What Causes Hiccups?

iStock/damircudic
iStock/damircudic

The cause of hiccups depends on whom you ask. The ancient Greek physician Galen thought hiccups were violent emotions erupting from the body, while others thought they were a sign of liver inflammation. Today, evidence points to spasms in the diaphragm, the large muscle between the chest and abdomen that aids airflow during breathing. This involuntary contraction can be brought on by a number of things that might irritate the nerves that control the movement of the muscle. A full stomach, heavy boozing, rapid shifts in temperature either inside or outside of the stomach, and certain emotions like shock or excitement are all common culprits.

No matter the cause, the result is the same: The diaphragm spasms and causes us to take a quick breath. The sudden rush of air causes the epiglottis (the flap that protects the space between the vocal cords) to shut and interrupt the breath, which makes the familiar "hic" sound.

WHAT CURES THEM?

The best cure for hiccups also depends on the person you ask. Almost all cures are based on one of two principles: One type works its magic by overwhelming the vagus nerve with another sensation. The vagus nerve is a cranial nerve that innervates the stomach and conveys sensory information about the body's organs to the brain. When distracted by overwhelming information of another sort, it basically tells the brain that something more important has come up and the hiccuping should probably be stopped (vagus nerve stimulation is also used to control seizures in epileptics and treat drug-resistant cases of clinical depression). The other method for curing hiccups is to interfere with the breathing, increasing the amount of carbon dioxide in the blood, and causing the body to focus on getting rid of the of the CO2 and not making hiccups.

Swallowing a spoonful of sugar is probably the most commonly prescribed hiccup cure and falls into the first category. A teaspoon of sugar is usually enough to stimulate the vagus nerve and make the body forget all about the hiccups. Even ardent supporters of the sugar cure disagree if the sugar should be taken dry or washed down with water, though.

If this home remedy doesn't work, and your hiccups are both severe and persistent, you may need to bring out the big guns. For chronic cases like this, doctors sometimes use a cocktail of Reglan (a gastrointestinal stimulant) and Thorazine (an anti-psychotic with sedative properties) to quiet things down. In some cases that resist these drugs, Kemstro, an anti-spasmodic, is also used. Other doctors have used vagus nerve stimulators implanted in the upper chest of patients. The pacemaker-like devices send rhythmic bursts of electricity through the vagus nerve to the brain to keep the hiccup cycle in check.

Many people prefer home remedies to battle their hiccups, which may include holding your breath, gargling ice water, or breathing into a paper bag. While the same people will swear by the treatment they've been using all these years, there's no firm scientific consensus that any of them actually work. But if it helps you, isn't that all that matters?

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An earlier version of this article appeared in 2012.

What Is the Shelf Life of Donated Eyes?

iStock.com/Pedro_Turrini
iStock.com/Pedro_Turrini

Zoe-Anne Barcellos:

I can only answer for cornea and eye donation.

The FDA does all oversight (no pun intended) of organ disposition.

The main organs—heart, liver, pancreas, lungs, etc.—are transplanted within hours. They are just not viable if they are not being perfused constantly.

The other tissues—like bone, skin, tendons, etc.—do not need to be transplanted immediately. But I am not sure on the regulations of when they need to be transplanted.

With the eyes, there are four tissues that can be recovered.

We recover whole eyes for research and education purposes. These usually go much faster, but we can hold them up to a year.

Conjunctiva can also be recovered; conjunctiva is a clear covering over most of the eye (it is what gets irritated when you have pink eye). I have been working as a recovery tech for five years, and our office has not had a request for "conj" in all that time. I believe it is mostly used for research, but I could be wrong.

Sclera is the white area of your eye. It is fairly thick and flexible. If you have ever touched a reptile egg, that is what it reminds me of. We recover sclera for transplant. They use it for several things, but mainly to patch punctures. Similar to if you pop the inner tube of your bike and repair it. Sclera can also be used to repair ear drums. We can hold on to this for up to a year.

The main thing we recover is corneas. In the U.S., we must transplant these within seven days of recovery. (Recovery is usually within hours of death, but we can push it up to 20 hours after if needed.) Sometimes we have more corneas than we need, and then they are shipped overseas and transplanted up to 14 days after recovery. There is no real different outcome with the later transplant time, but the FDA in the U.S. made the rules. (You can sign up to be an organ, tissue, and eye donor here.)

This post originally appeared on Quora. Click here to view.

Why Are There No Snakes in Ireland?

iStock
iStock

Legend tells of St. Patrick using the power of his faith to drive all of Ireland’s snakes into the sea. It’s an impressive image, but there’s no way it could have happened.

There never were any snakes in Ireland, partly for the same reason that there are no snakes in Hawaii, Iceland, New Zealand, Greenland, or Antarctica: the Emerald Isle is, well, an island.

Eightofnine via Wikimedia Commons // Public Domain

Once upon a time, Ireland was connected to a larger landmass. But that time was an ice age that kept the land far too chilly for cold-blooded reptiles. As the ice age ended around 10,000 years ago, glaciers melted, pouring even more cold water into the now-impassable expanse between Ireland and its neighbors.

Other animals, like wild boars, lynx, and brown bears, managed to make it across—as did a single reptile: the common lizard. Snakes, however, missed their chance.

The country’s serpent-free reputation has, somewhat perversely, turned snake ownership into a status symbol. There have been numerous reports of large pet snakes escaping or being released. As of yet, no species has managed to take hold in the wild—a small miracle in itself.

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