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Scientists Remove the Gluten Genes From Wheat

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Oprah loves bread. We all love bread. But, as gluten-free diets become more mainstream, more and more people are realizing that even if they don't have celiac disease, they still suffer from gluten sensitivity (known as non-celiac gluten sensitivity). And that means no bread. (Or hundreds of other delicious foodstuffs, like beer, or pasta, or fried chicken, or even soy sauce.)

But, in what could be a huge boon for people with gluten issues, scientists in Spain have managed to remove the majority of the proteins that make gluten so troublesome from wheat, according to Digital Trends.

The study, published in the journal Plant Biotechnology, used CRISPR/Cas9 gene-editing technology to drastically reduce the amount of gliadins—a protein in gluten that's particularly problematic for celiacs—in wheat. This technique could allow researchers to breed wheat strains that people with gluten-sensitivity are naturally less reactive to, leading to a naturally low-gluten flour.

Unfortunately, the technique probably won't help people with celiac disease just yet. The researchers were able to eliminate 35 of the 45 gliadin genes in wheat, but that's not enough to make wheat safe for celiacs. The genetic changes reduced reactivity to the gluten in the wheat by 85 percent, which means celiacs would still have an immune response to it.

But for people with less serious gluten-sensitivity issues who can still digest small amounts of gluten, the innovation would allow them to eat wheat products without the resulting stomach hell. And while the technology isn't there just yet, it's possible that celiac-safe wheat could be in our future. The researchers are still working on removing those 10 remaining gliadin genes, which would allow them to create gluten-safe wheat strains. Sadly, no amount of gluten-removing technology will help the poor souls with non-gluten wheat sensitivity.

[h/t Digital Trends]

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'Lime Disease' Could Give You a Nasty Rash This Summer
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A cold Corona or virgin margarita is best enjoyed by the pool, but watch where you’re squeezing those limes. As Slate illustrates in a new video, there’s a lesser-known “lime disease,” and it can give you a nasty skin rash if you’re not careful.

When lime juice comes into contact with your skin and is then exposed to UV rays, it can cause a chemical reaction that results in phytophotodermatitis. It looks a little like a poison ivy reaction or sun poisoning, and some of the symptoms include redness, blistering, and inflammation. It’s the same reaction caused by a corrosive sap on the giant hogweed, an invasive weed that’s spreading throughout the U.S.

"Lime disease" may sound random, but it’s a lot more common than you might think. Dermatologist Barry D. Goldman tells Slate he sees cases of the skin condition almost daily in the summer. Some people have even reported receiving second-degree burns as a result of the citric acid from lime juice. According to the Mayo Clinic, the chemical that causes phytophotodermatitis can also be found in wild parsnip, wild dill, wild parsley, buttercups, and other citrus fruits.

To play it safe, keep your limes confined to the great indoors or wash your hands with soap after handling the fruit. You can learn more about phytophotodermatitis by checking out Slate’s video below.

[h/t Slate]

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Lia
Lia Is a Disposable Pregnancy Test You Can Flush Down the Toilet
Lia
Lia

It’s a common Hollywood plot point: A character spots a discarded pregnancy test in a bathroom trash can. Surprise! Someone’s pregnancy is revealed, though they weren’t yet ready to tell anyone (and perhaps never planned on telling them at all). Lia is a new type of disposable pregnancy test designed to be flushed down the toilet to make sure no one ever experiences that kind of privacy violation, according to Glamour.

Lia hasn’t hit the market yet, but when it does, it will be the first major redesign of the home pregnancy test in decades. The first at-home pregnancy test in the U.S. debuted in 1977, and while it took two hours to show a result, it gave women the option to learn their pregnancy status with relative accuracy (it was 97 percent accurate for positive results, but only 80 percent accurate for negative results) for the first time without going to the doctor. In 1988, Unilever came out with the first wand-style pregnancy test—the plastic kind you pee on to reveal the blue stripe indicators. Since then, not much has changed about the basic design of the at-home pregnancy test except the graphics that companies use to convey the test’s results. (The science undergirding the tests has advanced over the years, though.)

Unlike the plastic sticks, Lia is disposable and can be flushed down the toilet or composted. With the shape reminiscent of a sanitary pad, it works similar to the traditional pee-stick test: You urinate on it, then wait for the stripes to appear. While it’s water-resistant enough to withstand the two minutes of pee-soaking required to get a result, the test strip is made of the type of plant fibers that go into toilet paper and will eventually disintegrate in water. It can also be composted: In one experiment, it took 10 weeks to completely degrade in soil.

A diagram of Lia's features
Lia

Like other pregnancy tests available at the drug store, Lia’s results are based on the concentration of human chorionic gonadotropin (a pregnancy hormone) in your pee. It’s FDA approved, and the company reports that it’s more than 99 percent accurate, comparable to other tests on the market.

No matter what the circumstances surrounding a pregnancy are, most people don’t want to share the fact that they could be pregnant with everyone they might share a bathroom with—most people wait several months into their pregnancy to announce the news—and even if they want to tell the world immediately, they probably don’t want to do so via trash can. Lia’s paper design makes it easy to dispose of the test without worrying about who might stumble upon your wastebasket. It’s also more sustainable and won’t clog up landfills like plastic tests. While people don’t use as many pregnancy tests as, say, plastic straws, the over-the-counter plastic pregnancy test market is still a huge one, and a contributor to environmental pollution. As a bonus, the lack of plastic makes Lia cheaper to produce, too.

Lia will eventually be available in stores and online. It’s scheduled to be released sometime in 2018.

[h/t Glamour]

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