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A Brief History of Flintstones Vitamins

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The Flintstones has been off the air and in syndication since 1966. But Flintstones Vitamins remain on the shelves and in homes.

Meet the Flintstones

The Flintstones were, just like the theme song claimed, a modern Stone Age family.

Fred and Wilma Flintstone and their best friends and next-door neighbors, Barney and Betty Rubble, lived in working class suburban splendor in the city of Bedrock. Wilma was the consummate housewife, rocking “pearls” with her cavewoman-style dress and using a baby elephant as a vacuum cleaner; Fred, her lovable lug counterpart, worked at a local quarry and enjoyed bowling. A baby dinosaur, Dino, was the family dog and a sabertooth tiger, Baby Puss, the family cat. Later, little Pebbles Flintstone and Bamm-Bamm Rubble joined the cast.

But despite the fact that it was a cartoon and featured more rock-based puns than your average adult-oriented sitcom, The Flintstones was not originally for kids. In fact, when it premiered on ABC in 1960, it took the Friday night, 8:30 to 9 pm slot, and was meant to be a kind of Stone Age Honeymooners. And it was popular — but mostly with teenagers. This, according to the Museum of Broadcast Communication, heralded a shift away from live-action children’s programming towards animation.

The Merchandising

The show’s popularity with kids logically gave rise to a vast collection of Flintstones merchandising — alarm clocks, cookie jars, trading cars, bubble gum, toys, and, of course, vitamins.

Though they’ve obviously been around forever, vitamins, meaning a group of organic substances necessary to the function of a normal metabolism, were “discovered” by science in the 18th and 19th centuries. By the middle of the 20th century, however, vitamins had been removed from scientific study and placed squarely in the realm of commerce. Vitamins in pill form, a 20th century invention, were peddled not by medical personnel, but by retailers, such as grocery giant Kroger.

Vitamins were also high profit items, with a market ready for diversification. In 1960, the vitamin giant Miles Laboratory, owners of the One-a-Day label, developed Chocks, the first chewable vitamin aimed at children. And, even as doctors, Food and Drug Administration officials, and scientists tussled over the alleged medical benefits of vitamins, Miles was making a mint off its candy-like chewables.

With a hold on the children’s vitamin market, it wasn’t surprising, therefore, that the company would choose to pair up with one of the most popular children’s shows at the time. In 1968, Miles paired up with the modern Stone Age family, producing chewy vitamins in a variety of flavors and in the shapes of the characters.

The Flintstones were a solid, trustworthy lot who kids believed in and the vitamins were pretty much an instant hit. Miles Laboratory, which later introduced Bugs Bunny vitamins as well, dominated the children’s vitamin category for years, until it was acquired by Bayer as a subsidiary in 1979. Though Miles was no more, Flintstones Vitamins remained a market leader — and still are, though new characters like SpongeBob SquarePants and crew are starting to crowd in on the action. Nowadays, there are seven varieties of the flavor and vitamin-packed cartoon shapes: Flintstones Sour Gummies, Flintstones Gummies, Flintstones Complete with Choline (Choline, a nutrient found in breast milk and, of course, cauliflower, is good for brain development), Flintstones Plus Extra C, Flintstones Plus Calcium, Flintstones Plus Iron, and My First Flintstones.

Perhaps some of the explanation for the Flintstone Vitamins continued success is in their nostalgia for the generations of children who grew up with them — and who are now parents themselves. There’s even a Facebook group for those who ate the vitamins as a kid. And then there’s that jingle — “Ten million strong and growing!” — which, incidentally, was composed by Martin O’Donnell, the same guy who composed the music for the intensely popular Halo video game series.

Betty’s Not a Vitamin

But there was one great injustice underlying the Flintstones Vitamin empire: Nearly all the Flintstones characters — including the bizarre Martian character, Great Gazoo — all at one time had fruity, chalky likenesses. All, except Betty. Poor Betty, destined to always play second fiddle to Wilma, didn’t even warrant her own vitamin.

There were (at least) two possible reasons why Betty didn’t have her own vitamin: First, manufacturers claimed that Betty’s waist was too thin and kept breaking during production. Second, Betty was virtually indistinguishable from Wilma.

Though there was a small Betty for vitamin movement, including an Atlanta rock band that called itself Betty’s Not a Vitamin, it wasn’t until actress and comedienne Rosie O’Donnell, who played Betty in the 1994 live action film, brought Betty’s plight to the attention of the nation that anything was really done about it. O’Donnell, during a television interview about the film, complained that all the other characters were represented, but not Betty. A savvy marketing agency seized the opportunity to involve the consumer in the direction of the brand and launched a nationwide campaign to determine Betty’s fate. The agency set up prehistoric style voting booths in regional shopping malls across the country, as well as a 1-800 number, to allow consumers to decide whether Betty should be let in the club.

