4 Diseases Caused by a Lack of Essential Vitamins and Minerals

iStock
iStock

Companies pushing products with added vitamins and minerals can fool people into thinking that they’re eating a “healthy” food when they’re not—but it’s not like those vitamins and minerals are there for no reason. For much of human history, diseases of nutrient deficiency were the norm, and in some parts of the world, they still persist. Even into the 20th century, conditions caused by a lack of certain vitamins or minerals were endemic to North America and Europe. Artificially added nutrients may not make a food “healthy,” but they do stave off several debilitating, and sometimes fatal, diseases of malnutrition. Here are a few of those maladies.

1. Scurvy

The disease of pirates: the grey-death. Scurvy is caused by a lack of vitamin C, whose chemical name, ascorbic acid, is derived from the Latin term for scurvy, scorbutus. Even though the disease was known since ancient times (described by Hippocrates around 400 BCE), it was not a scourge to those who were largely land-bound. Even though its causes were unknown, many cultures realized that eating certain herbs could reverse the symptoms, and as long as there was access to fresh food, it was generally kept under control.

Scurvy didn’t become a significant problem until the Age of Discovery (beginning in the 15th century), when people at sea were not able to access that much-needed fresh food for months at a time. Preserved meats and carbohydrates contained no vitamin C, and unlike most animals, the human body is not able to create vitamin C on its own.

The early symptoms of scurvy include spongy gums, pain in the joints, and blood spots appearing under the skin. As the disease progressed, the teeth would become loose, extreme halitosis (bad breath) would develop, the afflicted would become too weak to walk or work, be in too much pain to eat, and would die “mid-sentence,” often from a burst blood vessel. Many of the early explorers lost great numbers of men to scurvy: Vasco de Gama lost 116 out of 170 men in 1499, and in 1520, Magellan lost 208 out of 230. A few deaths were attributable to other causes, but the vast majority were due to scurvy.

Despite not being able to pinpoint the exact cause of scurvy, in the 18th century, naval physician James Lind was able to prove, in what’s considered to be the first controlled scientific experiment, that scurvy could be prevented (and cured) by incorporating citrus fruits such as limes and oranges into the diet of sailors. Although his findings weren’t widely accepted at first, the British Navy eventually began issuing standard rations of lemon juice, and later, limes, to their sailors—which gave rise to the term “limey” in reference to the British.

These days, scurvy is an extremely rare condition, almost exclusively caused by someone eating a completely unvaried diet. In most cases, high levels of oral supplementation of vitamin C are enough to reverse the condition in a matter of weeks, and death by scurvy is almost unheard of.

2. Rickets

This condition is brought on by a lack of vitamin D, which causes the body to be unable to absorb or deposit calcium. Less commonly, it can also be caused by a lack of calcium or phosphorus, but vitamin D deficiency is by far the most common cause. Unlike vitamin C, the human body is able to produce vitamin D, but only if it has the metabolic precursors available to it.

When the skin is exposed to ultraviolet light (such as from the sun), cholesterol in the skin reacts and forms cholecalciferol, which is then processed in the liver and kidneys to create the active form of vitamin D. Even with a nominally healthy diet, without enough sun exposure, the body can’t produce the vitamin D precursors on its own. This is actually re-emerging as a health concern among some increasingly-indoor groups of people, and is one of the few hypovitaminosis (lack of vitamin) conditions not considered to be a “disease of the past.” Luckily, when the deficiency is recognized, cholecalciferol can be directly taken as a vitamin supplement or acquired from eating organ meats and oils, such as cod liver oil, allowing the body to resume producing vitamin D.

Rickets is a condition of children, as the deficiency’s most severe effects are on developing bones; in adults, “bone-softening,” or osteomalacia, can be caused by the same vitamin deficiency. But in adults, it both takes significantly longer to develop and tends to cause tip-off signs that something is wrong before bone warping sets in, such as extreme pain in the bones, and unexplained muscle weakness. In children, especially those that don’t or can’t receive regular check-ups, deformity and debilitation by the deficiency is often only noticed after significant damage has been done to their developing skeletons.

