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Why Do Paper Cuts Hurt So Much?

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Paper cut image via Shutterstock

There are a couple things at play here, some involving the paper, some involving your skin.

For one thing, what part of your body comes in contact with paper the most? Right, the majority of paper cuts happen on the fingers and hands. Your hands are pretty complex sensory instruments, and they’re absolutely jam-packed with nerve fibers called nociceptors. These guys sense temperature, pressure and pain, and there are more of them per square inch in your hands and fingers than most other parts of your body. Injuries there are noticed much more than similar injuries elsewhere. The same small paper cut on a less nerve-dense area, such as, say, your leg, won’t send nearly as many pain signals to your brain.

To make matters worse, it’s not like you can just not use your hands for a few days after every paper cut. You’ve got stuff to touch and things to pick up, so while the cut heals, the skin keeps moving and the edges of the wound tend to get pulled apart, delaying healing and prolonging the pain.

All right, sure, your hands are very sensitive, but then why do paper cuts hurt more than some cuts made by other objects, like knives? Well, the blade of even a fairly dull knife tends to be more straight and sharp than the dull and flexible edge of a piece of paper. When a knife cuts your skin, it leaves a relatively clean cut compared to paper, which will flex a little and do more microscopic damage to the skin. Paper also makes a more shallow wound than most other cutting injuries. A shallow cut on the surface might only bleed a little, or not at all. Without a blood clot to protect them, the nerves around the cut are exposed to air and other irritants, which can make the pain more noticeable and longer lasting.

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Big Questions
What Is the Difference Between Generic and Name Brand Ibuprofen?
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What is the difference between generic ibuprofen vs. name brands?

Yali Friedman:

I just published a paper that answers this question: Are Generic Drugs Less Safe than their Branded Equivalents?

Here’s the tl;dr version:

Generic drugs are versions of drugs made by companies other than the company which originally developed the drug.

To gain FDA approval, a generic drug must:

  • Contain the same active ingredients as the innovator drug (inactive ingredients may vary)
  • Be identical in strength, dosage form, and route of administration
  • Have the same use indications
  • Be bioequivalent
  • Meet the same batch requirements for identity, strength, purity, and quality
  • Be manufactured under the same strict standards of FDA's good manufacturing practice regulations required for innovator products

I hope you found this answer useful. Feel free to reach out at www.thinkbiotech.com. For more on generic drugs, you can see our resources and whitepapers at Pharmaceutical strategic guidance and whitepapers

This post originally appeared on Quora. Click here to view.

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Big Questions
Do Cats Fart?
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Certain philosophical questions can invade even the most disciplined of minds. Do aliens exist? Can a soul ever be measured? Do cats fart?

While the latter may not have weighed heavily on some of history’s great brains, it’s certainly no less deserving of an answer. And in contrast to existential queries, there’s a pretty definitive response: Yes, they do. We just don’t really hear it.

According to veterinarians who have realized their job sometimes involves answering inane questions about animals passing gas, cats have all the biological hardware necessary for a fart: a gastrointestinal system and an anus. When excess air builds up as a result of gulping breaths or gut bacteria, a pungent cloud will be released from their rear ends. Smell a kitten’s butt sometime and you’ll walk away convinced that cats fart.

The discretion, or lack of audible farts, is probably due to the fact that cats don’t gulp their food like dogs do, leading to less air accumulating in their digestive tract.

So, yes, cats do fart. But they do it with the same grace and stealth they use to approach everything else. Think about that the next time you blame the dog.

Have you got a Big Question you'd like us to answer? If so, let us know by emailing us at bigquestions@mentalfloss.com.

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