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15 Useful Facts About Lyme Disease

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Stringer/Getty Images

As summer nears and you spend more time outdoors in one of the many beautiful natural spots in the United States, be sure to dress for the season—tick season, that is. Some experts say 2017 may be an especially tick-infested year. Deer ticks (Ixodes scapularis) carry a bacteria that causes Lyme disease, an infection from a bacterium that coils waiting in their insect bodies. Lyme-carrying deer ticks are especially prevalent in the upper East Coast, the upper Midwest, northern California, and the Oregon coast. While not every tick carries the bacteria that lead to infection—and some carry other pathogens—it’s best to take precautions to prevent bites, and seek medical attention if you have been bitten. The infection can cause long-lasting damage if not treated early. Here are 15 facts you need to know about Lyme disease.

1. LYME DISEASE IS CAUSED BY COILED BACTERIA.

Lyme disease is caused by the bacterium Borrelia burgdorferi, a spirochete, or tightly coiled bacterium that looks like a tiny spring under a microscope. Spirochetes are very simple, slow-replicating bacteria that require a mammalian or avian host to survive. According to Timothy Sellati, chair of the infectious diseases department at Southern Research, a nonprofit research institution in Birmingham, Alabama, “It takes on the order of 18–20 hours for a single spirochete to divide into two.” That’s incredibly slow, compared to other bacteria like E. coli, which can replicate every 20 minutes. Because Borrelia replicates so slowly, and they don’t reach high numbers, “They do not show up easily in a blood test,” Sellati says.

2. TICKS PREFER A LONG MEAL.

Sellati explains that ticks are very different feeders from mosquitoes, which he calls “hit-and-run feeders.” Ticks will feed over a period of three to five days before they become fully engorged. Female ticks generally only take three “blood meals,” he says, in the duration of their lifespan. They take one blood meal after hatching from their egg into the larval stage, another after they molt into their nymphal stage—the stage where they are most likely to bite you—and a final “big meal” in preparation for laying thousands of eggs. Adult male ticks generally don’t feed, he says.

3. THEY ARE A VIRULENT DISEASE VECTOR …

When an infected tick bites a human, the waiting spirochetes—which live essentially dormant in the tick’s gut until environmental cues such as changes in temperature and oxygen availability awaken them—travel from the tick’s gut to its saliva glands. “From the saliva glands they can literally be spat into the bloodstream that the tick is feeding on,” Sellati says. Once they enter the bloodstream, spirochetes travel to various body tissues, because if they stay too long in the bloodstream, they’ll get killed by their host's immune system. “Once it gets away from site of inoculation, it shows a bias toward joints, heart, central nervous system,” Sellati says.

4. … WHICH LEADS TO INFLAMMATION.

“The bacteria has components that are very effective at eliciting an inflammatory response,” Sellati explains. While Borrelia don’t produce toxins like other bacteria, they do incite inflammation in sensitive parts of the body such as the joints, heart, and brain. “That inflammatory response is important to help kill and clear the spirochetes, but it causes collateral damage as well.”

5. INFECTIONS MAY BEGIN WITH A BULL'S-EYE.

The first symptom to look for in about 80 to 90 percent of Lyme cases is a telltale rash of an infected tick bite, called an erythema migrans (EM) rash, which looks a lot like a red bull's-eye, and usually appears at the site of a tick bite within seven to 14 days, according to the American Lyme Disease Foundation. However, the rash does not appear in every instance of Lyme disease, so if you’re bitten, you should visit a doctor immediately. You may also experience flu-like symptoms or joint pains in the first month after the bite.

6. DON'T WAIT TO GET TREATMENT.

If you don't see the tick bite, and don't treat early symptoms, the spirochetes continue to spread throughout your body and can cause more severe symptoms, including fatigue, stiff or aching neck, tingling or numbness in your extremities, and even paralysis of your face. Even more debilitating symptoms of later-stage Lyme disease can include severe headaches, painful arthritis and swelling of joints, cardiac abnormalities, and central nervous system debilitations leading to cognitive disorders.

7. IF CAUGHT EARLY, IT'S USUALLY HIGHLY TREATABLE …

When the disease is caught in its early stages, and treated with antibiotics, it’s curable, Sellati says. Even later stages of the disease can be treated, but the longer an infection goes untreated, the more severe the symptoms and damage can become.

8. … BUT SOME PATIENTS EXPERIENCE SYMPTOMS FOR MUCH LONGER.

Scientists are not entirely sure why a subset of patients have recurrent symptoms of the illness in the months and even years following treatment, known as post-treatment Lyme disease syndrome. “It’s not clear if there is a persistence of live replicating bacteria in some immune privileged niche where they’re protected from exposure to antibiotics,” Sellati says, or if it’s simply the subsequent inflammation stirred up in the body that refuses to go back to normal. “What drives that is not entirely clear.”

