4 Diseases Caused by a Lack of Essential Vitamins and Minerals

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iStock

Companies pushing products with added vitamins and minerals can fool people into thinking that they’re eating a “healthy” food when they’re not—but it’s not like those vitamins and minerals are there for no reason. For much of human history, diseases of nutrient deficiency were the norm, and in some parts of the world, they still persist. Even into the 20th century, conditions caused by a lack of certain vitamins or minerals were endemic to North America and Europe. Artificially added nutrients may not make a food “healthy,” but they do stave off several debilitating, and sometimes fatal, diseases of malnutrition. Here are a few of those maladies.

1. Scurvy

The disease of pirates: the grey-death. Scurvy is caused by a lack of vitamin C, whose chemical name, ascorbic acid, is derived from the Latin term for scurvy, scorbutus. Even though the disease was known since ancient times (described by Hippocrates around 400 BCE), it was not a scourge to those who were largely land-bound. Even though its causes were unknown, many cultures realized that eating certain herbs could reverse the symptoms, and as long as there was access to fresh food, it was generally kept under control.

Scurvy didn’t become a significant problem until the Age of Discovery (beginning in the 15th century), when people at sea were not able to access that much-needed fresh food for months at a time. Preserved meats and carbohydrates contained no vitamin C, and unlike most animals, the human body is not able to create vitamin C on its own.

The early symptoms of scurvy include spongy gums, pain in the joints, and blood spots appearing under the skin. As the disease progressed, the teeth would become loose, extreme halitosis (bad breath) would develop, the afflicted would become too weak to walk or work, be in too much pain to eat, and would die “mid-sentence,” often from a burst blood vessel. Many of the early explorers lost great numbers of men to scurvy: Vasco de Gama lost 116 out of 170 men in 1499, and in 1520, Magellan lost 208 out of 230. A few deaths were attributable to other causes, but the vast majority were due to scurvy.

Despite not being able to pinpoint the exact cause of scurvy, in the 18th century, naval physician James Lind was able to prove, in what’s considered to be the first controlled scientific experiment, that scurvy could be prevented (and cured) by incorporating citrus fruits such as limes and oranges into the diet of sailors. Although his findings weren’t widely accepted at first, the British Navy eventually began issuing standard rations of lemon juice, and later, limes, to their sailors—which gave rise to the term “limey” in reference to the British.

These days, scurvy is an extremely rare condition, almost exclusively caused by someone eating a completely unvaried diet. In most cases, high levels of oral supplementation of vitamin C are enough to reverse the condition in a matter of weeks, and death by scurvy is almost unheard of.

2. Rickets

This condition is brought on by a lack of vitamin D, which causes the body to be unable to absorb or deposit calcium. Less commonly, it can also be caused by a lack of calcium or phosphorus, but vitamin D deficiency is by far the most common cause. Unlike vitamin C, the human body is able to produce vitamin D, but only if it has the metabolic precursors available to it.

When the skin is exposed to ultraviolet light (such as from the sun), cholesterol in the skin reacts and forms cholecalciferol, which is then processed in the liver and kidneys to create the active form of vitamin D. Even with a nominally healthy diet, without enough sun exposure, the body can’t produce the vitamin D precursors on its own. This is actually re-emerging as a health concern among some increasingly-indoor groups of people, and is one of the few hypovitaminosis (lack of vitamin) conditions not considered to be a “disease of the past.” Luckily, when the deficiency is recognized, cholecalciferol can be directly taken as a vitamin supplement or acquired from eating organ meats and oils, such as cod liver oil, allowing the body to resume producing vitamin D.

Rickets is a condition of children, as the deficiency’s most severe effects are on developing bones; in adults, “bone-softening,” or osteomalacia, can be caused by the same vitamin deficiency. But in adults, it both takes significantly longer to develop and tends to cause tip-off signs that something is wrong before bone warping sets in, such as extreme pain in the bones, and unexplained muscle weakness. In children, especially those that don’t or can’t receive regular check-ups, deformity and debilitation by the deficiency is often only noticed after significant damage has been done to their developing skeletons.