The most telling symptoms of rickets are at the epiphyses (growth plates) of bones: The body is unable to lengthen bones by depositing calcium, and ends up with bones that flare outward in a “cupping” appearance. This leads to costochondral swelling, or what’s known as the “rachitic rosary” along the ribcage of the child, as well as widened wrists and “thick” joints. Before widened wrists or rachitic rosary appears, the softening of the skull bones can lead to “Caput Quadratum”—a square-headed appearance, and often the first sign of skeletal growth problems. If left untreated, rickets also can cause an extremely curved back, stunted growth, and frequent fractures—all of which can lead to permanent and debilitating deformity.

3. Beriberi

This condition is largely confined to Asia, especially in countries where boiled rice is a staple. The Sinhalese term “beri-beri” means, “I cannot, I cannot,” and derives from the inability to perform even the simplest of tasks once the polyneuritis (nerve inflammation) caused by the deficiency of vitamin B1 (thiamine) has permanently damaged the neurons, when the condition has progressed to the end-stage.

Although beriberi was known to exist in rice-eating countries several centuries back, its prevalence boomed with the introduction of steam-driven rice-polishing mills from Europe. The superior taste of the milled white rice led many locals to abandon the local (unpolished) brown rice, and in doing so, abandon their primary source of thiamine. From the 1860s to the turn of the 20th century, people whose plant consumption was limited to the polished white rice would often come down with weakness, pain, weight loss, difficulty walking, and emotional disturbances. Beriberi became one of the leading causes of mortality in the region.

In the 1880s, a doctor named Christiaan Eijkman began researching the causes of this epidemic at a laboratory in the Dutch East Indies (now Jakarta, Indonesia), and initially believed that the condition was caused by a bacterial infection. However, after years of study, he came to the conclusion that “white rice is poisonous.” He discovered this by feeding a group of chickens solely white rice, and another group unpolished brown rice. The chickens that ate the white rice came down with beriberi-like symptoms, while the others stayed healthy. Eijkman also discovered that when the chickens fed white rice were subsequently fed brown rice, they recovered from their illness! Later dietary testing on prisoners confirmed his results. Even though he didn’t know the cause of the condition, Eijkman proved that white rice was the culprit, and shared the 1929 Nobel Prize in Medicine for his discovery.

Beriberi is occasionally seen in the modern world, but its primary cause is chronic alcoholism—the poor diets of some chronic alcoholics, combined with the decreased absorption of what thiamine is consumed, leads to symptoms that unfortunately are sometimes left undiagnosed until it’s too late. Recently, beriberi was also seen in Haitian prisons when the prison system began buying imported polished rice from the United States, and stopped feeding their inmates the local brown rice.

4. Pellagra

What causes blistering of the skin in the sun, pale skin, a craving for raw meat, blood dripping from the mouth, aggression, and insanity? If you answered “vampirism,” you’re close—the myth of the vampire may have its roots in the condition known as “pellagra.”

Pellagra is caused by a lack of vitamin B3 (niacin). First identified and commonly diagnosed in the Asturian Empire (now Northern Spain), it was originally called “Asturian leprosy.” However, the condition was seen throughout Europe, the Middle East, and North Africa, wherever a large percentage of food energy was derived from corn, and fresh meat was not available. The area of highest prevalence was Northern Italy, where Francesco Frapoli of Milan called it “pelle agra,” meaning “sour skin.”

It was initially believed that either the corn itself, or some insect associated with corn, was causing pellagra. This belief was reinforced when much of France eliminated corn as a food staple and virtually eradicated the condition. Between the era that corn was introduced to Europe (the early 16th century) and the late 19th century, pellagra was found almost everywhere that poor people subsisted on cornmeal and little else.

Around the turn of the 20th century, people began to notice that despite subsisting on just as much corn as poor Europeans, poor Mesoamerican natives didn’t come down with the condition. It was eventually discovered that this was because the traditional processing of corn in the Americas involved “nixtamalization,” in which the kernels were soaked in limewater before hulling them. The alkali solution freed up the niacin that was present in the grain, but previously inaccessible.

Despite the extensive work of Dr. Joseph Goldberger in the 1910s and 1920s, which proved that pellagra wasn’t caused by a germ but by a dietary deficiency, the condition was occurring in epidemic proportions in the rural Southern US until the 1940s.

