Allergies Are On the Rise, and Scientists Have a Good Idea Why

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If it seems like everyone around you is constantly sneezing and sniffling, it might be because allergies are on the rise. As New Scientist reports, several studies seem to indicate this is an ongoing trend. While allergies were rare before the mid-20th century, they’re now a common occurrence in children and adults alike. According to the Food Allergy Research and Education Organization, 15 million people in the U.S. have a food allergy.

To make matters worse, some of the fastest-developing countries are seeing a steady increase in allergies, especially in China. Asthma rates among children in Shanghai rose from 2 percent to 10 percent between 1990 and 2011.

So what exactly is at play here? Scientists think the rise in allergies has much to do with how drastically our lifestyles have changed in the last century. In particular, many modern people spend most of their days—and lives—indoors, which wasn’t always the norm. Spending time outdoors at an early age helps expose you to certain microbes “that have helped hone the human immune system for millennia,” New Scientist notes.

For that reason, children who grow up on farms are less likely to develop allergies. However, scientists still don’t understand exactly how these microbes help prevent our immune system from producing Immunoglobulin E, which is released in response to an allergen coming into contact with the body.

Fortunately, there are ways to keep your allergies under control, even if you can't prevent them entirely. Showering before you sleep, using an air purifier, and keeping pets off your bed are just a few of the quick tips you can try.

[h/t New Scientist]

FDA Recalls Thyroid Medications Due to Contamination Risk

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Hypothyroid medications manufactured by Westminster Pharmaceuticals have been recalled after it was discovered that one of the company’s Chinese suppliers failed to meet U.S. Food and Drug Administration (FDA) standards, CNN reports.

The oral tablets contain levothyroxine (LT4) and liothyronine (LT3), which are both synthetic hormones used to treat thyroid conditions.

The medicine was recalled as a precaution after it was discovered during a 2017 FDA inspection that the Chinese supplier in question, Sichuan Friendly Pharmaceutical Co., was not practicing good manufacturing practices.

However, patients with serious thyroid conditions shouldn’t throw out their pills just yet. No adverse effects from the medication have been reported, and the risk of not taking the medication outweighs the risk of taking a recalled pill.

According to the FDA, “Because these products may be used in the treatment of serious medical conditions, patients taking the recalled medicines should continue taking their medicine until they have a replacement product.”

For more information on the specific lots and products in question, visit the FDA’s website.

[h/t CNN]

A 'Zombie Gene' Might Be the Reason Elephants Rarely Get Cancer

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When it comes to cancer rates in the animal kingdom, elephants are an anomaly. As Popular Science notes, cancer should be more common among larger species, but with elephants, that simply isn’t the case. Only about 5 percent of elephants die from cancer, compared to 11 to 25 percent of humans.

In a new study, published in Cell Reports, University of Chicago researchers found what’s believed to be the genetic source of elephants’ cancer immunity. Elephants, like all mammals, have a gene called LIF that is known to suppress tumors. Humans have one copy of this gene, but elephants have 10 copies, which have developed over 80 million years of evolution. However, only one of those copies, called LIF6, is functional in elephants.

The other LIF copies are essentially dead because they lack a specific piece of DNA to make them function. At some point during the evolutionary process, the LIF6 gene copy turned back on, but scientists don’t know why or when this occurred. This “zombie gene” helps kill mutated cells, in true Night of the Living Dead fashion.

“This reanimation of LIF6 occurred perhaps over 59 million years,” Joshua Schiffman, who studies cancer in elephants but was not involved in the study, told Popular Science. “That’s an amazingly long period of time for nature to modify and perfect an anticancer mechanism.”

Scientists aren’t yet sure how this could be applied to cancer research in humans, but they say it’s a promising start and a creative approach to the problem. While these findings are still fresh and need to be duplicated, it raises the possibility of creating a drug that mimics the function of LIF6.

[h/t Popular Science]

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