The most telling symptoms of rickets are at the epiphyses (growth plates) of bones: The body is unable to lengthen bones by depositing calcium, and ends up with bones that flare outward in a “cupping” appearance. This leads to costochondral swelling, or what’s known as the “rachitic rosary” along the ribcage of the child, as well as widened wrists and “thick” joints. Before widened wrists or rachitic rosary appears, the softening of the skull bones can lead to “Caput Quadratum”—a square-headed appearance, and often the first sign of skeletal growth problems. If left untreated, rickets also can cause an extremely curved back, stunted growth, and frequent fractures—all of which can lead to permanent and debilitating deformity.

3. Beriberi

This condition is largely confined to Asia, especially in countries where boiled rice is a staple. The Sinhalese term “beri-beri” means, “I cannot, I cannot,” and derives from the inability to perform even the simplest of tasks once the polyneuritis (nerve inflammation) caused by the deficiency of vitamin B1 (thiamine) has permanently damaged the neurons, when the condition has progressed to the end-stage.

Although beriberi was known to exist in rice-eating countries several centuries back, its prevalence boomed with the introduction of steam-driven rice-polishing mills from Europe. The superior taste of the milled white rice led many locals to abandon the local (unpolished) brown rice, and in doing so, abandon their primary source of thiamine. From the 1860s to the turn of the 20th century, people whose plant consumption was limited to the polished white rice would often come down with weakness, pain, weight loss, difficulty walking, and emotional disturbances. Beriberi became one of the leading causes of mortality in the region.

In the 1880s, a doctor named Christiaan Eijkman began researching the causes of this epidemic at a laboratory in the Dutch East Indies (now Jakarta, Indonesia), and initially believed that the condition was caused by a bacterial infection. However, after years of study, he came to the conclusion that “white rice is poisonous.” He discovered this by feeding a group of chickens solely white rice, and another group unpolished brown rice. The chickens that ate the white rice came down with beriberi-like symptoms, while the others stayed healthy. Eijkman also discovered that when the chickens fed white rice were subsequently fed brown rice, they recovered from their illness! Later dietary testing on prisoners confirmed his results. Even though he didn’t know the cause of the condition, Eijkman proved that white rice was the culprit, and shared the 1929 Nobel Prize in Medicine for his discovery.

Beriberi is occasionally seen in the modern world, but its primary cause is chronic alcoholism—the poor diets of some chronic alcoholics, combined with the decreased absorption of what thiamine is consumed, leads to symptoms that unfortunately are sometimes left undiagnosed until it’s too late. Recently, beriberi was also seen in Haitian prisons when the prison system began buying imported polished rice from the United States, and stopped feeding their inmates the local brown rice.

4. Pellagra

What causes blistering of the skin in the sun, pale skin, a craving for raw meat, blood dripping from the mouth, aggression, and insanity? If you answered “vampirism,” you’re close—the myth of the vampire may have its roots in the condition known as “pellagra.”

Pellagra is caused by a lack of vitamin B3 (niacin). First identified and commonly diagnosed in the Asturian Empire (now Northern Spain), it was originally called “Asturian leprosy.” However, the condition was seen throughout Europe, the Middle East, and North Africa, wherever a large percentage of food energy was derived from corn, and fresh meat was not available. The area of highest prevalence was Northern Italy, where Francesco Frapoli of Milan called it “pelle agra,” meaning “sour skin.”

It was initially believed that either the corn itself, or some insect associated with corn, was causing pellagra. This belief was reinforced when much of France eliminated corn as a food staple and virtually eradicated the condition. Between the era that corn was introduced to Europe (the early 16th century) and the late 19th century, pellagra was found almost everywhere that poor people subsisted on cornmeal and little else.

Around the turn of the 20th century, people began to notice that despite subsisting on just as much corn as poor Europeans, poor Mesoamerican natives didn’t come down with the condition. It was eventually discovered that this was because the traditional processing of corn in the Americas involved “nixtamalization,” in which the kernels were soaked in limewater before hulling them. The alkali solution freed up the niacin that was present in the grain, but previously inaccessible.