Today, pellagra is most common in the poorest regions of the world, especially places that rely upon food aid programs. Some countries still ship unfortified cornmeal rather than corn masa (nixtamalized corn) or fortified cornmeal to developing countries or to their own impoverished populations. China, parts of Africa, Indonesia, and North Korea all have endemic pellagra among their lowest classes.

*******

The discovery of important vitamins and how to produce them has been so significant to human health that many of those who were integral to the discoveries have been awarded the Nobel Prize in Medicine; more than 10 Nobel Prizes have been divided among almost 20 eminent scientists for the discovery or isolation of vitamins A, B1, B12, C, D, E, and K. Over the second half of the 20th century, after the beginning of widespread supplementation to everyday food items, the incidences of the conditions covered here went down dramatically across much of the world.

Of course, the minerals essential to the human body play similarly important roles in maintaining health. However, humans have not historically had a widespread significant problem acquiring these nutrients, as most plants absorb many minerals from the soil. With the increased processing of our food throughout the 20th century, however, some of these minerals have been lost, and have had to be re-added to the average Western diet through supplementation. In the rest of the world, displacement due to war, and unfortified food from aid programs, has left survivors with enough calories, but not enough nutrients. Supplementation of assistance food and local fortification of salt and flour is beginning to help give displaced people (especially displaced children) a new chance at life without these and other nutritional diseases.

In the developed world, you won’t be the healthiest bloke on the block if you eat nothing but breakfast cereal and cartons of juice—but the food industry has ensured that you at least won’t die of malnutrition. Even people with healthy diets benefit from the supplementation of vitamins and minerals in common foodstuffs, and adding the nutrients costs next to nothing. Doctors and nutritionists still agree that the healthiest way to acquire your necessary vitamins and minerals is by eating a balanced diet and spending time outdoors each day, but in the course of modern life, that’s not always possible, and if people are going to eat poorly either way, we may as well keep them from dropping dead of scurvy!

10 Terrifyingly Huge Birds You Should Know

AndreaWillmore/iStock via Getty Images
AndreaWillmore/iStock via Getty Images

They’re gigantic, they’re often defensive, and you wouldn’t want to run into them in a zoo after hours. Meet a few of the world’s biggest birds with attitude, from flightless giants to modern-day pterodactyls.

1. Ostrich

Everyone knows that the ostrich is the world’s biggest bird, weighing an average of 230 pounds and standing 7 feet tall (and some individuals can grow up to 9 feet). They can also chase you down: Ostriches are the fastest species on two legs, with a top speed of about 43 mph. They can maintain a swift 30 mph pace for 10 miles, making them the marathon champs of the avian world.

2. Southern Cassowary

Often called the most dangerous bird on Earth, in addition to being one of the planet’s biggest birds, the southern cassowary is roughly 150 pounds of mean. On each foot is a 5-inch claw that cassowaries use to defend themselves. At least two people have been kicked to death by cassowaries, the most recent being a Florida man who unwisely kept one of the birds as a pet.

3. Emu

Emu with eggs
JohnCarnemolla/iStock via Getty Images

Like a smaller, shaggier ostrich, the 5- to 6-foot emu is the second-largest bird on Earth (as well as a goofy spokesbird for insurance). During the breeding season, female emus fight enthusiastically over unattached males. But the results of this mating ritual are impressive: clutches of forest-green, oval eggs that resemble giant avocados.

4. Greater Rhea

This flightless bird is named for the Titan goddess Rhea, who gave birth to all of the Olympian gods and goddesses in Greek mythology. At up to 5 feet tall and 66 pounds, the greater rhea may not seem like as much of a terror as the ostrich. But it gathers in massive flocks of up to 100 birds during the non-breeding season, so watch out if you happen to be in its South American habitat.

5. Dalmatian Pelican

Dalmatian pelicans
musicinside/iStock via Getty Images

How scary can a pelican be, you ask? When it stands almost 6 feet tall, weighs 33 pounds, and has a wingspan of 9 feet—all traits of the Dalmatian pelican—it's pretty petrifying. These scruffy-feathered monsters, native to Europe and Asia, breed in colonies of up to 250 pairs and can gulp impressive mouthfuls of fish in one go.

6. Mute Swan

One of the heaviest flying birds, mute swans look harmless as they glide over ponds, lakes, and rivers. But mute swans are far from silent when defending their families and territory. Male swans warn interlopers that they’re getting too close with a hiss, then can launch a straight-up assault, bashing the intruder with their wings. They’ll even attack kayakers, canoeists, and people just minding their own business.

