How Do Hormones Affect Emotions?

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How Do Hormones Affect Emotions?

Ray Schilling:

1. Serotonin production in the brain is important to prevent depression. Datis Kharrazian’s book Why isn’t my brain working? offers several scenarios that can cause depression and he has examples of cases that were cured of depression. He points out that deficiencies in two major brain transmitters can cause depression: serotonin and dopamine.

Serotonin is produced in the midbrain from the amino acid tryptophan in two biochemical steps. These biochemical conversions require iron, vitamin B6, vitamin B12, niacin, folic acid, and magnesium as co-factors. But you also need the “large neutral amino acid transporter” (LNAA) to transport tryptophan through the blood-brain barrier into the brain.

Dopamine is a neurotransmitter that is produced in the frontal lobes of the brain. It is also necessary for learning. Dopamine is synthesized by the brain from tyrosine, which has to be manufactured in the liver from the amino acid phenylalanine. You need to have a healthy liver to produce tyrosine, which needs to be transported through the blood-brain barrier into the brain; similar to tryptophan this requires the “large neutral amino acid transporter” (LNAA). People with hepatitis, fatty liver, insulin resistance or diabetes may have problems with the LNAA transporter, which can cause dopamine deficiency. But as mentioned earlier they may also have low serotonin because tryptophan was not transported into the brain. This will happen with sugar overconsumption, as insulin resistance develops and affects the LNAA transporter resulting in both low serotonin and dopamine.

2. When testosterone is missing in an aging man, this causes low energy, depression, a lack of drive, and erectile dysfunction. You replace testosterone in appropriate doses and all of that normalizes. The reason for that is that many key organs including the brain have testosterone receptors. They need to be activated regularly by testosterone for normal organ function. Women need a small amount of testosterone as well to feel normal.

3. Estrogen hormones are the female hormones. If they are normal and balanced by progesterone (from the corpus luteum in the second half of the menstrual cycle) a woman feels well. There is a condition called estrogen dominance where too much estrogen is circulating in relation to progesterone, and these women have the following symptoms:

  • Irregular or otherwise abnormal menstrual periods
  • Decreased sex drive
  • Bloating (water retention)
  • Breast swelling and tenderness.
  • Fibrocystic breasts.
  • Headaches (especially premenstrually)
  • Mood swings (most often irritability and depression)

If the ratio can be normalized between progesterone and estrogen by the use of bioidentical progesterone, these symptoms disappear and the woman feels normal. Again it is the stimulation of the hormone receptors in just the right manner, which stabilizes the mood and leads to normal body function.

4. If thyroid hormones are missing, the person gets depressed and has a lack of energy. Thyroid hormones are stimulating cell function in all the body cells including the brain. Again this is transmitted by hormone receptors in the cells. It is easy for a physician to measure thyroid hormone levels (TSH and thyroid hormone levels) and to rectify the situation by ordering the right amount of thyroid hormones. When thyroid hormone receptor stimulation is normalized, all of the symptoms disappear and the person will feel normal again.

Conclusion

Hormones do not act in isolation, but in concert. Thyroid hormones give the body cells energy. Other hormones add to this and at the end we feel normal.

This post originally appeared on Quora. Click here to view.

Presidents Day vs. President's Day vs. Presidents' Day: Which One Is It?

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Happy Presidents’ Day! Or is it President’s Day? Or Presidents Day? What you call the national holiday depends on where you are, who you’re honoring, and how you think we’re celebrating.

Saying "President’s Day" implies that the day belongs to a singular president, such as George Washington or Abraham Lincoln, whose birthdays are the basis for the holiday. On the other hand, referring to it as "Presidents’ Day" means that the day belongs to all of the presidents—that it’s their day collectively. Finally, calling the day "Presidents Day"—plural with no apostrophe—would indicate that we’re honoring all POTUSes past and present (yes, even Andrew Johnson), but that no one president actually owns the day.

You would think that in the 140 years since "Washington’s Birthday" was declared a holiday in 1879, someone would have officially declared a way to spell the day. But in fact, even the White House itself hasn’t chosen a single variation for its style guide. They spelled it “President’s Day” here and “Presidents’ Day” here.


Wikimedia Commons // Public Domain

Maybe that indecision comes from the fact that Presidents Day isn’t even a federal holiday. The federal holiday is technically still called “Washington’s Birthday,” and states can choose to call it whatever they want. Some states, like Iowa, don’t officially acknowledge the day at all. And the location of the punctuation mark is a moot point when individual states choose to call it something else entirely, like “George Washington’s Birthday and Daisy Gatson Bates Day” in Arkansas, or “Birthdays of George Washington and Thomas Jefferson” in Alabama. (Alabama loves to split birthday celebrations, by the way; the third Monday in January celebrates both Martin Luther King Jr. and Robert E. Lee.)

You can look to official grammar sources to declare the right way, but even they don’t agree. The AP Stylebook prefers “Presidents Day,” while Chicago Style uses “Presidents’ Day.”

The bottom line: There’s no rhyme or reason to any of it. Go with what feels right. And even then, if you’re in one of those states that has chosen to spell it “President’s Day”—Washington, for example—and you use one of the grammar book stylings instead, you’re still technically wrong.

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Full vs. Queen Mattress: What's the Difference?

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If you’re in the market for a new mattress this Presidents Day weekend (the holiday is traditionally a big one for mattress retailers), one of the first decisions you’ll need to make is regarding size. Most people know a king mattress offers the most real estate, but the difference between a full-sized mattress and a queen-sized one provokes more curiosity. Is it strictly a matter of width, or are depth and length factors? Is there a recommended amount of space for each slumbering occupant?

Fortunately, mattress manufacturers have made things easier by adhering to a common set of dimensions, which are sized as follows:

Crib: 27 inches wide by 52 inches long

Twin: 38 inches wide by 75 inches long

Full: 53 inches wide by 75 inches long

Queen: 60 inches wide by 80 inches long

King: 76 inches wide by 80 inches long

Depth can vary across styles. And while you can find some outliers—there’s a twin XL, which adds 5 inches to the length of a standard twin, or a California king, which subtracts 4 inches from the width and adds it to the length—the four adult sizes listed above are typically the most common, with the queen being the most popular. It's 7 inches wider than a full (sometimes called a “double”) mattress and 5 inches longer.

In the 1940s, consumers didn’t have as many options. Most people bought either a twin or full mattress. But in the 1950s, a post-war economy boost and a growing average height for Americans contributed to an increasing demand for larger bedding.

Still, outsized beds were a novelty and took some time to fully catch on. Today, bigger is usually better. If your bed is intended for a co-sleeping arrangement with a partner, chances are you’ll be looking at a queen. A full mattress leaves each occupant only 26.5 inches of width, which is actually slightly narrower than a crib mattress intended for babies and toddlers. A queen offers 30 inches, which is more generous but still well below the space provided by a person sleeping alone in a twin or full. For maximum couple comfort, you might want to consider a king, which is essentially like two twin beds being pushed together.

Your preference could be limited by the size of your bedroom—you might not be able to fit a nightstand on each side of a wider bed, for example—and whether you’ll have an issue getting a larger mattress up stairs and/or around tricky corners. Your purchase will also come down to a laundry list of options like material and firmness, but knowing which size you want helps narrow down your choices.

One lingering mystery remains: Why do we tend to shop for mattresses on Presidents Day weekend? One reason could be time. The three-day weekend is one of the first extended breaks since the December holidays, giving people an opportunity to trial different mattress types and deliberate with a partner. Shopping Saturday and Sunday allows people to sleep on it before making a decision.

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