Does Drinking Alcohol Kill Brain Cells?

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Watch someone after they’ve had a few drinks, and you’ll find clear evidence that alcohol does something to their brain. They stumble, slur their words, lose control of their emotions, and forget things. 

Some people have tried to explain this behavior as the aftermath of cell death caused by alcohol. Often, it’s packaged as a neat factoid like “Three beers kill 10,000 brain cells.”

But is this true? No. But alcohol does damage some of your 86 billion brain cells, or neurons, which send electrical and chemical messages within the brain and between it and other parts of the body. 

Ethyl alcohol (the kind found in boozy beverages, also known as ethanol) can kill cells and microorganisms. That’s what makes it an effective antiseptic. Fortunately, when you drink alcoholic beverages, your body tries not to let all of that ethanol roam around unchecked. Enzymes in your liver convert it first info acetaldehyde (which is highly toxic) and then into acetate, which is broken down into water and carbon dioxide and eliminated by your body.

The liver can only work so fast, though, processing about 12 ounces of beer, 5 ounces of wine, or 1.5 ounces of distilled spirits per hour. If you’re knocking drinks back fast enough that your liver can’t keep up, the excess alcohol hangs out in the blood and travels through the body until it can be processed. 

When this alcohol reaches the brain, it doesn’t kill the cells. What it does is inhibit the communication between dendrites, or branching connections at the ends of neurons that send and receive information between neurons, in the cerebellum, a part of the brain involved in motor coordination. This poor communication results in some of the typical impairments of intoxication. 

Researchers at Washington University in St. Louis found that alcohol, even when applied directly to neurons, didn’t kill them. It just interfered with the way they transmit information. Specifically, the researchers showed that alcohol causes certain receptors on neurons to manufacture steroids that inhibit memory formation. 

Some alcoholics can experience neuron death as part of a brain disorder called Wernicke-Korsakoff syndrome. In these cases, the evidence again suggests that the disease and cell death aren’t caused by the alcohol itself, but a B1 (or thiamine) deficiency and general malnutrition that often go hand in hand with alcoholism. 

For moderate drinkers, a number of studies from the last 15 years suggest that, far from killing brain cells, a little tipple is actually associated with a reduced risk of cognitive decline and dementia. 

Why is Friday the 13th Considered Unlucky?

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Today, people around the globe will feel uneasy about getting out of bed, leaving their homes, or going about their normal daily routines, all because of a superstition. These unfortunate folks suffer from paraskavedekatriaphobia, a common neurosis familiar to us all: the fear of Friday the 13th. But just where did this superstitious association come from, and how did it catch on?

The truth is that no one is absolutely sure where the idea that Friday the 13th is unlucky originated. Donald Dossey, the founder of the Stress Management Center and Phobia Institute in Asheville, North Carolina, suspects the fear can be traced back to a Norse myth about 12 gods who had a dinner at Valhalla—the fabled hall where legendary Norse heroes feasted for eternity after they died—that was interrupted by a 13th guest, the evil and mischievous god Loki.

According to legend, Loki tricked Höðr (the blind god of winter and son of Odin, the supreme god in Norse mythology) into shooting his brother Baldr (the benevolent god of summer who was also a son of Odin) with a magical spear tipped with mistletoe—the only substance that could defeat him. Thus the number 13 was branded as unlucky because of the ominous period of mourning following the loss of such powerful gods by this unwanted 13th guest.

For whatever reason, among many cultures, the number 12 emerged throughout history as a "complete" number: There are 12 months in a year, 12 signs of the zodiac, 12 Gods of Olympus, 12 sons of Odin, 12 labors of Hercules, 12 Jyotirlingas or Hindu shrines where Shiva is worshipped, 12 successors of Muhammad in Shia Islam, and 12 tribes of Israel. In Christianity, Jesus was betrayed by one of his 12 Apostles—Judas—who was the 13th guest to arrive for the Last Supper. Surpassing the number 12 ostensibly unbalances the ideal nature of things; because it is seen as irregular and disrespectful of a sense of perfection, the number 13 bears the stigma of misfortune and bad luck we know today.

