15 Useful Facts About Lyme Disease

Stringer/Getty Images
Stringer/Getty Images

As summer nears and you spend more time outdoors in one of the many beautiful natural spots in the United States, be sure to dress for the season—tick season, that is. Some experts say 2017 may be an especially tick-infested year. Deer ticks (Ixodes scapularis) carry a bacteria that causes Lyme disease, an infection from a bacterium that coils waiting in their insect bodies. Lyme-carrying deer ticks are especially prevalent in the upper East Coast, the upper Midwest, northern California, and the Oregon coast. While not every tick carries the bacteria that lead to infection—and some carry other pathogens—it’s best to take precautions to prevent bites, and seek medical attention if you have been bitten. The infection can cause long-lasting damage if not treated early. Here are 15 facts you need to know about Lyme disease.

1. LYME DISEASE IS CAUSED BY COILED BACTERIA.

Lyme disease is caused by the bacterium Borrelia burgdorferi, a spirochete, or tightly coiled bacterium that looks like a tiny spring under a microscope. Spirochetes are very simple, slow-replicating bacteria that require a mammalian or avian host to survive. According to Timothy Sellati, chair of the infectious diseases department at Southern Research, a nonprofit research institution in Birmingham, Alabama, “It takes on the order of 18–20 hours for a single spirochete to divide into two.” That’s incredibly slow, compared to other bacteria like E. coli, which can replicate every 20 minutes. Because Borrelia replicates so slowly, and they don’t reach high numbers, “They do not show up easily in a blood test,” Sellati says.

2. TICKS PREFER A LONG MEAL.

Sellati explains that ticks are very different feeders from mosquitoes, which he calls “hit-and-run feeders.” Ticks will feed over a period of three to five days before they become fully engorged. Female ticks generally only take three “blood meals,” he says, in the duration of their lifespan. They take one blood meal after hatching from their egg into the larval stage, another after they molt into their nymphal stage—the stage where they are most likely to bite you—and a final “big meal” in preparation for laying thousands of eggs. Adult male ticks generally don’t feed, he says.

3. THEY ARE A VIRULENT DISEASE VECTOR …

When an infected tick bites a human, the waiting spirochetes—which live essentially dormant in the tick’s gut until environmental cues such as changes in temperature and oxygen availability awaken them—travel from the tick’s gut to its saliva glands. “From the saliva glands they can literally be spat into the bloodstream that the tick is feeding on,” Sellati says. Once they enter the bloodstream, spirochetes travel to various body tissues, because if they stay too long in the bloodstream, they’ll get killed by their host's immune system. “Once it gets away from site of inoculation, it shows a bias toward joints, heart, central nervous system,” Sellati says.

4. … WHICH LEADS TO INFLAMMATION.

“The bacteria has components that are very effective at eliciting an inflammatory response,” Sellati explains. While Borrelia don’t produce toxins like other bacteria, they do incite inflammation in sensitive parts of the body such as the joints, heart, and brain. “That inflammatory response is important to help kill and clear the spirochetes, but it causes collateral damage as well.”

5. INFECTIONS MAY BEGIN WITH A BULL'S-EYE.

The first symptom to look for in about 80 to 90 percent of Lyme cases is a telltale rash of an infected tick bite, called an erythema migrans (EM) rash, which looks a lot like a red bull's-eye, and usually appears at the site of a tick bite within seven to 14 days, according to the American Lyme Disease Foundation. However, the rash does not appear in every instance of Lyme disease, so if you’re bitten, you should visit a doctor immediately. You may also experience flu-like symptoms or joint pains in the first month after the bite.

6. DON'T WAIT TO GET TREATMENT.

If you don't see the tick bite, and don't treat early symptoms, the spirochetes continue to spread throughout your body and can cause more severe symptoms, including fatigue, stiff or aching neck, tingling or numbness in your extremities, and even paralysis of your face. Even more debilitating symptoms of later-stage Lyme disease can include severe headaches, painful arthritis and swelling of joints, cardiac abnormalities, and central nervous system debilitations leading to cognitive disorders.

