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11 Items You'll No Longer Find in Medicine Cabinets

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Medicines and medical practices have come a long way in a relatively short time. Here are some items that have vanished from medicine cabinets in the last few decades.

1. Mercurochrome

Most folks under the age of 30 have never heard of this topical antiseptic. But many of us Boomers begged mom to daub our cuts and scrapes with the relatively painless Mercurochrome in lieu of that nasty stinging Iodine. Sure it stained your flesh pinkish-red, but you could probably wear that temporarily as a battle scar. The U.S. Food and Drug Administration put very strict limitations on the sale of Mercurochrome in 1998 and stated that it was no longer considered to be a GRAS (Generally Recognized As Safe) over-the-counter product. Many grandmothers scoffed, "Since when?! I used that stuff for years and none of my kids died!" But more scientific minds agreed that the ban was a wise and "about time!" decision, since the main active ingredient in Mercurochrome is mercury.

2. Iodine

Iodine burned like fire when applied to an open wound; this was mainly because the tincture sold for home use had an alcohol base. Many doctors today use a water-based iodine as an antiseptic, as it has one of the broadest germ-killing spectrums. The skull and crossbones on the label along with the word POISON in capital letters probably give a clue as to why this old school remedy is rarely found in home first aid kits anymore.

3. Mercury Thermometer


Before those convenient in-your-ear digital thermometers hit the market, we had to struggle to keep these heavy glass models under our tongues long enough for the mercury filling to register whether or not we were sick enough to stay home from school. My younger brother, Iron Jaws, bit through enough of these that Mom managed to collect a nice sized blob of mercury that she kept in a bottle for our amusement. Mercury thermometers are still available in the US (they've been banned throughout much of Europe and Asia), but the American Medical Association and the Environmental Protection Agency "strongly recommend" that alternative thermometers be used in the home.

4. Castor Oil

Once upon a time a bottle of vile-tasting castor oil was a staple in every medicine cabinet. For some reason, mothers in the 1920s and '30s used it as a cure-all for any sort of tummy ailment. In reality, the only condition castor oil is suitable to treat is constipation, and even in that case doctors tend to discourage its use, as the results are often unpredictable and can result in severe cramping and involuntary explosive bowel movements that last for hours.

5. TB Test


The skin test for tuberculosis was a common annual procedure for all elementary school children in the US during the 1940s, '50s, and '60s. The rate of infection decreased dramatically by the late 1970s, and universal TB testing gradually ceased. By the early 1990s, the American Academy of Pediatrics recommended testing for at-risk children (immigrants from Mexico, the Philippines, Vietnam, India, and China; kids exposed to IV drug users or adults with HIV) only. The benefits of targeted testing are proven, but implementing a procedure is difficult to do without stigmatizing the affected children, so in some school districts the program is currently in political limbo.

6. Disclosure Tablets


It used to be that once a year the school nurse, usually accompanied by a representative from Colgate or Crest, presented everyone in class with a packet containing a free toothbrush, a tiny tube of toothpaste, and two small red pills. The pills were disclosure tablets, and their purpose was to indicate the disgusting areas of your mouth where plaque was collecting and you needed to step up your brushing routine lest you end up with dentures in high school. The dental kits are rarely given away as a matter of routine today; thanks to today's litigious society, you usually have to ask your dentist or pharmacist for the tablets. That way they can ask all the proper questions ahead of time to make sure you (or your child) aren't allergic to anything in them or whether they violate your dietary restrictions (guess there weren't that many vegan kids back in the 1960s).

7. Fluoride


How many of you gagged just looking at that photo? For kids whose families were unable to afford to go to a dentist, public schools often offered a free fluoride treatment once per year. And even though we saw our dentist regularly, my mom couldn't pass up a freebie and always signed us up for the torture procedure. The fluoride was thick and syrupy and tasted terrible no matter what fun new flavor (like "bubblegum") they attempted to disguise it with. Luckily fluoridated water, toothpastes, rinses, and the like have virtually eliminated the need for additional special fluoride treatments.

