosed with OA if it's obese, while cats are 1.2 times more likely. Dogs suffering from the condition tend to display symptoms like putting their weight off to one side when sitting, avoiding stairs, or appearing uninterested in playing. Cats might have loose or matted hair because they can't maneuver to groom certain parts of their body.

Although OA can be seen at any age, it’s often mistaken for old age and a pet slowing down naturally. If you notice your pet is either soft around the middle or moving more slowly, it’s best to see a veterinarian. Pets who are overweight or suffering from OA—or both—can benefit from treatments like special diets.

12 Facts About Diabetes Mellitus

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iStock/mthipsorn

Thirty million Americans—about 9 percent of the country's population—are living with diabetes mellitus, or simply diabetes. This chronic condition is characterized by sustained high blood sugar levels. In many patients, symptoms can be managed with insulin injections and lifestyle changes, but in others, the complications can be deadly. Here's what you need to know about diabetes mellitus.

1. There are three types of diabetes.

In healthy people, the pancreas produces enough of the hormone insulin to metabolize sugars into glucose and move the glucose into cells, where it's used for energy.

But people with type 2 diabetes—the most common form of the disease, accounting for about 95 percent of cases—either can't produce enough insulin to transport the sugars, or their cells have become insulin-resistant. The result is a buildup of glucose in the blood (a.k.a. high blood sugar or hyperglycemia). Type 2 diabetes typically develops in adults.

Type 1 diabetes, also known as juvenile diabetes, makes up the remaining 5 percent of chronic cases and most often develops in children and young adults. With this condition, the initial problem isn’t blood sugar levels, but insulin production: The pancreas can’t make enough insulin to process even normal amounts of glucose. The sugar builds up as a result, leading to dangerous concentrations in the bloodstream.

The third form, gestational diabetes, only afflicts pregnant people who weren’t diabetic before their pregnancy. The mother's blood glucose levels usually spike around the 24th week of pregnancy, but with a healthy diet, exercise, and insulin shots in some cases, diabetes symptoms usually can be managed. Blood sugar levels tend to return to normal in patients following their pregnancies.

2. The mellitus in diabetes mellitus means "honey sweet."

Around 3000 years ago, ancient Egyptians described a condition with diabetes-like symptoms, though it wasn't called diabetes yet. It took a few hundred years before the Greek physician Araetus of Cappodocia came up with the name diabetes based on the Greek word for "passing through" (as in passing a lot of urine, a common diabetes symptom). English doctor Thomas Willis tacked on the word mellitus, meaning "honey sweet," in 1675, building on previous physicians' observations that diabetic patients had sweet urine. Finally, in 1776, another English physician named Matthew Dobson confirmed that both the blood and urine of diabetes patients were made sweeter by high levels of glucose in their blood.

3. The cause of one type of diabetes is well understood; the other, not so much.

A person’s lifestyle is a key predictor of developing type 2 diabetes. Factors like being overweight or obese, consuming a high-calorie diet, smoking, and seldom exercising contribute to the risk. Foods and drinks that are high in sugar—soda, candy, ice cream, dessert— may contribute to hyperglycemia, but any food that’s high in calories, even if it's not sweet, can raise blood sugar levels.

In contrast to these well-established factors, medical experts aren’t entirely sure what causes type 1 diabetes. We do know that type 1 is an autoimmune disease that develops when the body attacks and damages insulin-producing cells in the pancreas. Some scientists think that environmental factors, like viruses, may trigger this immune response.

4. Family history also plays a role in diabetes risk.

If a parent or sibling has type 2 diabetes, you are predisposed to developing pre-diabetes and type 2 diabetes. Lifestyle habits explain some of these incidences, since family members may share similar diets and exercise habits. Genetics also play a role, but just because one close relative has diabetes does not mean you're destined to. Research conducted on identical twins, which share identical genes, showed that the pairs have discordant risk. Among twins in which one has type 1 diabetes, the other has only a 50 percent chance of developing it; for type 2, the risk for the second twin is 75 percent at most.

5. Racial minorities are at a higher risk for developing diabetes.

Many racial minority groups in the U.S. have a higher chance of developing type 2 diabetes. Black Americans, Latino Americans, Native Americans, Pacific Islanders, and some groups of Asian Americans are more likely to have pre-diabetes and type 2 diabetes than white Americans. This can be partly explained by the fact that some of these groups also have higher rates of obesity, which is one of the primary risk factors of type 2 diabetes. Socioeconomics may also play a role: One study shows that people with diabetes living in poverty are less likely to visit diabetes clinics and receive proper testing than their middle-income counterparts. According to another study, diabetic people without health insurance have higher blood sugar, blood pressure, and cholesterol rates than insured diabetics. Genetics, on the other hand, don’t appear to contribute to these trends.

