A Year in Space Changed How Astronaut Scott Kelly's Genes Behaved

NASA
NASA

After spending 342 consecutive days onboard the International Space Station from 2015 to 2016, astronaut Scott Kelly now holds the record for longest single space mission by an American. But his "One-Year" study with NASA was about more than breaking records: Its purpose was to show how prolonged time in orbit would effect Kelly's genetic makeup compared to that of his identical twin brother on Earth. Now, following recent evaluations of the two men, it appears that Scott Kelly's gene expression was significantly altered by his time in space, Space.com reports.

NASA announced the most recent findings from its Twins Study ahead of a more comprehensive paper combining the work of multiple teams of researchers that is slated for later in 2018. Like his brother Scott, Mark is also an astronaut, making the pair the only twin astronauts in history. So when NASA was looking for a way to study the long-term effects of space life, the siblings were a perfect fit.

As Scott was sending tweets and blowing bubbles on the ISS, Mark stayed on Earth to serve as the control. Biological samples taken from both subjects before, during, and after the space flight showed some dramatic differences. According to an investigation conducted by Susan Bailey of Colorado State University, Scott's telomeres, the protective "cap" at the ends of chromosomes that shorten as we age, got longer in space. The telomeres began shrinking back to preflight levels, however, a few days after Scott's return to Earth. Scott was subjected to regular exercise and a restricted diet aboard the ISS, so the new lifestyle may explain the sudden telomere boost.

Other genetic differences stuck around even months after landing. "Although 93 percent of genes' expression returned to normal post-flight, a subset of several hundred 'space genes' were still disrupted after return to Earth," acccording to a NASA press release. About 7 percent of Scott's genes may show longer-term changes, included the genes associated with DNA repair, immune health, bone formation, hypoxia (an oxygen deficiency in the tissues) and hypercapnia (excessive carbon dioxide in the bloodstream).

A long list of factors, like radiation, caloric restriction, and zero gravity, may have contributed to the results. NASA plans to use these findings to develop countermeasures against these effects, which will be essential if the agency plans to send humans to Mars, a journey that could take three times as long as Scott Kelly's ISS mission.

[h/t Space.com]

Editor's note: We updated the headline and one line of this story to more accurately reflect the research findings. We apologize for the error. 

8 Facts About David Bowie's 'Space Oddity'

Express/Express/Getty Images
Express/Express/Getty Images

Fifty years ago, on July 24, 1969, astronauts walked on the Moon for the first time. Just a few weeks earlier, another space-age event had rocked the world: David Bowie’s single “Space Oddity” hit airwaves. The song, whose lyrics tell the story of an astronaut’s doomed journey into space, helped propel the artist to icon status, and five decades later, it’s still one of his most popular works. In honor of its 50th anniversary, here are some facts about the stellar track.

1. "Space Oddity" was inspired by 2001: A Space Odyssey.

Many listeners assumed that "Space Oddity" was riffing on the Apollo 11 Moon landing of 1969, but it was actually inspired by a Stanley Kubrick film released a year earlier. Bowie watched 2001: A Space Odyssey multiple times when it premiered in theaters in 1968. “It was the sense of isolation I related to,” Bowie told Classic Rock in 2012. “I found the whole thing amazing. I was out of my gourd, very stoned when I went to see it—several times—and it was really a revelation to me. It got the song flowing.”

2. "Space Oddity" was also inspired by heartbreak.

The track was also partly inspired by the more universal experience of heartbreak. Bowie wrote the song after ending his relationship with actress Hermione Farthingale. The break inspired several songs, including “Letter to Hermione” and “Life on Mars,” and in “Space Oddity,” Bowie’s post-breakup loneliness and melancholy is especially apparent.

3. "Space Oddity" helped him sign a record deal.

In 1969, a few years into David Bowie’s career, the musician recorded a demo tape with plans to use it to land a deal with Mercury Records. That tape featured an early iteration of “Space Oddity,” and based on the demo, Mercury signed him for a one-album deal. But the song failed to win over one producer. Tony Visconti, who produced Bowie’s self-titled 1969 album, thought the song was a cheap attempt to cash in on the Apollo 11 mission, and he tapped someone else to produce that particular single.

4. The BBC played "Space Oddity" during the Moon landing.

"Space Oddity" was released on July 11, 1969—just five days before NASA launched Apollo 11. The song doesn’t exactly sound like promotional material for the mission. It ends on a somber note, with Major Tom "floating in a tin can" through space. But the timing and general subject matter were too perfect for the BBC to resist. The network played the track over footage of the Moon landing. Bowie later remarked upon the situation, saying, "Obviously, some BBC official said, 'Oh, right then, that space song, Major Tom, blah blah blah, that’ll be great. 'Um, but he gets stranded in space, sir.' Nobody had the heart to tell the producer that."

