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10 Words That Will Win You Any Game of Scrabble

Hasbro
Hasbro

Whether you consider winning at Scrabble a case of extreme luck or supreme spelling ability, here are 10 words that—if conditions are right—will help you trump any opponent.

1. OXYPHENBUTAZONE

Definition: An anti-inflammatory medication used to treat arthritis and bursitis.
Conditions: The theoretically highest-possible scoring word under American Scrabble play—as calculated by Dan Stock of Ohio—has never actually been played … and probably never will (unless you’re really, really lucky). That’s because it has to be played across three triple word score squares and build on eight already-played (and perfectly positioned) tiles.
Points: 1778

2. QUIZZIFY

Definition: To quiz or question.
Conditions: Not only will you need to draw the game’s only Q and Z tiles (there’s only one of each), but a blank tile, too (in place of the second Z). Play this verb as your first word across two triple word squares with the Z on a double letter score square and you’ve got the game’s most valuable eight-letter bingo.
Points: 419

3. OXAZEPAM

Definition: An anti-anxiety drug.
Conditions: All that stress will melt away if you can build on one existing letter, play across two triple word score squares, place one of the most valuable tiles (i.e. X or Z) on a double letter score square and net a 50-point bingo.
Points: 392

4. QUETZALS

Definition: The national bird of Guatemala as well as one of its monetary units.
Conditions: Placement is everything to score this whopper of a word: Building on one letter, use all seven letters on your rack for a 50-point bingo, with Q and S on triple word score squares and Z on a double letter score space.
Points: 374

5. QUIXOTRY

Definition: A romantic or quixotic idea or action.
Conditions: In 2007, Michael Cresta used an already-played R and all seven of his tiles across two triple word score squares to earn the most points ever on a single turn, which aided in a second record for the full-time carpenter: the highest-ever individual game score (830 points).
Points: 365

6. GHERKINS

Definition: A small pickle, made from an immature cucumber.
Conditions: In 1985, Robert Kahn paid tribute to the pickle at the National Scrabble Championship in Boston—using an E and R already on the board—to set a record for a non-bingo word score.
Points: 180

7. QUARTZY

Definition: Resembling quartz.
Conditions: "Quartzy" held the record for highest-ever single turn score until "Quixotry" nearly doubled its total in 2007. Play it across a triple word score square with Z as a double letter score, and get a 50-point bingo for using all seven letters on your rack.
Points: 164

8. MUZJIKS

Definition: A Russian peasant.
Conditions: On its own (with no bonuses or extra points), "muzjiks" is worth an impressive 29 points. But exhaust all of your tiles on your first turn to spell it, and you’ll earn more than four times that—which is what player Jesse Inman did at the National Scrabble Championship in Orlando in 2008 to earn the record for highest opening score.
Points: 126

9. SYZYGY

Definition: An alignment of three celestial bodies.
Conditions: Forget trying to pronounce it (though, for the record, it’s "SIZ-i-jee"). Instead, just remember how to spell it—and that it’s worth 21 points au naturel. You’ll need one blank tile to make up for the lack of Ys (there are only two in the game). For a higher total, land the Z on a double letter score square and the final Y on a triple word score square.
Points: 93

10. ZA

Definition: Slang term for pizza.
Conditions: Big words are great and all, but two-letter words can also score big—and be especially annoying to your opponent. Build on two As—one directly below, the other directly to the right of a triple letter square—to spell this two-letter delectable across and down.
Points: 62

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Cell Free Technology
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This Pixel Kit Will Let You Play Tetris With Jellyfish DNA
Cell Free Technology
Cell Free Technology

Forget playing Tetris on your phone. Now you can play it with jellyfish DNA. Bixels is a DIY game kit that lets you code your own games using synthetic biology, lighting up a digital display with the help of DNA.

Its 8-by-8 pixel grid is programmed to turn on with the help of the same protein that makes jellyfish glow, called green fluorescent protein (GFP). But you can program it to do more than just passively shine. You can use your phone and the associated app to excite Bixels' fluorescent proteins and make them glow at different frequencies, producing red, blue, and green colors. Essentially, you can program it like you would any computer, but instead of electronics powering the system, it's DNA.

Two blue boxes hold Bixel pixel grids.

Researchers use green fluorescent protein all the time in lab experiments as an imaging agent to illuminate biological processes for study. With Bixels, all you need is a little programming to turn the colorful lights (tubes filled with GFP) into custom images or interactive games like Tetris or Snake. You can also use it to develop your own scientific experiments. (For experiment ideas, Bixels' creator, the Irish company Cell-Free Technology, suggests the curricula from BioBuilder.)

A screenshot shows a user assembling a Bixel kit on video.

A pixel kit is housed in a cardboard box that looks like a Game Boy.

Bixels is designed to be used by people with all levels of scientific knowledge, helping make the world of biotechnology more accessible to the public. Eventually, Cell-Free Technology wants to create a bio-computer even more advanced than Bixels. "Our ultimate goal is to build a personal bio-computer which, unlike current wearable devices, truly interacts with our bodies," co-founder Helene Steiner said in a press release.

Bixels - Play tetris with DNA from Cell-Free Technology on Vimeo.

You can buy your own Bixel kit on Kickstarter for roughly $118. It's expected to ship in May 2018.

All images courtesy Cell-Free Technology

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Habibou Kouyate, Stringer, Getty Images
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Play a Game to Help Scientists Defeat a Cancer-Causing Toxin
Habibou Kouyate, Stringer, Getty Images
Habibou Kouyate, Stringer, Getty Images

If you're used to fighting virtual zombies or flying spaceships on your computer, a new series of games available on Foldit may sound a little unconventional. The object of the Aflatoxin Challenge is to rearrange protein structures and create new enzymes. But its impact on the real world could make it the most important game you've ever played: The scientists behind it hope it will lead to a new way to fight one of the most ruthless causes of liver cancer.

As Fast Company reports, the citizen science project is a collaboration between Mars, Inc. and U.C. Davis, the University of Washington, the Partnership for Aflatoxin Control in Africa, and Thermo Fisher Scientific. The team's online puzzles, which debuted on Foldit earlier this month, invite the public to create a new enzyme capable of finding and destroying carcinogens known as aflatoxins.

Aflatoxins form when certain fungi grow on crops like corn, nuts, and grains. Developing countries often don't have the resources to detect it in food, leaving around 4.5 billion people vulnerable to it. When people do eat food with high aflatoxin levels unknowingly, they can contract liver cancer. Roughly a quarter of all liver cancer cases around the world can be traced back to aflatoxin exposure.

The toxin's connection to agriculture is why the food giant Mars is so interested in fighting it. By working on a way to stop aflatoxins on a molecular level, the company could prevent its spread more efficiently than they would with less direct methods like planting drought-resistant crops or removing mold by hand.

The easiest way for scientists to eradicate an aflatoxin before it causes real harm is by making an enzyme that does the work for them. With the Aflatoxin Challenge, the hope is that by manipulating protein structures, online players will come up with an enzyme that attacks aflatoxins at a susceptible portion of their molecular structure called a lactone ring. Destroying the lactone ring makes aflatoxin much less toxic and essentially safe to eat.

The University of Washington launched Foldit in 2008. Since then, the online puzzle platform has been used to study a wide range of diseases including AIDS and Chikungunya. Everyone is welcome to contribute to the Foldit's new aflatoxin project for the next several weeks or so, after which scientists will synthesize genes based on the most impressive results to be used in future studies.

[h/t Fast Company]

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