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6 Ways Technology Can Help Mental Health Disorders

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Today is World Mental Health Day. Mental health issues affect hundreds of millions of people around the globe; according to the World Health Organization, some 300 million suffer from depression, and another 260 million grapple with anxiety disorders. While researchers haven't developed any breakthrough mental health drugs in nearly three decades, new technological innovations are helping some patients connect with a therapist, get diagnosed, track moods, manage or mitigate symptoms, and stick to treatments. Here are just a sampling of them.

1. APPS FOR EVERYTHING FROM PTSD TO ADDICTION

The "there's an app for that" slogan is now true for the complex world of mental health care. There are thousands. Some apps are targeted at users with specific conditions, such as anxiety, schizophrenia, or depression, and are designed to assuage and manage symptoms, track moods and thoughts, or help individuals stick with treatments. Others are aimed at improving memory, coping, and thinking skills, or managing stress through meditation or mindfulness. There are also apps for post-traumatic stress disorder (PTSD), eating disorders, and addiction. The list goes on.

Mental health apps have plenty of benefits, including convenience, anonymity, and a low price. But experts caution prospective users against using them as a stand-in for professional treatment, according to the National Institute of Mental Health (NIMH). Most aren't backed by peer-reviewed research or clinical trials, partially because tech development moves faster than traditional scientific testing. Confidentiality is also a major issue, as many of these apps don't adhere to standard healthcare privacy guidelines.

Yet some preliminary studies have shown that they can yield patient improvements. Vet any app you're considering with a doctor or therapist, focusing on ones that rely on evidence-based treatment such as cognitive behavior therapy. Double-check the app developer's credentials before downloading: The most trustworthy are typically affiliated with academic research institutions or government agencies, according to the American Psychological Association. And choose one with an intuitive interface; it will be easier to stick with, so you might see better outcomes.

To learn more about the pros and cons, visit the NIMH's comprehensive report on the subject.

2. ONE-ON-ONE THERAPY THROUGH VIDEO AND TEXT

With a shortage of mental health professionals in the U.S., online or mobile therapy appears to be a good solution for prospective patients who can't find an available one in their area. It's also promising for those who simply don't have the time or resources for in-person appointments, or are afraid of stigma.

Some services or platforms allow users to connect with therapists via voice or video on a computer or phone. Others are text-based and allow patients to send unlimited messages via their phones, 24/7, for a flat monthly fee.

3. BEHAVIOR TRACKERS THAT MAY INDICATE AN IMPENDING MENTAL HEALTH CRISIS

While some mental health apps are designed to deliver outcomes (an improved mood, lessened anxiety), researchers are also working to harness mobile technology to detect suicidal inclinations, burgeoning manic episodes, or depressive episodes before they manifest.

One such scientist is Dr. Thomas Insel, a psychiatrist and former head of the NIMH. After a stint with Verily, the life sciences unit of Alphabet (the parent company of Google), Insel left the tech giant to co-found a start-up called Mindstrong. Both organizations, he told CNBC, are working on apps that monitor users' smartphone behavior—with permission from the user.

For example, if a user starts typing more rapidly than normal, their syntax changes, or they indulge in impulsive shopping sprees, that might be an indicator that they're manic. If they don't respond to texts from family and friends, they might be depressed. Together, this data collection could create what Insel calls a "digital phenotype," which could be described as a personalized mental health map. This could help users or their loved ones mitigate any potential crises through preventative treatment.

This line of research is promising, but Insel noted that it's still unclear whether the approach will yield long-term outcomes for patients—or if the tech itself is fine-tuned enough to observe behavior changes.

4. SMART SOFTWARE THAT FINDS AT-RISK PATIENTS IN MEDICAL RECORDS

Some insurance companies are now using cloud-based software platforms to review electronic medical records and insurance claims data to identify patients at risk for developing mental health conditions like depression. Then, they connect them with appropriate treatments through a network of behavioral health specialists.

5. VIRTUAL-REALITY TREATMENTS

In addition to treating PTSD with medication, therapy, and exercise, some physicians use a technique called exposure therapy, which is designed to help patients relive trauma-related phenomena in a controlled, safe environment, such as a doctor's office. This helps patients get habituated to the memories so they no longer trigger flashbacks and anxiety. Scientists have tested VR as a tool for exposure therapy in clinical trials, and a handful of clinicians around the U.S. are now trained to use it in their practices.