9. YOUR GENETICS MAY DICTATE YOUR TREATMENT.

Sellati’s lab has been exploring whether genetics plays a role in who recovers after treatment and who doesn’t. “We have some evidence that your genetic makeup can actually predispose you to developing post-treatment Lyme disease syndrome," Sellati says, and adds it will require more research. They believe they might be able to isolate genetic markers that will tell doctors if antibiotics alone will work, or if the patient might need additional treatment.

10. FEAR THE ENGORGED TICK (BUT DON'T PANIC).

The good news is, even if a tick bites you, if it isn’t yet fully engorged on your blood, chances are good it hasn’t been there long enough to transmit the spirochetes that lead to infection. However, it’s always better to be safe, and pay attention to any symptoms that occur thereafter. “The sooner you can remove a tick from your body, whether it’s feeding or not, the better. If the tick is feeding for less than 24 hours, the likelihood of being infected with Borellia is significantly reduced,” Sellati says.

11. AREAS WITH MICE HAVE MORE LYME DISEASE.

Wherever you find mice and deer you’re very likely to find ticks as well. In fact, Sellati says, mice in all forms—but especially the white-footed mouse—are what infectious researchers call a “maintenance reservoir.” Sellati says. “They maintain the bacteria in the wild so that new ticks can acquire it.” Since spirochetes tend to stay in the bloodstream of mice much longer than they do in humans, that’s how ticks have such an endless supply of the bacteria. “If you got rid of all the mice in the world, you would either come very close to or significantly reduce the population of Borellia in the environment. You’d have a significant decrease in Lyme,” he emphasizes.

12. YOU CAN TAKE SIMPLE STEPS TO PROTECT YOURSELF.

Wear clothes with the most coverage possible. Spray yourself with anti-tick sprays. But no matter what, always do a tick check after you return from the outdoors just to be safe. And if you start to feel any of the symptoms mentioned earlier within a month of a tick bite, don’t wait to visit your doctor.

13. CHECK YOUR CREVICES.

Ticks are not opposed to biting you wherever they can reach, but they have a preference for your warm, moist crevices, such as armpits, backs of the knee, groin, base of the head, and nape of your neck.

14. SKIP SOME OF THOSE "TIPS" FOR REMOVING TICKS THAT YOU'VE HEARD ABOUT.

No matter how many YouTube tutorials you’ve watched, Sellati recommends that you do not use heat, like a match or a lighter, to burn a tick off. The same goes for “goops” such as petroleum jelly, alcohol, or hand sanitizer. Since the spirochetes are transmitted through tick saliva, Sellati warns, “If you try to do those things, you’re only going to piss the tick off, and a pissed-off tick spits a lot, and you're more likely to get more bacteria into your bloodstream.”

15. INSTEAD, USE SLOW, STEADY PRESSURE—AND SOME TWEEZERS.

Take a small pair of forceps or tweezers, Sellati instructs, and gently grasp the tick as close to the skin’s surface as possible, “then pull the tick straight up slowly, which pulls the mouth part out of the skin, and then just dab the area with alcohol to disinfect.” A tick’s mouthparts are like tiny barbed hooks, designed to pierce the skin and stay there. “Then they have secretions that cement the mouthparts to the skin, because they have to feed over a long time and they don’t want to be knocked off while they sit and sip.”

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More Details Emerge About 'Oumuamua, Earth's First-Recorded Interstellar Visitor
 NASA/JPL-Caltech
NASA/JPL-Caltech

In October, scientists using the University of Hawaii's Pan-STARRS 1 telescope sighted something extraordinary: Earth's first confirmed interstellar visitor. Originally called A/2017 U1, the once-mysterious object has a new name—'Oumuamua, according to Scientific American—and researchers continue to learn more about its physical properties. Now, a team from the University of Hawaii's Institute of Astronomy has published a detailed report of what they know so far in Nature.

Fittingly, "'Oumuamua" is Hawaiian for "a messenger from afar arriving first." 'Oumuamua's astronomical designation is 1I/2017 U1. The "I" in 1I/2017 stands for "interstellar." Until now, objects similar to 'Oumuamua were always given "C" and "A" names, which stand for either comet or asteroid. New observations have researchers concluding that 'Oumuamua is unusual for more than its far-flung origins.

It's a cigar-shaped object 10 times longer than it is wide, stretching to a half-mile long. It's also reddish in color, and is similar in some ways to some asteroids in our solar system, the BBC reports. But it's much faster, zipping through our system, and has a totally different orbit from any of those objects.