7. IF CAUGHT EARLY, IT'S USUALLY HIGHLY TREATABLE …

When the disease is caught in its early stages, and treated with antibiotics, it’s curable, Sellati says. Even later stages of the disease can be treated, but the longer an infection goes untreated, the more severe the symptoms and damage can become.

8. … BUT SOME PATIENTS EXPERIENCE SYMPTOMS FOR MUCH LONGER.

Scientists are not entirely sure why a subset of patients have recurrent symptoms of the illness in the months and even years following treatment, known as post-treatment Lyme disease syndrome. “It’s not clear if there is a persistence of live replicating bacteria in some immune privileged niche where they’re protected from exposure to antibiotics,” Sellati says, or if it’s simply the subsequent inflammation stirred up in the body that refuses to go back to normal. “What drives that is not entirely clear.”

9. YOUR GENETICS MAY DICTATE YOUR TREATMENT.

Sellati’s lab has been exploring whether genetics plays a role in who recovers after treatment and who doesn’t. “We have some evidence that your genetic makeup can actually predispose you to developing post-treatment Lyme disease syndrome," Sellati says, and adds it will require more research. They believe they might be able to isolate genetic markers that will tell doctors if antibiotics alone will work, or if the patient might need additional treatment.

10. FEAR THE ENGORGED TICK (BUT DON'T PANIC).

The good news is, even if a tick bites you, if it isn’t yet fully engorged on your blood, chances are good it hasn’t been there long enough to transmit the spirochetes that lead to infection. However, it’s always better to be safe, and pay attention to any symptoms that occur thereafter. “The sooner you can remove a tick from your body, whether it’s feeding or not, the better. If the tick is feeding for less than 24 hours, the likelihood of being infected with Borellia is significantly reduced,” Sellati says.

11. AREAS WITH MICE HAVE MORE LYME DISEASE.

Wherever you find mice and deer you’re very likely to find ticks as well. In fact, Sellati says, mice in all forms—but especially the white-footed mouse—are what infectious researchers call a “maintenance reservoir.” Sellati says. “They maintain the bacteria in the wild so that new ticks can acquire it.” Since spirochetes tend to stay in the bloodstream of mice much longer than they do in humans, that’s how ticks have such an endless supply of the bacteria. “If you got rid of all the mice in the world, you would either come very close to or significantly reduce the population of Borellia in the environment. You’d have a significant decrease in Lyme,” he emphasizes.

12. YOU CAN TAKE SIMPLE STEPS TO PROTECT YOURSELF.

Wear clothes with the most coverage possible. Spray yourself with anti-tick sprays. But no matter what, always do a tick check after you return from the outdoors just to be safe. And if you start to feel any of the symptoms mentioned earlier within a month of a tick bite, don’t wait to visit your doctor.

13. CHECK YOUR CREVICES.

Ticks are not opposed to biting you wherever they can reach, but they have a preference for your warm, moist crevices, such as armpits, backs of the knee, groin, base of the head, and nape of your neck.

14. SKIP SOME OF THOSE "TIPS" FOR REMOVING TICKS THAT YOU'VE HEARD ABOUT.

No matter how many YouTube tutorials you’ve watched, Sellati recommends that you do not use heat, like a match or a lighter, to burn a tick off. The same goes for “goops” such as petroleum jelly, alcohol, or hand sanitizer. Since the spirochetes are transmitted through tick saliva, Sellati warns, “If you try to do those things, you’re only going to piss the tick off, and a pissed-off tick spits a lot, and you're more likely to get more bacteria into your bloodstream.”