8. Eye Patch for Amblyopia


Years ago the most popular treatment for "lazy eye" was a pirate-style eye patch worn over the good eye. Thanks to new treatments like specialized lenses and eye drops, patching is used only in a small percentage of cases these days. And, when patching the amblyopic eye is deemed necessary, doctors have discovered that an adhesive patch worn for a few hours daily is far more effective than the Moshe Dayan model.

9. Nurse's Cap

Remember how the mere sight of the nurse entering the examining room in her starched white uniform with the cap perched atop her head was enough to make you break into a flop sweat as a kid? Forget about "white coat syndrome," that severe uniform made every woman look like Nurse Ratched and sent many a patient into panic mode. Nurses ditched the white dresses and pantyhose in the 1980s in favor of colorful and whimsical scrubs, which were both more practical and comfortable for the wearer and more relaxing for the patient. And while the cap was the iconic symbol of nursing (nursing students were presented their caps with great ceremony upon graduation), it was also extremely unhygienic; even with multiple bobby pins, the hat rarely stayed in place, forcing the wearer to constantly fuss with it, touching her hair and contaminating her hands. Today's nursing school graduates receive pins instead of caps.

10. Head Mirror

Old-time movie and TV doctors always wore their head mirrors over their foreheads, like a shiny bullseye. In practice, however, the mirror (which was invented in the mid-1800s) was worn over one eye so that the doctor could peep through the tiny hole in the middle. The rest of the disc reflected an overhead light (or even the sunlight) onto the area of the patient the doctor was examining. Positioning the mirror just so literally took hours of practice, and most doctors today use a battery-operated head light instead. Some otorhinolaryngologists still prefer the mirror, though, believing that it provides the best light for indirect laryngeal examination.

11. Iron Lung


Dr. Philip Drinker of the Harvard School of Public Health developed the first "thoracic cage" that used vacuum cleaner blowers to alternate between atmospheric and sub-atmospheric pressure to force a patient to breathe. The machine, known as a Drinker Respirator, was originally intended as a pediatric-ward device to assist premature babies born with under-developed lungs. But when the dreaded disease known as polio began to spread in the United States, doctors found a second use for the device. Polio frequently paralyzed patients' diaphragms, rendering them unable to breathe on their own. The Warren Collins Corporation fine-tuned Drinker's design and mass-produced a similar device at a more affordable price; it was dubbed the Iron Lung. In the early 1950s, most hospitals had wards filled with iron lungs, and many homes had a polio patient encased in one as well. Today's patients who are unable to breathe on their own are intubated with positive pressure ventilators, as opposed to the negative pressure utilized by the iron lung of yesteryear.
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What home remedies do you remember grandma or mom using on you when you were a kid? What medical device that scared you to death has been replaced by a kinder, gentler gadget? Share both your horror stories and warm fuzzies!

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Big Questions
What Is the Difference Between Generic and Name Brand Ibuprofen?
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What is the difference between generic ibuprofen vs. name brands?

Yali Friedman:

I just published a paper that answers this question: Are Generic Drugs Less Safe than their Branded Equivalents?

Here’s the tl;dr version:

Generic drugs are versions of drugs made by companies other than the company which originally developed the drug.

To gain FDA approval, a generic drug must:

  • Contain the same active ingredients as the innovator drug (inactive ingredients may vary)
  • Be identical in strength, dosage form, and route of administration
  • Have the same use indications
  • Be bioequivalent
  • Meet the same batch requirements for identity, strength, purity, and quality
  • Be manufactured under the same strict standards of FDA's good manufacturing practice regulations required for innovator products

I hope you found this answer useful. Feel free to reach out at www.thinkbiotech.com. For more on generic drugs, you can see our resources and whitepapers at Pharmaceutical strategic guidance and whitepapers

This post originally appeared on Quora. Click here to view.