Despite the extensive work of Dr. Joseph Goldberger in the 1910s and 1920s, which proved that pellagra wasn’t caused by a germ but by a dietary deficiency, the condition was occurring in epidemic proportions in the rural Southern US until the 1940s.

Today, pellagra is most common in the poorest regions of the world, especially places that rely upon food aid programs. Some countries still ship unfortified cornmeal rather than corn masa (nixtamalized corn) or fortified cornmeal to developing countries or to their own impoverished populations. China, parts of Africa, Indonesia, and North Korea all have endemic pellagra among their lowest classes.

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The discovery of important vitamins and how to produce them has been so significant to human health that many of those who were integral to the discoveries have been awarded the Nobel Prize in Medicine; more than 10 Nobel Prizes have been divided among almost 20 eminent scientists for the discovery or isolation of vitamins A, B1, B12, C, D, E, and K. Over the second half of the 20th century, after the beginning of widespread supplementation to everyday food items, the incidences of the conditions covered here went down dramatically across much of the world.

Of course, the minerals essential to the human body play similarly important roles in maintaining health. However, humans have not historically had a widespread significant problem acquiring these nutrients, as most plants absorb many minerals from the soil. With the increased processing of our food throughout the 20th century, however, some of these minerals have been lost, and have had to be re-added to the average Western diet through supplementation. In the rest of the world, displacement due to war, and unfortified food from aid programs, has left survivors with enough calories, but not enough nutrients. Supplementation of assistance food and local fortification of salt and flour is beginning to help give displaced people (especially displaced children) a new chance at life without these and other nutritional diseases.

In the developed world, you won’t be the healthiest bloke on the block if you eat nothing but breakfast cereal and cartons of juice—but the food industry has ensured that you at least won’t die of malnutrition. Even people with healthy diets benefit from the supplementation of vitamins and minerals in common foodstuffs, and adding the nutrients costs next to nothing. Doctors and nutritionists still agree that the healthiest way to acquire your necessary vitamins and minerals is by eating a balanced diet and spending time outdoors each day, but in the course of modern life, that’s not always possible, and if people are going to eat poorly either way, we may as well keep them from dropping dead of scurvy!

11 Facts About French Bulldogs

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iStock/carolinemaryan

These cute little dogs are enjoying a serious comeback. Here’s the scoop on the fourth most popular dog breed in America. 

1. FRENCH BULLDOGS HAVE ROOTS IN ENGLAND.


iStock/malrok

The French bulldog’s origins are murky, but most sources trace their roots to English bulldogs. Lace makers in England were drawn to the toy version of the dog and would use the smaller pups as lap warmers while they worked. When the lace industry moved to France, they took their dogs with them. There, the English bulldogs probably bred with terriers to create bouledogues français, or French bulldogs. 

2. THEY WERE BRED TO BE GREAT COMPANIONS.

Frenchies are affectionate, friendly dogs that were bred to be companions. Although they’re somewhat slow to be housebroken, they get along well with other dogs and aren’t big barkers. The dogs don’t need much exercise, so they are fine in small areas and enjoy the safety of a crate.

3. THEY CAN'T SWIM.


iStock/ginastancel

As a result of their squat frame and bulbous head, French bulldogs can’t swim, so pool owners should keep a watchful eye on their pups. Keep in mind that if you plan a beach vacation, your furry friend might feel a little left out. 

4. FLYING IS A PROBLEM FOR THEM, TOO.

French Bulldogs are a brachycephalic breed, meaning they have shorter snouts than other dogs. These pushed-in faces can lead to a variety of breathing problems. This facial structure, coupled with high stress and uncomfortably warm temperatures, can lead to fatal situations for dogs with smaller snouts. Many breeds like bulldogs and pugs have perished while flying, so as a result, many airlines have banned them. 

Luckily there are special airlines just for pets, like Pet Jets. These companies will transport dogs with special needs on their own flights separate from their owners. There's a human on board to take care of any pups that get sick or panic. 

