Why Do We Tan?

iStock / bymuratdeniz
iStock / bymuratdeniz

Sit out in the sun too long and ultraviolet radiation from sunlight penetrates your skin and cells, damaging their RNA and DNA. This is bad news, as DNA provides our bodies with all the genetic instructions they need to develop, survive and go about their business, and this kind of DNA damage can lead to skin cancer. To protect you from this, your body helpfully tans, darkening the the skin with a pigment called melanin that reduces UV penetration into cells.

UV radiation stimulates the darkening of existing melanin and spurs increased melanogenesis, the production of new melanin. Cells called melanocytes generate the pigment and push it out of the cell, where it darkens the skin and absorbs and transforms absorbed UV energy into heat.

Melanogenesis results in a delayed tan that only becomes visible several hours after UV exposure and lasts longer than the tanning caused by darkening of existing melanin. Over time, a tan fades as darkened skin layers are pushed upward by new cells with less melanin, and are eventually scaled off.

Why do we get sunburn?

While we might say someone with sunburn was out “baking” too long or got “fried,” sunburns are different from the burn one might get from, say, touching a hot stove. That’s a thermal burn caused by the heat of the stove. While the sun does give off heat, a sunburn is caused by ultraviolet-B radiation.

When someone’s exposure to UV radiation exceeds their body’s ability to protect the skin with tanning, the radiation  causes damage to DNA, like we talked about above. This prompts the body to try and fix things. Bloodflow to the capillary bed of the dermis (the second outermost layer of skin) increases so cells can repair the damage, which results in warmth and redness of the skin. Inflammatory immune cells also flock to the damaged tissue, causing us to perceive pain and, hopefully, consider staying out of the sun for a while. Eventually, the damaged skin cells die, and the burned skin starts to peel.

What Is the Shelf Life of Donated Eyes?

iStock.com/Pedro_Turrini
iStock.com/Pedro_Turrini

Zoe-Anne Barcellos:

I can only answer for cornea and eye donation.

The FDA does all oversight (no pun intended) of organ disposition.

The main organs—heart, liver, pancreas, lungs, etc.—are transplanted within hours. They are just not viable if they are not being perfused constantly.

The other tissues—like bone, skin, tendons, etc.—do not need to be transplanted immediately. But I am not sure on the regulations of when they need to be transplanted.

With the eyes, there are four tissues that can be recovered.

We recover whole eyes for research and education purposes. These usually go much faster, but we can hold them up to a year.

Conjunctiva can also be recovered; conjunctiva is a clear covering over most of the eye (it is what gets irritated when you have pink eye). I have been working as a recovery tech for five years, and our office has not had a request for "conj" in all that time. I believe it is mostly used for research, but I could be wrong.

Sclera is the white area of your eye. It is fairly thick and flexible. If you have ever touched a reptile egg, that is what it reminds me of. We recover sclera for transplant. They use it for several things, but mainly to patch punctures. Similar to if you pop the inner tube of your bike and repair it. Sclera can also be used to repair ear drums. We can hold on to this for up to a year.

The main thing we recover is corneas. In the U.S., we must transplant these within seven days of recovery. (Recovery is usually within hours of death, but we can push it up to 20 hours after if needed.) Sometimes we have more corneas than we need, and then they are shipped overseas and transplanted up to 14 days after recovery. There is no real different outcome with the later transplant time, but the FDA in the U.S. made the rules. (You can sign up to be an organ, tissue, and eye donor here.)

This post originally appeared on Quora. Click here to view.

Why Are There No Snakes in Ireland?

iStock
iStock

Legend tells of St. Patrick using the power of his faith to drive all of Ireland’s snakes into the sea. It’s an impressive image, but there’s no way it could have happened.

There never were any snakes in Ireland, partly for the same reason that there are no snakes in Hawaii, Iceland, New Zealand, Greenland, or Antarctica: the Emerald Isle is, well, an island.

Eightofnine via Wikimedia Commons // Public Domain

Once upon a time, Ireland was connected to a larger landmass. But that time was an ice age that kept the land far too chilly for cold-blooded reptiles. As the ice age ended around 10,000 years ago, glaciers melted, pouring even more cold water into the now-impassable expanse between Ireland and its neighbors.

Other animals, like wild boars, lynx, and brown bears, managed to make it across—as did a single reptile: the common lizard. Snakes, however, missed their chance.

The country’s serpent-free reputation has, somewhat perversely, turned snake ownership into a status symbol. There have been numerous reports of large pet snakes escaping or being released. As of yet, no species has managed to take hold in the wild—a small miracle in itself.

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