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science
2017 Ig Nobel Prizes Celebrate Research on How Crocodiles Affect Gambling and Other Odd Studies
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The Ig Nobel Prizes are back, and this year's winning selection of odd scientific research topics is as weird as ever. As The Guardian reports, the 27th annual awards of highly improbable studies "that first make people laugh, then make them think" were handed out on September 14 at a theater at Harvard University. The awards, sponsored by the Annals of Improbable Research, honor research you never would have thought someone would take the time (or the funding) to study, much less would be published.

The 2017 highlights include a study on whether cats can be both a liquid and a solid at the same time and one on whether the presence of a live crocodile can impact the behavior of gamblers. Below, we present the winners from each of the 10 categories, each weirder and more delightful than the last.

PHYSICS

"For using fluid dynamics to probe the question 'Can a Cat Be Both a Solid and a Liquid?'"

Winner: Marc-Antoine Fardin

Study: "On the Rheology of Cats," published in Rheology Bulletin [PDF]

ECONOMICS

"For their experiments to see how contact with a live crocodile affects a person's willingness to gamble."

Winners: Matthew J. Rockloff and Nancy Greer

Study: "Never Smile at a Crocodile: Betting on Electronic Gaming Machines is Intensified by Reptile-Induced Arousal," published in the Journal of Gambling Studies

ANATOMY

"For his medical research study 'Why Do Old Men Have Big Ears?'"

Winner: James A. Heathcote

Study: "Why Do Old Men Have Big Ears?" published in the BMJ

BIOLOGY

"For their discovery of a female penis, and a male vagina, in a cave insect."

Winners: Kazunori Yoshizawa, Rodrigo L. Ferreira, Yoshitaka Kamimura, and Charles Lienhard (who delivered their acceptance speech via video from inside a cave)

Study: "Female Penis, Male Vagina and Their Correlated Evolution in a Cave Insect," published in Current Biology

FLUID DYNAMICS

"For studying the dynamics of liquid-sloshing, to learn what happens when a person walks backwards while carrying a cup of coffee."

Winner: Jiwon Han

Study: "A Study on the Coffee Spilling Phenomena in the Low Impulse Regime," published in Achievements in the Life Sciences

NUTRITION

"For the first scientific report of human blood in the diet of the hairy-legged vampire bat."

Winners: Fernanda Ito, Enrico Bernard, and Rodrigo A. Torres

Study: "What is for Dinner? First Report of Human Blood in the Diet of the Hairy-Legged Vampire Bat Diphylla ecaudata," published in Acta Chiropterologica

MEDICINE

"For using advanced brain-scanning technology to measure the extent to which some people are disgusted by cheese."

Winners: Jean-Pierre Royet, David Meunier, Nicolas Torquet, Anne-Marie Mouly, and Tao Jiang

Study: "The Neural Bases of Disgust for Cheese: An fMRI Study," published in Frontiers in Human Neuroscience

COGNITION

"For demonstrating that many identical twins cannot tell themselves apart visually."

Winners: Matteo Martini, Ilaria Bufalari, Maria Antonietta Stazi, and Salvatore Maria Aglioti

Study: "Is That Me or My Twin? Lack of Self-Face Recognition Advantage in Identical Twins," published in PLOS One

OBSTETRICS

"For showing that a developing human fetus responds more strongly to music that is played electromechanically inside the mother's vagina than to music that is played electromechanically on the mother's belly."

Winners: Marisa López-Teijón, Álex García-Faura, Alberto Prats-Galino, and Luis Pallarés Aniorte

Study: "Fetal Facial Expression in Response to Intravaginal Music Emission,” published in Ultrasound

PEACE PRIZE

"For demonstrating that regular playing of a didgeridoo is an effective treatment for obstructive sleep apnoea and snoring."

Winners: Milo A. Puhan, Alex Suarez, Christian Lo Cascio, Alfred Zahn, Markus Heitz, and Otto Braendli

Study: "Didgeridoo Playing as Alternative Treatment for Obstructive Sleep Apnoea Syndrome: Randomised Controlled Trial," published by the BMJ

Congratulations, all.

[h/t The Guardian]

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