5. THEY MAKE GREAT BABYSITTERS.

When a baby orangutan named Malone was abandoned by his mother, the Twycross Zoo in England didn’t know if he would make it. Luckily, a 9-year-old French bulldog named Bugsy stepped in and took care of the little guy. The pair became fast friends and would even fall asleep together. When Malone was big enough, he joined the other orangutans at the zoo. 

6. THEY'RE SENSITIVE TO CRITICISM.

Frenchies are very sensitive, so they do not take criticism lightly. If you scold a French bulldog, it might take it very seriously and mope around the house. French bulldogs respond better to positive reinforcement and encouragement. 

7. THEY'RE A TALKATIVE BREED. 

French bulldogs might not bark much, but they do like to “talk.” Using a complex system of yawns, yips, and gargles, the dogs can convey the illusion of their own language. Sometimes they will even sing along with you in the car. 

8. THEY HAVE TWO STYLES OF EARS. 


iStock/IvonneW

Originally, French bulldogs had rose-shaped ears, similar to their larger relative, the English bulldog. English breeders much preferred the shape, but American breeders liked the unique bat ears. When a rose-eared bulldog was featured at the Westminster Kennel Club in 1897, American dog fanciers were very angry

9. THIS CONTROVERSY LED TO THE FORMATION OF THE FRENCH BULL DOG CLUB OF AMERICA.

The FBDCA was founded in protest of the rose-shaped ears. The organization threw its first specialty show in 1898 at New York City’s famed Waldorf-Astoria. The FBDCA website described the event: “amid palms, potted plants, rich rugs and soft divans. Hundreds of engraved invitations were sent out and the cream of New York society showed up. And, of course, rose-eared dogs were not welcomed.”

The somewhat catty efforts of the club led to the breed moving away from rose-shaped ears entirely. Today, French bulldogs feature the bat-shaped ears American breeders fought to showcase. 

10. MOST FRENCH BULLDOGS ARE BORN THROUGH ARTIFICIAL INSEMINATION. 

Due to their unusual proportions, the dogs have a little trouble copulating. Males have a hard time reaching the females, and they often get overheated and exhausted when trying to get things going. As a result, a large majority of French bulldogs are created through artificial insemination. While this measure makes each litter of pups more expensive, it also allows breeders to check for potential problems during the process. 

French bulldogs often also have problems giving birth, so many must undergo a C-section. The operation ensures the dog will not have to weather too much stress and prevents future health complications.

11. CELEBRITIES LOVE FRENCHIES.

Frenchies make plenty of appearances in the tabloids. Celebrities like Lady Gaga, Hugh Jackman, and The Rock have all been seen frolicking with their French bulldogs. Even Leonardo DiCaprio has one—aptly named Django. Hugh Jackman’s Frenchie is named Dali, after the way the dog’s mouth curls like the famous artist’s mustache. 

This article originally ran in 2015.

12 Festive Facts About A Christmas Story

Warner Home Video
Warner Home Video

Which Oscar-winning star wanted to play Ralphie Parker's dad? Which actor went on to have a seedy career in the adult film industry? Can you really get your tongue stuck to a metal pole? On the 35th anniversary of A Christmas Story's debut, here are a few tidbits about the holiday classic to tide you over until TNT's 24-hour Christmas marathon.

1. JACK NICHOLSON WAS INTERESTED IN PLAYING RALPHIE'S DAD.

Though Jack Nicholson was reportedly offered the role of The Old Man Parker, and interested, casting—and paying—him would have meant doubling the budget. But director Bob Clark, who didn't know Nicholson was interested, said Darren McGavin was the perfect choice for the role.

2. IT OWES A DEBT TO PORKY'S.

What does Porky's—a raunchy 1980s teen sex comedy—have to do with a wholesome film like A Christmas Story? Bob Clark directed both: Porky's in 1982 and A Christmas Story in 1983. If Porky's hadn't given him the professional and financial success he needed, he wouldn't have been able to bring A Christmas Story to the big screen.

3. RALPHIE SAYS HE WANTS A RED RYDER BB GUN A LOT.

For anyone keeping count, Ralphie says he wants the Red Ryder BB Gun 28 times throughout the course of the movie. That's approximately once every three minutes and 20 seconds.