5. David Bowie recorded an Italian version of "Space Oddity."

The same year "Space Oddity" was released, a different version David Bowie recorded with Italian lyrics was played by radio stations in Italy. Instead of directly translating the English words, the Italian songwriter Mogul was hired to write new lyrics practically from scratch. "Ragazzo Solo, Ragazza Sola" ("Lonely Boy, Lonely Girl") is a straightforward love song, and Major Tom is never mentioned.

6. Major Tom appeared in future songs.

Major Tom, the fictional astronaut at the center of "Space Oddity," is one of the most iconic characters invented for a pop song. It took a decade for him to resurface in David Bowie’s discography. In his 1980 single "Ashes to Ashes," the artists presents a different version of the character, singing: "We know Major Tom's a junkie/Strung out in heaven's high/Hitting an all-time low." Bowie also references Major Tom in "Hallo Spaceboy" from the 1995 album Outside.

7. "Space Oddity" is featured in Chris Hadfield's ISS music video.

When choosing a song for the first music filmed in space, Canadian astronaut Chris Hadfield naturally went with David Bowie’s out-of-this-world anthem. The video above was recorded on the International Space Station in 2013, with Hadfield playing guitar and singing from space and other performers providing musical accompaniment from Earth. Some lyrics were tweaked for the cover. Hadfield mentions the "Soyuz hatch" of the capsule that would eventually shuttle him to Earth.

8. "Space Oddity" played on the Tesla that Elon Musk sent to space.

Dummy in Tesla roadster in space with Earth in background.
SpaceX via Getty Images

In 2018, Elon Musk used SpaceX's Falcon Heavy rocket to launch his Tesla Roadster into space. The car was decked out with pop culture Easter eggs—according to Musk, "Space Oddity" was playing over the car’s radio system during the historic journey. The dummy’s name, Starman, is the name of another space-themed song on Bowie's 1972 masterpiece The Rise and Fall of Ziggy Stardust and the Spiders from Mars.

The Washington Monument Is Transforming Into a Full-Scale Saturn V Rocket for the 50th Anniversary of the Apollo 11 Moon Landing

The Saturn V rocket takes off on July 16, 1969.
The Saturn V rocket takes off on July 16, 1969.

Where better to celebrate the 50th anniversary of the first Moon landing than in front of a revered national monument that also happens to resemble a giant rocket?

Next week, DCist reports, the Smithsonian National Air and Space Museum will project an image of the 363-foot-tall Saturn V rocket that launched Buzz Aldrin, Neil Armstrong, and Michael Collins into space on July 16, 1969, onto the 555-foot-tall Washington Monument. Underneath the monument, flanked by screens playing a 17-minute program about the Moon landing, will be a 40-foot-wide replica of the iconic Kennedy Space Center countdown clock that NASA has called “one of the most-watched timepieces in the world.”

Illustration of the Saturn V rocket projected onto the Washington Monument
An illustration of what the Saturn V projection will look like on the Washington Monument.
Smithsonian National Air and Space Museum

Projecting an image onto an irregular object is a little more complicated than doing so on a run-of-the-mill, rectangular movie screen. The process is called projection mapping, which uses augmented reality to conform the projection to the object, making it seem like the projection is actually just part of the object. 59 Productions, the company behind this program, also created the video design for London’s 2012 Olympic Games opening ceremony and won a 2015 Tony Award for the video design of Christopher Wheeldon’s stage revival of An American in Paris.

So who exactly has to approve transforming one of our nation’s most famous monuments into a really tall, skinny optical illusion? In this case, the House of Representatives, the Senate, the secretary of the interior, and the president himself. Both houses of Congress unanimously passed the bipartisan resolution, H.J. Res. 60 [PDF], in mid-June, and the president signed it on July 5.

According to Ellen Stofan, director of the Smithsonian National Air and Space Museum, the larger-than-life nature of the setting befits the occasion. “The Washington Monument is a symbol of our collective national achievements and what we can and will achieve in the future,” she told DCist. “It took 400,000 people from across the 50 states to make Apollo a reality. This program celebrates them, and we hope it inspires generations too young to have experienced Apollo firsthand to define their own moonshot.”

You can see the Saturn V projection from 9:30 p.m. to 11:30 p.m. on July 16, 17, and 18. The best view is on the National Mall in front of the Smithsonian Institution Building (also known as the “Castle”) between 9th and 12th streets. The entire program, titled “Apollo 50: Go for the Moon,” will run at 9:30 p.m., 10:30 p.m., and 11:30 p.m. on Friday, July 19, and Saturday, July 20.

[h/t DCist]

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