15. INSTEAD, USE SLOW, STEADY PRESSURE—AND SOME TWEEZERS.

Take a small pair of forceps or tweezers, Sellati instructs, and gently grasp the tick as close to the skin’s surface as possible, “then pull the tick straight up slowly, which pulls the mouth part out of the skin, and then just dab the area with alcohol to disinfect.” A tick’s mouthparts are like tiny barbed hooks, designed to pierce the skin and stay there. “Then they have secretions that cement the mouthparts to the skin, because they have to feed over a long time and they don’t want to be knocked off while they sit and sip.”

Some Fish Eggs Can Hatch After Being Pooped Out by Swans

iStock/olaser
iStock/olaser

A question that’s often baffled scientists is how certain species of fish can sometimes appear—and even proliferate—in isolated bodies of water not previously known to harbor them. A new study has demonstrated that the most unlikely explanation might actually be correct: It’s possible they fell from the sky.

Specifically, from the rear end of a swan.

A study in the journal Ecology by researchers at the Unisinos University in Brazil found that killifish eggs can, in rare cases, survive being swallowed by swans, enduring a journey through their digestive tracts before being excreted out. This kind of fecal public transportation system explains how killifish can pop up in ponds, flood waters, and other water bodies that would seem an unlikely place for species to suddenly appear.

After discovering that some plants could survive being ingested and then flourish in swan poop, researchers took notice of a killifish egg present in a frozen fecal sample. They set about mixing two species of killifish eggs into the food supply of coscoroba swans living in a zoo. After waiting a day, they collected the poop and dug in looking for the eggs.

Of the 650 eggs they estimated to have been ingested by the swans, about five were left intact. Of those, three continued to develop. Two died of a fungal infection, but one survived, enduring 30 hours in the gut and hatching 49 days after being excreted.

Because killifish eggs have a thick outer membrane, or chorion, they stand a chance of coming through the digestive tract of an animal intact. Not all of what a swan ingests will be absorbed; their stomachs are built to extract nutrients quickly and get rid of the whatever's left so the birds can eat again. In rare cases, that can mean an egg that can go on to prosper.

Not all fish eggs are so durable, and not all fish are quite like the killifish. Dubbed the "most extreme" fish on Earth by the BBC, killifish have adapted to popping up in strange environments where water may eventually dry up. They typically live for a year and deposit eggs that can survive in soil, delaying their development until conditions—say, not being inside a swan—are optimal. One species, the mangrove killifish, can even breathe through its skin. When water recedes, they can survive on land for over two months, waddling on their bellies or using their tails to "jump" and eat insects. A fish that can survive on dry land probably doesn't sweat having to live in poop.

The researchers plan to study carp eggs next to see if they, too, can go through a lot of crap to get to where they’re going.

[h/t The New York Times]

8 Facts About the Animals of Chernobyl

iStock/Tijuana2014
iStock/Tijuana2014

Three decades after the Chernobyl disaster—the world’s worst nuclear accident—signs of life are returning to the exclusion zone. Wild animals in Chernobyl are flourishing within the contaminated region; puppies roaming the area are capturing the hearts of thousands. Tourists who have watched the critically acclaimed HBO series Chernobyl are taking selfies with the ruins. Once thought to be forever uninhabitable, the Chernobyl Exclusion Zone has become a haven for flora and fauna that prove that life, as they say in Jurassic Park, finds a way.

1. The animals of Chernobyl survived against all odds.

The effects of the radioactive explosion at the Chernobyl nuclear power plant on April 26, 1986 devastated the environment. Around the plant and in the nearby city of Pripyat in Ukraine, the Chernobyl disaster’s radiation caused the leaves of thousands of trees to turn a rust color, giving a new name to the surrounding woods—the Red Forest. Workers eventually bulldozed and buried the radioactive trees. Squads of Soviet conscripts also were ordered to shoot any stray animals within the 1000-square-mile Chernobyl Exclusion Zone. Though experts today believe parts of the zone will remain unsafe for humans for another 20,000 years, numerous animal and plant species not only survived, but thrived.