After initial indecision about whether the object was a comet or an asteroid, the researchers now believe it's an asteroid. Long ago, it might have hurtled from an unknown star system into our own.

'Oumuamua may provide astronomers with new insights into how stars and planets form. The 750,000 asteroids we know of are leftovers from the formation of our solar system, trapped by the Sun's gravity. But what if, billions of years ago, other objects escaped? 'Oumuamua shows us that it's possible; perhaps there are bits and pieces from the early years of our solar system currently visiting other stars.

The researchers say it's surprising that 'Oumuamua is an asteroid instead of a comet, given that in the Oort Cloud—an icy bubble of debris thought to surround our solar system—comets are predicted to outnumber asteroids 200 to 1 and perhaps even as high as 10,000 to 1. If our own solar system is any indication, it's more likely that a comet would take off before an asteroid would.

So where did 'Oumuamua come from? That's still unknown. It's possible it could've been bumped into our realm by a close encounter with a planet—either a smaller, nearby one, or a larger, farther one. If that's the case, the planet remains to be discovered. They believe it's more likely that 'Oumuamua was ejected from a young stellar system, location unknown. And yet, they write, "the possibility that 'Oumuamua has been orbiting the galaxy for billions of years cannot be ruled out."

As for where it's headed, The Atlantic's Marina Koren notes, "It will pass the orbit of Jupiter next May, then Neptune in 2022, and Pluto in 2024. By 2025, it will coast beyond the outer edge of the Kuiper Belt, a field of icy and rocky objects."

Last month, University of Wisconsin–Madison astronomer Ralf Kotulla and scientists from UCLA and the National Optical Astronomy Observatory (NOAO) used the WIYN Telescope on Kitt Peak, Arizona, to take some of the first pictures of 'Oumuamua. You can check them out below.

Images of an interloper from beyond the solar system — an asteroid or a comet — were captured on Oct. 27 by the 3.5-meter WIYN Telescope on Kitt Peak, Ariz.
Images of 'Oumuamua—an asteroid or a comet—were captured on October 27.
WIYN OBSERVATORY/RALF KOTULLA

U1 spotted whizzing through the Solar System in images taken with the WIYN telescope. The faint streaks are background stars. The green circles highlight the position of U1 in each image. In these images U1 is about 10 million times fainter than the faint
The green circles highlight the position of U1 in each image against faint streaks of background stars. In these images, U1 is about 10 million times fainter than the faintest visible stars.
R. Kotulla (University of Wisconsin) & WIYN/NOAO/AURA/NSF

Color image of U1, compiled from observations taken through filters centered at 4750A, 6250A, and 7500A.
Color image of U1.
R. Kotulla (University of Wisconsin) & WIYN/NOAO/AURA/NSF

Editor's note: This story has been updated.

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Scientists Analyze the Moods of 90,000 Songs Based on Music and Lyrics
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Based on the first few seconds of a song, the part before the vocalist starts singing, you can judge whether the lyrics are more likely to detail a night of partying or a devastating breakup. The fact that musical structures can evoke certain emotions just as strongly as words can isn't a secret. But scientists now have a better idea of which language gets paired with which chords, according to their paper published in Royal Society Open Science.

For their study, researchers from Indiana University downloaded 90,000 songs from Ultimate Guitar, a site that allows users to upload the lyrics and chords from popular songs for musicians to reference. Next, they pulled data from labMT, which crowd-sources the emotional valence (positive and negative connotations) of words. They referred to the music recognition site Gracenote to determine where and when each song was produced.

Their new method for analyzing the relationship between music and lyrics confirmed long-held knowledge: that minor chords are associated with sad feelings and major chords with happy ones. Words with a negative valence, like "pain," "die," and "lost," are all more likely to fall on the minor side of the spectrum.

But outside of major chords, the researchers found that high-valence words tend to show up in a surprising place: seventh chords. These chords contain four notes at a time and can be played in both the major and minor keys. The lyrics associated with these chords are positive all around, but their mood varies slightly depending on the type of seventh. Dominant seventh chords, for example, are often paired with terms of endearment, like "baby", or "sweet." With minor seventh chords, the words "life" and "god" are overrepresented.

Using their data, the researchers also looked at how lyric and chord valence differs between genres, regions, and eras. Sixties rock ranks highest in terms of positivity while punk and metal occupy the bottom slots. As for geography, Scandinavia (think Norwegian death metal) produces the dreariest music while songs from Asia (like K-Pop) are the happiest. So if you're looking for a song to boost your mood, we suggest digging up some Asian rock music from the 1960s, and make sure it's heavy on the seventh chords.

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