What Would Happen If a Person Received a Transfusion Using a Blood Type Other Than Their Own?

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iStock

Ivan Zeitz:

That depends on what type of blood was given and the recipient’s blood type.

There are three major antigens (things on the outside of blood cells that cause allergic reactions). The antigens are A, B, and O. There are two copies. The combos are OO, AO, BO, and AB. They are referred to as O, A, B, and AB for the sake of simplicity.

Type O is tolerated by everyone. Type O blood is “universal donor” and prized. Type A blood is tolerated by A and AB recipients. Type B is tolerated by B and AB recipients. Type AB blood is only tolerated by AB recipients … AB types are “universal recipients.”

So what happens depends on chance:

  • If a person with AB gets anything different, it does not matter.
  • If a person with O gets anything different, that’s likely a huge problem called a major hemolytic transfusion reaction.

In a major hemolytic transfusion reaction, the recipient’s immune system vigorously attracts the donated blood. The cells are ripped apart, tons of bad chemicals are released, and the person gets super sick. The kidneys can fail ... first reddish urine then shutdown. The person can develop a severe flu-like illness. They can go into shock and ultimately die. Mortality is high without treatment and considerable even with it.

This is why a mix up is a potentially tragic error.

This post originally appeared on Quora. Click here to view.

Why Do We Call a Leg Cramp a Charley Horse?

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iStock.com/Jan-Otto

If you’re unlucky enough to have experienced a charley horse—a painful muscle spasm or cramp in your leg—then you may have found yourself wondering what this nonsensical phrase even means. Who is this Charley character? Where did he come from? And what does he know about my pain?

Like the words flaky and jazz, this term likely entered the language from the baseball field. While the idiom’s etymology isn’t 100 percent certain, archived newspaper articles suggest it was coined by a baseball player in the 1880s. We just don’t know which player said it first, or why.

According to a January 1887 article in the Democrat and Chronicle, the phrase was well-known to baseball players at the time—but to the average person, charley horses were as enigmatic as “an Egyptian hieroglyphic.” That year, charley horses were mentioned in a slew of newspapers across America, and some attempted to tackle the phrase’s murky origin. “Nearly every sporting journal gives a different version as to how the term charley horse originated in baseball circles,” the Oakland Daily Evening Tribune reported at the time.

The likeliest tale, according to the paper, centered around John Wesley "Jack" Glasscock, a shortstop who at the time was playing for Indianapolis. At some point a few years earlier, the player had strained a tendon in his thigh during a game and afterwards went home to his farm, where his father looked after a lame old horse called a "Charley horse." When the senior Glasscock saw his son limping along, he reportedly exclaimed, “Why, John, my boy, what is the matter; you go just like the old Charley horse?” John supposedly shared the funny turn of phrase with his teammates, and from there it spread. Similar accounts were reported in other newspapers, but they were attributed to various other players.

Other reports say the phrase has nothing to do with a live animal, but rather the fact that an injured player, while running, resembles a rocking horse or a child riding astride a wooden hobby horse.

The New Dickson Baseball Dictionary by Paul Dickson details a few other theories. In two versions of the same basic tale, Orioles or Chicago Cubs players went to the races and bet on a horse named Charlie who "pulled up lame in the final stretch." The next day, a player pulled a tendon in his leg and was said to resemble “our old Charlie horse.”

Alternatively, its origin may relate to an old workhorse that was tasked with pulling a roller across the infield. “Often in the 1800s, old workhorses kept on the grounds of ballparks were called Charley. The movements of the injured, stiff-legged ballplayers were likened to the labored plodding of these old horses, and the injury itself eventually became known as a ‘charley’ or ‘charley horse,'" Tim Considine wrote in 1982's The Language of Sport.

It also appears that charley horse originally implied a much more serious injury—or perhaps there was a bit of hysteria surrounding a condition that seemed new and scary in the late 19th century. The Democrat and Chronicle described a charley horse as a “giving way of one of the small tendons of the leg” and said an injured baseball player might need an entire season to recover. Another article from 1887 said ballplayer George Van Haltren’s relatives were worried he would get a charley horse, “although they do not know what that is.” He was said to have been “very fortunate” because he had “not yet encountered the terrible charley horse.”

For comparison, Healthline.com now says charley horses “are generally treatable at home” by stretching, massaging, or icing the afflicted area, although the muscle pain can linger for up to a day in some cases. So there you have it. We may never know the exact etymology of the charley horse, but the next time you get a sharp pain in your leg, you can thank an old-timey ballplayer for making your struggle sound so silly.

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What's the Difference Between Straw and Hay?

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iStock.com/dusipuffi

The words straw and hay are often used interchangeably, and it's easy to see why: They're both dry, grassy, and easy to find on farms in the fall. But the two terms actual describe different materials, and once you know what to look for, it's easy to tell the difference between them.

Hay refers to grasses and some legumes such as alfalfa that are grown for use as animal feed. The full plant is harvested—including the heads, leaves, and stems—dried, and typically stored in bales. Hay is what livestock like cattle eat when there isn't enough pasture to go around, or when the weather gets too cold for them to graze. The baled hay most non-farmers are familiar with is dry and yellow, but high-quality hay has more of a greenish hue.

The biggest difference between straw and hay is that straw is the byproduct of crops, not the crop itself. When a plant, such as wheat or barley, has been stripped of its seeds or grains, the stalk is sometimes saved and dried to make straw. This part of the plant is lacking in nutrients, which means it doesn't make great animal fodder. But farmers have found other uses for the material throughout history: It what's used to weave baskets, thatch roofs, and stuff mattresses.

Today, straw is commonly used to decorate pumpkin-picking farms. It's easy to identify (if it's being used in a way that would be wasteful if it were food, chances are it's straw), but even the farms themselves can confuse the two terms. Every hayride you've ever taken, for example, was most likely a straw-ride.

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