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The First Shot to Stop Chronic Migraines Just Secured FDA Approval

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Migraine sufferers unhappy with current treatments will soon have a new option to consider. Aimovig, a monthly shot, just received approval from the Food and Drug Administration and is now eligible for sale, CBS News reports. The shot is the first FDA-approved drug of its kind designed to stop migraines before they start and prevent them over the long term.

As Mental Floss reported back in February before the drug was cleared, the new therapy is designed to tackle a key component of migraine pain. Past studies have shown that levels of a protein called calcitonin gene–related peptide (CGRP) spike in chronic sufferers when they're experiencing the splitting headaches. In clinical trials, patients injected with the CGRP-blocking medicine in Aimovig saw their monthly migraine episodes cut in half (from eight a month to just four). Some subjects reported no migraines at all in the month after receiving the shot.

Researchers have only recently begun to untangle the mysteries of chronic migraine treatment. Until this point, some of the best options patients had were medications that weren't even developed to treat the condition, like antidepressants, epilepsy drugs, and Botox. In addition to yielding spotty results, many of these treatments also come with severe side effects. The most serious side effects observed in the Aimovig studies were colds and respiratory infections.

Monthly Aimovig shots will cost $6900 a year without insurance. Now that the drug has been approved, a flood of competitors will likely follow: This year alone, three similar shots are expected to receive FDA clearance.

[h/t CBS News]

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Netherlands Officials Want to Pay Residents to Bike to Work
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Thinking about relocating to the Netherlands? You might also want to bring a bike. Government officials are looking to compensate residents for helping solve their traffic congestion problem and they want businesses to pay residents to bike to work, as The Independent reports.

Owing to automobile logjams on roadways that keep drivers stuck in their cars and cost the economy billions of euros annually, Dutch deputy infrastructure minister Stientje van Veldhoven recently told media that she's endorsing a program that would pay employees 19 cents for every kilometer (0.6 miles) they bike to work.

That doesn't sound like very much, but perhaps citizens who need to trek several miles each way would appreciate the cumulative boost in their weekly paychecks. For employers, the benefit would be a healthier workforce that might take fewer sick days and reduce parking needs.

Veldhoven says she also plans on designing a program that would assist employers in supplying workers with bicycles. The goal is to have 200,000 people opting for manual transportation over cars. If the program proceeds, it might find a receptive population. The Netherlands is already home to 22.5 million bikes, more than the 17.1 million people living there. In Amsterdam, a quarter of residents bike to work.

There's no timeline for implementing the pay-to-bike plan, but early trial studies indicate that the expense might not have to be a long-term prospect. Study subjects continued to bike to work even after the financial rewards stopped.

[h/t The Independent]

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New Health-Monitoring Litter Box Could Save You a Trip to the Vet
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Unsure if your cat is sick or just acting aloof per usual? A “smart toilet” for your fur baby could help you decide whether a trip to the vet is really necessary.

Enter the Pet Care Monitor: More than a litter box, the receptacle is designed to analyze cat urine for health issues, The Asahi Shimbun in Tokyo reports. Created by the Japan-based Sharp Corporation—better known for consumer electronics such as TVs, mobile phones, and the world's first LCD calculator—the product will be available for purchase on the company’s website starting July 30 (although shipping limitations may apply).

Sensors embedded in the monitor can measure your cat’s weight and urine volume, as well as the frequency and duration of toilet trips. That information is then analyzed by an AI program that compares it to data gleaned from a joint study between Sharp Corp and Tottori University in Japan. If there are any red flags, a report will be sent directly to your smartphone via an application called Cocoro Pet. The monitor could be especially useful for keeping an eye on cats with a history of kidney and urinary tract problems.

If you have several cats, the company offers sensors to identify each pet, allowing separate data sets to be collected and analyzed. (Each smart litter box can record the data of up to three cats.)

The Pet Care Monitor costs about $225, and there’s an additional monthly fee of roughly $3 for the service. Sharp Corporation says it will continue developing health products for pets, and it has already created a leg sensor that can tell if a dog is nervous by measuring its heart and respiratory rates.

[h/t The Asahi Shimbun]

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