Headsets whisk patients back in time using a combination of images and sounds. While wearing the headsets, subjects discuss past experiences with therapists until they become desensitized to the triggers before them.

Meanwhile, researchers like Yale scientist Sarah Fineberg are using computer games and VR to understand feelings of social rejection in people with borderline personality disorder (BPD), a complicated condition in which sufferers have a hard time regulating emotions, have a distorted sense of self, and are prone to extreme mood swings, especially towards the people in their lives. 

6. A GOOGLE SCREENING THAT LETS YOU KNOW IF YOU'RE DEPRESSED

Google recently teamed up with the National Alliance on Mental Illness (NAMI), a nationwide grassroots mental health advocacy group, to offer a mental health screening questionnaire to U.S. residents who search for "depression" on their mobile phones. The top result is a box called a "knowledge panel," which has information on depression, its symptoms, and potential treatments. To get screened, click the option "Check if you're clinically depressed" to take a confidential, medically backed self-assessment quiz.

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New Cancer-Fighting Nanobots Can Track Down Tumors and Cut Off Their Blood Supply
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Scientists have developed a new way to cut off the blood flow to cancerous tumors, causing them to eventually shrivel up and die. As Business Insider reports, the new treatment uses a design inspired by origami to infiltrate crucial blood vessels while leaving the rest of the body unharmed.

A team of molecular chemists from Arizona State University and the Chinese Academy of Sciences describe their method in the journal Nature Biotechnology. First, they constructed robots that are 1000 times smaller than a human hair from strands of DNA. These tiny devices contain enzymes called thrombin that encourage blood clotting, and they're rolled up tightly enough to keep the substance contained.

Next, researchers injected the robots into the bloodstreams of mice and small pigs sick with different types of cancer. The DNA sought the tumor in the body while leaving healthy cells alone. The robot knew when it reached the tumor and responded by unfurling and releasing the thrombin into the blood vessel that fed it. A clot started to form, eventually blocking off the tumor's blood supply and causing the cancerous tissues to die.

The treatment has been tested on dozen of animals with breast, lung, skin, and ovarian cancers. In mice, the average life expectancy doubled, and in three of the skin cancer cases tumors regressed completely.

Researchers are optimistic about the therapy's effectiveness on cancers throughout the body. There's not much variation between the blood vessels that supply tumors, whether they're in an ovary in or a prostate. So if triggering a blood clot causes one type of tumor to waste away, the same method holds promise for other cancers.

But before the scientists think too far ahead, they'll need to test the treatments on human patients. Nanobots have been an appealing cancer-fighting option to researchers for years. If effective, the machines can target cancer at the microscopic level without causing harm to healthy cells. But if something goes wrong, the bots could end up attacking the wrong tissue and leave the patient worse off. Study co-author Hao Yan believes this latest method may be the one that gets it right. He said in a statement, "I think we are much closer to real, practical medical applications of the technology."

[h/t Business Insider]

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New Peanut Allergy Patch Could Be Coming to Pharmacies This Year
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About 6 million people in the U.S. and Europe have severe peanut allergies, including more than 2 million children. Now, French biotechnology company DBV Technologies SA has secured an FDA review for its peanut allergy patch, Bloomberg reports.

If approved, the company aims to start selling the Viaskin patch to children afflicted with peanut allergies in the second half of 2018. The FDA's decision comes in spite of the patch's disappointing study results last year, which found the product to be less effective than DBV hoped (though it did receive high marks for safety). The FDA has also granted Viaskin breakthrough-therapy and fast-track designations, which means a faster review process.

DBV's potentially life-saving product is a small disc that is placed on the arm or between the shoulder blades. It works like a vaccine, exposing the wearer's immune system to micro-doses of peanut protein to increase tolerance. It's intended to reduce the chances of having a severe allergic reaction to accidental exposure.

The patch might have competition: Aimmune Therapeutics Inc., which specializes in food allergy treatments, and the drug company Regeneron Pharmaceuticals Inc. are working together to develop a cure for peanut allergies.

[h/t Bloomberg]

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