4. THESE DAYS, PETER BILLINGSLEY SPENDS HIS TIME BEHIND THE CAMERA.

Peter Billingsley, a.k.a. Ralphie, has been good friends with Vince Vaughn since they both appeared in a CBS Schoolbreak Special together in the early 1990s. He doesn't do much acting these days, though he has popped up in cameos (including one in Elf, another holiday classic). Instead, Billingsley prefers to spend his time behind the camera as a director and producer. He has done a lot of work with Vaughn and Jon Favreau, including serving as an executive producer on Iron Man (in which he also made a cameo).

5. YES, YOU CAN GET YOUR TONGUE STUCK ON A PIECE OF COLD METAL.

Mythbusters tested whether it was possible to get your tongue truly stuck on a piece of cold metal. Guess what? It is. So don't triple dog dare your best friend to try it.

6. ONE OF THE YOUNG ACTORS MOVED ON TO A CAREER IN ADULT FILMS.

Scott Schwartz, who played Flick (the kid who stuck his tongue to the frozen flagpole), spent several years working in the adult film industry. In 2000, he turned his attention back to mainstream films. His most recent role was as "Disco City Hot Dog Vendor" in the 2017 TV movie Vape Warz.

7. RALPHIE'S HOUSE IS NOW A MUSEUM.

Next time you're in Cleveland, you can visit the original house from the movie. It was sold on eBay in 2004 for $150,000. Collector Brian Jones bought the house and restored it to its movie glory and stocked it up with some of the original props from the film, including Randy's snowsuit.

8. THE IDEA FOR THE FILM CAME TO BOB CLARK WHILE HE WAS DRIVING TO PICK UP A DATE.

Peter Billingsley, Melinda Dillon, Darren McGavin, and Ian Petrella in A Christmas Story (1983)
Warner Home Video

Director Bob Clark got the idea for the movie when he was driving to pick up a date. He heard Jean Shepherd on the radio doing a reading of his short story collection, In God We Trust, All Others Pay Cash, which included some bits that eventually ended up in A Christmas Story. Clark said he drove around the block for an hour until the program ended (which his date was not too happy about).

9. IT PARTLY INSPIRED THE WONDER YEARS.

The Wonder Years was inspired in part by A Christmas Story. In fact, toward the very end of the series, Peter Billingsley even played one of Kevin Arnold's roommates.

10. YOU CAN STILL BUY A RED RYDER BB GUN.

The real Red Ryder BB Gun was first made in 1938 and was named after a comic strip cowboy. You can still buy it today for the low, low price of $39.99. But the original wasn't quite the same as the one in the movie; it lacked the compass and sundial that both the Jean Shepherd story and the movie call for. Special versions had to be made just for A Christmas Story.

11. THE LEG LAMP CAN ALSO BE YOURS.

Peter Billingsley and Melinda Dillon in A Christmas Story (1983)
Warner Home Video

While we're talking shopping: you know you want the leg lamp. Put it in your window! Be the envy of your neighbors! It's a Major Award! You can buy it on Amazon (there's a 40-inch version, as well as a 20-inch replica). If you're not feeling quite so flamboyant, they also make a nightlight version.

12. IT SPAWNED A TRIO OF SEQUELS.

A Christmas Story led to two little-talked-about sequels. The first one was a 1988 made-for-TV movie, Ollie Hopnoodle's Haven of Bliss. Jerry O'Connell played 14-year-old Ralphie, who is excited about his first job—as a furniture mover. Of course, it ends up being awful, and it might make him miss the annual family vacation at Mr. Hopnoodle's lakeside cabins.

My Summer Story, a.k.a. It Runs in the Family, debuted on the big screen in 1994. Kieran Culkin plays Ralphie, Mary Steenburgen is his mom, and Charles Grodin is his dad.

And in 2012, the direct-to-video sequel A Christmas Story 2 picked up five years after the original movie left off, with Ralphie attempting to get his parents to buy him a car.

An earlier version of this story appeared in 2008.

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