7. Andean Condor

Andean condor
Donyanedomam/iStock via Getty Images

This freakishly big vulture isn’t satisfied with just any carrion—it prefers large carcasses like cattle and deer for dinner. Maintaining its average weight of 25 pounds requires a lot of calories, after all. Its wingspan is slightly less than its northern cousin, the California condor, but it still reaches a dramatic 9 to 10 feet.

8. Cinereous Vulture

Another big bird with a 10-foot wingspan, this Old World vulture has excellent vision to spot carrion while it flies, and a featherless head that resists the accumulation of gore when it feeds. Though it’s intimidating to look at, the cinereous vulture plays an important role in its ecosystem by cleaning up roadkill and other dead animals.

9. Marabou Stork

Marabou stork
Sander Meertins/iStock via Getty Images

As if its red-tinged wattle, black back, and dagger-esque bill weren’t alarming enough, the marabou stork is sometimes called the “undertaker bird” thanks to its Dracula-like appearance. It also eats other birds. The largest verified wingspan on a marabou stork measured 10.5 feet, though unverified reports cited a specimen with 13.3-foot span.

10. Shoebill

Shoebill storks may not be the tallest, heaviest, or widest-winged birds, but just look at that death stare. On top of having a nutcracker for a face, the 5-foot-tall shoebill leads a fearsome lifestyle. It stands absolutely still for hours to hunt prey, watching for lungfish or baby crocodiles, then spreads its wings and collapses over it while trapping the target in its bill.

10 Dramatic Downton Abbey Fan Theories

Jim Carter as Mr. Carson in Downton Abbey (2019).
Jim Carter as Mr. Carson in Downton Abbey (2019).
Focus Features

Despite its exhaustively polished veneer, Downton Abbey was always a soap opera. Julian Fellowes's historical drama about a family of aristocrats and their many servants could never resist a good shocker, and it deployed plenty of them over the course of six seasons. The valet was suspected of murder (twice). One of the Crawley sisters got knocked up by her older married boyfriend, who promptly went missing. And another sister’s first sexual encounter ended in death. Considering all this, it should come as no surprise that fans have developed similarly wacky theories about the show. These fan theories include secret parentage, undercover spies, and, of course, poison.

Brush up on the best of them before the Downton Abbey movie hits theaters—just in case the whole miscarriage curse comes up.

1. Mr. Carson is Lady Mary’s father.

This theory all comes down to eyes. As you may recall from science class, certain genes are dominant and others are recessive. This is perhaps most easily understood through eye color, where brown eye color, a dominant gene, is expressed as BB and blue eye color, a recessive gene, is expressed as bb. A parent with brown eyes might carry the recessive blue eye gene (i.e. Bb), but if you plot out genetic probabilities on a basic Punnett square, two blue-eyed parents with double bbs have seemingly no shot at producing a Bb baby. Now, what does any of this have to do with Downton Abbey? Both Lord and Lady Grantham have blue eyes, but their eldest daughter, Mary, has brown eyes. This has led some fans to speculate that Lady Mary is actually the daughter of Carson, the family’s beloved butler who has always acted as as sort of second father to Mary. As debunkers have noted, two blue-eyed people can have a brown-eyed child, because recessive genes aren’t that simple. But isn’t it wild to think of Carson and Cora having an affair?

2. Thomas Barrow poisoned Kemal Pamuk.

One of the soapiest subplots of Downton Abbey's first season involved “poor Mr. Pamuk,” the dashing Turkish diplomat who makes a fateful visit to the Abbey. After enjoying a day of fox hunting and an evening of sparkling conversation, Kemal Pamuk drops dead ... right in Lady Mary’s bed. The cause, it is later revealed, was a heart attack, but many viewers suspected something more sinister. Earlier in the episode, the Crawleys’ closeted footman, Thomas Barrow, made a pass at Pamuk, which the diplomat rejected quite forcefully—so much so that he threatened to get Thomas fired. That placed the footman in a tricky situation, but it was nothing a little poison couldn't fix, and that’s exactly why some fans believe Thomas slipped something into Mr. Pamuk’s dinner.