WHY FRIDAY?

Friday joins in the mix mostly because all of the early accounts of Jesus’s crucifixion agree that it took place on Friday—the standard day for crucifixions in Rome. As Chaucer noted in The Canterbury Tales, "And on a Friday fell all this mischance." Yet perpetuating Friday as an unlucky day in America came from the late 19th-century American tradition of holding all executions on Fridays; Friday the 13th became the unluckiest of days simply because it combined two distinct superstitions into one. According to the Oxford University Press Dictionary of Superstitions, the first reference to Friday the 13th itself wasn’t until 1913. (So despite actually occurring on Friday, October 13, 1307, the popular notion that the Friday the 13th stigma comes from the date on which the famed order of the Knights Templar were wiped out by King Philip of France is just a coincidence.)

The repercussions of these phobias reverberated through American culture, particularly in the 20th century. Most skyscrapers and hotels lack a 13th floor, which specifically comes from the tendency in the early 1900s for buildings in New York City to omit the unlucky number (though the Empire State Building has a 13th floor). Some street addresses also skip from 12 to 14, while airports may skip the 13th gate. Allegedly, the popular Friday the 13th films were so-named just to cash in on this menacing date recognition, not because the filmmakers actually believed the date to be unlucky.

So, is Friday the 13th actually unlucky? Despite centuries of superstitious behavior, it largely seems like psychological mumbo jumbo. One 1993 study seemed to reveal that, statistically speaking, Friday the 13th is unlucky, but the study's authors told LiveScience that though the data was accurate, "the paper was just a bit of fun and not to be taken seriously." Other studies have shown no correlation between things like increased accidents or injuries and Friday the 13th.

And Friday the 13th isn't a big deal in other cultures, which have their own unlucky days: Greeks and Spanish-speaking countries consider Tuesday the 13th to be the unluckiest day, while Italians steer clear of Friday the 17th. So today, try to rest a little easy—Friday the 13th may not be so unlucky after all.

Additional Source: 13: The Story of the World’s Most Popular Superstition.

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Does the Full Moon Really Make People Act Crazy?

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iStock.com/voraorn

Along with Mercury in retrograde, the full moon is a pretty popular scapegoat for bad luck and bizarre behavior. Encounter someone acting strangely? Blame it on the lunar phases! It's said that crime rates increase and emergency rooms are much busier during the full moon (though a 2004 study debunked this claim). Plus, there's that whole werewolf thing. Why would this be? The reasoning is that the moon, which affects the ocean's tides, probably exerts a similar effect on us, because the human body is made mostly of water.

This belief that the moon influences behavior is so widely held—reportedly, even 80 percent of nurses and 64 percent of doctors think it's true, according to a 1987 paper published in the Journal of Emergency Medicine [PDF]—that in 2012 a team of researchers at Université Laval's School of Psychology in Canada decided to find out if mental illness and the phases of the moon are linked [PDF].

To test the theory, the researchers evaluated 771 patients who visited emergency rooms at two hospitals in Montreal between March 2005 and April 2008. The patients chosen complained of chest pains, which doctors could not determine a medical cause for the pains. Many of the patients suffered from panic attacks, anxiety and mood disorders, or suicidal thoughts.

When the researchers compared the time of the visits to the phases of the moon, they found that there was no link between the incidence of psychological problems and the four lunar phases, with one exception: in the last lunar quarter, anxiety disorders were 32 percent less frequent. "This may be coincidental or due to factors we did not take into account," Dr. Geneviève Belleville, who directed the team of researchers, said. "But one thing is certain: we observed no full-moon or new-moon effect on psychological problems."

So rest easy (or maybe not): If people seem to act crazy during the full moon, their behavior is likely pretty similar during the rest of the lunar cycle as well.

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