2. Bears and wolves outnumber humans around the Chernobyl disaster site.

While humans are strictly prohibited from living in the Chernobyl Exclusion Zone, many other species have settled there. Brown bears, wolves, lynx, bison, deer, moose, beavers, foxes, badgers, wild boar, raccoon dogs, and more than 200 species of birds have formed their own ecosystem within the Chernobyl disaster area. Along with the larger animals, a variety of amphibians, fish, worms, and bacteria makes the unpopulated environment their home.

3. Most Chernobyl animals don’t look any different from their non-Chernobyl counterparts.

Stray puppies play in an abandoned, partially-completed cooling tower inside the exclusion zone at the Chernobyl nuclear power plant
Sean Gallup, Getty Images

Tour guides tell visitors not to pet Chernobyl animals due to potential radioactive particles in their fur, but some biologists have been surprised that the incidence of physical mutations appears lower than the blast of radiation would have suggested. There have been some oddities recorded within the area—such as partial albinism among barn swallows—but researchers think that the serious mutations mostly happened directly after the explosion. Today’s wild animals are sporting their normal number of limbs and aren’t glowing.

4. Radiation may have killed off Chernobyl’s insects.

In contrast to the large carnivores and other big fauna, bugs and spiders have seen a big drop in their numbers. A 2009 study in Biology Letters indicated that the more radiation there was in certain locations around the Chernobyl disaster area, the lower the population of invertebrates. A similar phenomenon occurred after the 2011 nuclear accident at the Fukushima nuclear power plant. Bird, cicada, and butterfly populations decreased, while other animal populations were not affected.

5. Despite looking normal, Chernobyl's animals and plants are mutants.

There may be no three-headed cows roaming around, but scientists have noted significant genetic changes in organisms affected by the disaster. According to a 2001 study in Biological Conservation, Chernobyl-caused genetic mutations in plants and animals increased by a factor of 20. Among breeding birds in the region, rare species suffered disproportional effects from the explosion’s radiation compared to common species. Further research is needed to understand how the increased mutations affect species’ reproductive rates, population size, genetic diversity, and other survival factors.

6. The absence of humans is returning Chernobyl to wilderness.

As WIRED points out, the Chernobyl disaster presents an unintended experiment in what Earth would be like without humans. Hunting is strictly illegal and living within the Chernobyl Exclusion Zone is not recommended. The fewer humans there are, the more nature can re-establish itself unencumbered by human activity. According to The Guardian, an official nature reserve recently created on the Belorussian side of the zone claims to be “Europe’s largest experiment in rewilding,” where animals are losing their fear of humans. In fact, a few species are actually living better within the Chernobyl Exclusion Zone than outside of it. Wolves were found to be seven times as abundant on the premises than in other, non-radioactive areas. Moose, roe deer, red deer, and wild boar were found to have similar numbers within the CEZ as compared to those in three uncontaminated nature reserves in Belarus.

7. An endangered wild horse is making a comeback thanks to Chernobyl.

A Przewalski's horse lays in a meadow
PATRICK PLEUL, AFP/Getty Images

British ecologists Mike Wood and Nick Beresford, who specialize in studying the effects of radiation on Chernobyl’s wildlife, observed that the Przewalski’s horse—an endangered wild species that originated in Mongolia—is thriving within the CEZ. In the late 1990s, about 30 Przewalski’s horses were released in the Ukrainian side of the CEZ. Based on camera trap images, Wood estimated that some of the original horses (identified by their brand markings) are still alive. Photos of juvenile horses and foals also indicated that the population is expanding.

8. You can adopt a Chernobyl puppy.

Hundreds of pooches—the descendants of dogs abandoned by their owners during the site’s evacuation on April 27, 1986—have made the desolate area their home. Until 2018, it was illegal to bring any animal out of the zone due to the risk of radiation contamination. But now, puppies cleared of radiation are getting a chance to find their forever homes. Spearheaded by the Clean Futures Fund and SPCA International, the management and adoption program ensures that the stray dogs are spayed, neutered, and vaccinated so they will be healthy and ready for adoption.

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