3. Lady Grantham’s miscarriage started a curse.

In the Season 1 finale, tragedy strikes. The newly pregnant Lady Grantham slips on a bar of soap, falling onto the bathroom tiles and inducing a miscarriage. It’s a sad moment, but it’s also, Reddit claims, the source of the house’s future misfortune. According to this theory, the miscarriage kicks off a curse of deadly pregnancies: Lady Sybil dies in childbirth; Matthew Crawley dies in a car accident soon after the birth of his son; and when the maid Ethel Parks becomes pregnant with Major Bryant’s child, he dies, too.

4. Mr. Bates is actually a bad guy.

Brendan Coyle and Joanne Froggatt in Downton Abbey (2019).
Brendan Coyle and Joanne Froggatt in Downton Abbey (2019).
Focus Features

Downton Abbey invests a lot of time and effort in convincing us that John Bates, Lord Grantham's trusty, is a great guy—despite his checkered past and multiple murder allegations. But what if everyone’s assumptions about Bates are exactly right? Some Redditors believe Bates is just a remorseless serial killer, pointing to his intense hatred of his first wife and “creepy vibes” as evidence. Anna had better watch out.

5. Michael Gregson is a spy.

Lady Edith’s boss and lover Michael Gregson is the publisher of a London magazine, The Sketch. Thanks to his job, he knows tons of important people, travels all over the world, and speaks multiple languages. He eventually disappears inside Germany in season 4, and later dispatches to the Crawley family imply that he was a victim of Adolf Hitler’s “thugs.” (The show timeline places Gregson in Munich right around the time of the Beer Hall Putsch.) Or at least, that’s the official story. Another one suggests that Gregson was a British spy gathering intel on the insurgent Nazis—and he might not have died at all. His superiors simply needed to feed Edith a lie that would discourage her from poking around, so they made up a cover story that someone who follows the news would believe.

6. Lady Rosamund Painswick is Lady Edith’s mother.

When Lady Edith becomes pregnant with Michael Gregson’s child, she finds a strong support system in her aunt, Lady Rosamund Painswick. Upon learning Edith’s secret, Rosamund travels to Downton Abbey to help her niece through her pregnancy, and suggests adoption options as the due date draws near. Some fans have interpreted this empathy as a clue that Rosamund, not Lady Grantham, is Edith’s true mother. It could also explain why Edith looks (and behaves) so different from her sisters. Or it could just be a sign that Rosamund cares about her niece.

7. Lady Mary’s “operation” was IVF.

In season 3, Lady Mary claims to have undergone a “small operation” that will help her start a family with Matthew. It’s maddeningly unclear what this operation entails, but one wild guess is that she had an early version of IVF. The complete crackpot theory is that this was a cover for Matthew’s infertility, which the doctors wouldn’t disclose to him, presumably to preserve his 1920s masculinity.

8. Lady Mary’s son George becomes a Royal Air Force pilot in World War II.

Lady Mary’s son George is only five years old in the series finale of Downton Abbey. But that means he would theoretically be 18 in the fall of 1939, which is exactly when World War II broke out in Europe. He would almost certainly enlist, as show creator Julian Fellowes himself has suggested. But Decider has more specifically theorized that George would join the Royal Air Force (RAF), “with a desire to rebel against his emotionally distant mother and find purpose in a greater cause.” Sounds like George would be taking part in some dangerous missions, putting the entire family’s future at risk.

9. Public tours keep the estate alive.

The Crawleys spend much of Downton Abbey fretting about the future management of their estate—partially because Lord Grantham is kind of bad at it. But Lady Mary has taken over when the series ends, and Fellowes believes she’d find savvy ways to keep her family’s home in their hands. “She would probably have opened the house to the public in the 1960s, as so many of them did,” Fellowes told Deadline. “And she’d have retreated to a wing, and maybe only occupied the whole house during the winters. My own belief is that the Crawleys would still be there.”

10. The Dowager Countess keeps Denker and Spratt around for the drama.

Gladys Denker is a maid to the Dowager Countess. Septimus Spratt is her butler. These two do not like each other, and they’re quite public about it. Denker and Spratt’s unprofessional squabbles would’ve gotten plenty of other servants fired, but fans believe the Dowager Countess keeps them employed for her own amusement.

SECTIONS

arrow
LIVE SMARTER