6. Diabetes is one of the world's deadliest diseases.

With proper management, people with diabetes can live long, comfortable lives. But if the disease isn’t treated, it can have dire consequences. Diabetics make up the majority of people who develop chronic kidney disease, have adult-onset blindness, and need lower-limb amputations. In the most serious cases, diabetes leads to death. The condition is one of the deadliest diseases in the world, killing more people than breast cancer and AIDS combined.

7. Millions of Americans are pre-diabetic.

According to the CDC, 84 million adults living in the U.S. are pre-diabetic: Their blood sugar is higher than what’s considered safe, but hasn't yet reached diabetic level. In pre-diabetic patients, blood glucose levels after eight hours of fasting fall between 100 and 125 milligrams per deciliter, and diabetic levels are anything above that. People with pre-diabetes are not just at a greater risk for type 2 diabetes, but also for heart disease and stroke. Fortunately, people who are diagnosed with pre-diabetes can take steps to eat a healthier diet, increase physical activity, and test their blood glucose level several times a day to control the condition. In some cases, doctors will prescribe drugs like metformin that make the body more receptive to the insulin it produces.

8. After climbing for decades, rates of diabetes incidence are declining.

In the U.S., the rate of new diagnoses skyrocketed 382 percent between 1988 and 2014. Globally, 108 million people had diabetes in 1980, but by 2014 that number was 422 million.

But thanks to nationwide education and prevention efforts, the trend has reversed in the U.S., according to the CDC. Since peaking in 2009, the number of new diabetes cases in America has dropped by 35 percent. In that same timeframe, the number of people living with diagnosed diabetes in the U.S. has plateaued, suggesting people with the condition are living longer.

9. The first successful treatment for type 1 diabetes occurred in 1922.

Prior to the 20th century, type 1 diabetes was usually fatal. Diabetic ketoacidosis—a toxic buildup of chemicals called ketones, which arise when the body can no longer use glucose and instead breaks down other tissues for energy—killed most patients within a year or two of diagnosis. In searching for way to save children with juvenile (type 1) diabetes, Canadian physician Frederick Banting and medical student Charles Best built on the work of earlier researchers, who had demonstrated that removing the pancreas from a dog immediately caused diabetes symptoms in the animal. Banting and Best extracted insulin from dog pancreases in University of Toronto professor J.J.R. Macleod's lab. After injecting the insulin back into dogs whose pancreases had been removed, they realized the hormone regulated blood sugar levels. On January 11, 1922, they administered insulin to a human patient, and further refined the extract to reduce side effects. In 1923, Banting and Macleod received the Nobel Prize in Medicine for their work.

10. A pioneering physicist discovered the difference between type and and type 1 diabetes.

In the 1950s, physicist Rosalyn Yalow and her research partner Solomon Berson developed a method for measuring minute amounts of substances in blood. Inspired by Yalow's husband's struggle with diabetes, Yalow focused her research on insulin. Their "radioimmunoassay" technology revealed that some diabetes patients were still able to produce their own insulin, leading them to create two separate categories for the disease: “insulin-dependent” (type 1) and “non-insulin-dependent” (type 2). Prior to that discovery in 1959, there was no distinction between the two types. In 1977, Yalow won the 1977 Nobel Prize in Medicine for the radioimmunoassay, one of only 12 female Nobel laureates in medicine.

11. Making one insulin dose once required tons of pig parts.

Insulin is relatively easy to make today. Most of what's used in injections comes from a special non-disease-producing laboratory strain of E. coli bacteria that's been genetically modified to produce insulin, but that wasn't always the case. Until about 40 years ago, 2 tons of pig pancreases were required to produce just 8 ounces of pure insulin. The pig parts were typically recycled from pork farms.

12. A quarter of diabetes patients don’t know they have it.

The symptoms of type 2 diabetes can develop for years before patients think to ask their doctor about them. These include frequent urination, unexplained thirst, numbness in the extremities, dry skin, blurry vision, fatigue, and sores that are slow to heal—signs that may not be a cause for concern on their own, but together can indicate a more serious problem. Patients with type 1 diabetes may also experience nausea, vomiting, and stomach pain.

While serious, the symptoms of diabetes are sometimes easy to overlook. That’s why 25 percent of people with the illness, 7.2 million in the U.S., are undiagnosed. And that number doesn’t even cover the majority of people with pre-diabetes who aren’t aware they’re on their way to becoming diabetic.

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