CLOSE

Scientists Put a GIF Inside Living Bacteria

Researchers at Harvard University have figured out a way to embed moving images into the DNA of E. coli bacteria. The team described their process in the journal Nature.

It's a setup any spy would love: a code within a code. The paper authors see bacterial DNA as a form of information storage, almost like a computer's hard drive. As the science of gene editing technology advances, we're learning how to fit more—and more complex—information on the same equipment.

Enabling this advancement is a gene editing technique called CRISPR-Cas, which gives scientists access to certain immune-activating regions of bacterial DNA. Researchers have already used that access to engineer malaria-resistant mosquitoes and track down disease-causing pathogens. 

Other scientists have successfully inserted secret messages in E. coli's genetic blueprints. Some have even gotten the bacteria to hold pictures. But until now, none of those pictures have moved.

The Harvard team wanted to see how far CRISPR-Cas could get them. First, they had to select their images. And while some researchers may have taken this opportunity to immortalize a goofy cat GIF, the Harvard team wanted the content of the first-ever bacterial home movies to have significance.

Eadweard Muybridge was a 19th-century photographer whose work blurred the line between art and science. Muybridge pushed the camera technology of the time to its limits, using what was then high-speed imaging to capture incredible shots of people and other animals in motion. His photos showed us the potential of both cameras and our bodies.

And so the authors of the new paper thought it would be appropriate to make their first moving image a Muybridge—specifically, his groundbreaking image of a horse in full gallop. They converted the images to pixels, then converted those pixels to nucleotides, which are often called the building blocks of DNA. They popped those nucleotides into the bacteria's genetic code, then ran the DNA through a sequencer to see if the pixel information stayed in place. It did.

But lead author Seth Shipman says printing images is just the beginning. He envisions a world in which our cells work like microscopic cameras, recording the state and goings-on inside our bodies.

"What we want this system to be used for, eventually, is not to encode information that we already have, but for a way for cells to go out and gather information that we don't have access to," Shipman told Popular Science. "If we could have them collect data and then store that data in their genomes, then we might have access to completely new types of information."

If that concept sounds kind of creepy to you, we have some good news: It's still a long way off.

[h/t Popular Science]

nextArticle.image_alt|e
iStock
arrow
science
Scientists Analyze the Moods of 90,000 Songs Based on Music and Lyrics
iStock
iStock

Based on the first few seconds of a song, the part before the vocalist starts singing, you can judge whether the lyrics are more likely to detail a night of partying or a devastating breakup. The fact that musical structures can evoke certain emotions just as strongly as words can isn't a secret. But scientists now have a better idea of which language gets paired with which chords, according to their paper published in Royal Society Open Science.

For their study, researchers from Indiana University downloaded 90,000 songs from Ultimate Guitar, a site that allows users to upload the lyrics and chords from popular songs for musicians to reference. Next, they pulled data from labMT, which crowd-sources the emotional valence (positive and negative connotations) of words. They referred to the music recognition site Gracenote to determine where and when each song was produced.

Their new method for analyzing the relationship between music and lyrics confirmed long-held knowledge: that minor chords are associated with sad feelings and major chords with happy ones. Words with a negative valence, like "pain," "die," and "lost," are all more likely to fall on the minor side of the spectrum.

But outside of major chords, the researchers found that high-valence words tend to show up in a surprising place: seventh chords. These chords contain four notes at a time and can be played in both the major and minor keys. The lyrics associated with these chords are positive all around, but their mood varies slightly depending on the type of seventh. Dominant seventh chords, for example, are often paired with terms of endearment, like "baby", or "sweet." With minor seventh chords, the words "life" and "god" are overrepresented.

Using their data, the researchers also looked at how lyric and chord valence differs between genres, regions, and eras. Sixties rock ranks highest in terms of positivity while punk and metal occupy the bottom slots. As for geography, Scandinavia (think Norwegian death metal) produces the dreariest music while songs from Asia (like K-Pop) are the happiest. So if you're looking for a song to boost your mood, we suggest digging up some Asian rock music from the 1960s, and make sure it's heavy on the seventh chords.

nextArticle.image_alt|e
NASA/JPL, YouTube
arrow
Space
Watch NASA Test Its New Supersonic Parachute at 1300 Miles Per Hour
NASA/JPL, YouTube
NASA/JPL, YouTube

NASA’s latest Mars rover is headed for the Red Planet in 2020, and the space agency is working hard to make sure its $2.1 billion project will land safely. When the Mars 2020 rover enters the Martian atmosphere, it’ll be assisted by a brand-new, advanced parachute system that’s a joy to watch in action, as a new video of its first test flight shows.

Spotted by Gizmodo, the video was taken in early October at NASA’s Wallops Flight Facility in Virginia. Narrated by the technical lead from the test flight, the Jet Propulsion Laboratory’s Ian Clark, the two-and-a-half-minute video shows the 30-mile-high launch of a rocket carrying the new, supersonic parachute.

The 100-pound, Kevlar-based parachute unfurls at almost 100 miles an hour, and when it is entirely deployed, it’s moving at almost 1300 miles an hour—1.8 times the speed of sound. To be able to slow the spacecraft down as it enters the Martian atmosphere, the parachute generates almost 35,000 pounds of drag force.

For those of us watching at home, the video is just eye candy. But NASA researchers use it to monitor how the fabric moves, how the parachute unfurls and inflates, and how uniform the motion is, checking to see that everything is in order. The test flight ends with the payload crashing into the ocean, but it won’t be the last time the parachute takes flight in the coming months. More test flights are scheduled to ensure that everything is ready for liftoff in 2020.

[h/t Gizmodo]

SECTIONS

arrow
LIVE SMARTER
More from mental floss studios