The public didn’t let her down. More than 3,000 kids and their mothers voted in person and more than 17,000 calls were logged, with 91 percent in favor of bringing in Betty. She became a character in December 1995, replacing the Flintmobile.

Notably, Betty’s Not a Vitamin was named one of the 100 best band names by Paste magazine.

Yabba Dabba Doo!

And finally, vitamins weren’t the only things that the modern Stone Age family hawked. In fact, one of the show’s original sponsors was Winston cigarettes: Fred and Barney were Winston men, all the way. One early cartoon featured Fred and Barney taking a “Winston break,” because “Winston tastes good, like a cigarette should.”

While the Winston ads weren’t so much a problem, people later objected to the Flintstones pushing drugs, even if they were multivitamins. The concern there was that commercials for Flintstone Vitamins were misleading in terms of the actual health benefits of the vitamins. Miles Laboratory, in the early 1970s, was forced by FDA and Federal Trade Commission scrutiny to pull away from advertising during children’s programming, such as the Saturday morning cartoons hours.

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Health
New Test Can Differentiate Between Tick-borne Illnesses
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Time is of the essence in diagnosing and treating Lyme disease and other tick-borne illnesses. Fortunately, one new test may be able to help. A report on the test was published in the journal Science Translational Medicine.

Ticks and the diseases they carry are on the rise. One 2016 study found deer ticks—the species that carries Lyme disease—in more than half of the counties in the United States.

The two most common tick-borne illnesses in the U.S. are Lyme disease and southern tick-associated rash illness (STARI). Although their initial symptoms can be the same, they’re caused by different pathogens; Lyme disease comes from infection with the bacterium Borrelia burgdorferi. We don’t know what causes STARI.

"It is extremely important to be able to tell a patient they have Lyme disease as early as possible so they can be treated as quickly as possible," microbiologist and first author Claudia Molins of the CDC said in a statement. "Most Lyme disease infections are successfully treated with a two- to three-week course of oral antibiotics." Infections that aren't treated can lead to fevers, facial paralysis, heart palpitations, nerve pain, arthritis, short-term memory loss, and inflammation of the brain and spinal cord.

But to date, scientists have yet to create an accurate, consistent early test for Lyme disease, which means people must often wait until they’re very ill. And it’s hard to test for the STARI pathogen when we don’t know what it is.

One team of researchers led by experts at Colorado State University was determined to find a better way. They realized that, rather than looking for pathogens, they could look at the way a person’s body responded to the pathogens.

They analyzed blood samples from patients with both early-stage Lyme disease and STARI. Their results showed that while all patients’ immune systems had mounted a response, the nature of that response was different.

"We have found that all of these infections and diseases are associated with an inflammatory response, but the alteration of the immune response, and the metabolic profiles aren't all the same," senior author John Belisle of CSU said.

Two distinct profiles emerged. The team had found physical evidence, or biomarkers, for each illness: a way to tell one disease from another.

Belisle notes that there’s still plenty of work to do.

"The focus of our efforts is to develop a test that has a much greater sensitivity, and maintains that same level of specificity," Belisle said. "We don't want people to receive unnecessary treatment if they don't have Lyme disease, but we want to identify those who have the disease as quickly as possible."

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The Body
11 Interesting Facts About Lymph Nodes

The human body is an amazing thing. For each one of us, it's the most intimate object we know. And yet most of us don't know enough about it: its features, functions, quirks, and mysteries. Our series The Body explores human anatomy, part by part. Think of it as a mini digital encyclopedia with a dose of wow.

The lymphatic system is a crucial part of your body's ability to fight off infection and viruses. It's a key player in the immune system that functions by circulating lymphatic fluid through a series of lymph vessels all throughout your body. This fluid gathers up anything foreign, such as viruses and bacteria from your body tissues and flushes them to your lymph nodes, where immune cells attack whatever isn't helping your body. 

Mental Floss spoke to Adriana Medina, an internal medicine doctor with a specialty in hematology and oncology at the Alvin and Lois Lapidus Cancer Institute at Sinai Hospital in Baltimore, Maryland, about these important tissues. 

1. THERE ARE HUNDREDS OF NODES.

They're about size and shape of a pea, and hundreds of them are scattered all throughout the body. In order to fight many little pathogens and clear out unhelpful debris, your body needs a lot of nodes to rally to these causes, according to Medina. 

2. LYMPH NODES ARE HOME TO IMPORTANT IMMUNE CELLS.

"The lymph nodes are in charge of harboring lymphocytes," says Medina. Your body makes two main types of these immune cells, B-lymphocytes and T-lymphocytes (or B- and T-cells), which are crucial to your body's ability to fight off infections of all kinds. There are many sub-classes of the T-cells because "they are very important to attack infection," says Medina.

3. LYMPHOCYTES ESCORT FOREIGN INVADERS OUT.

When your lymph nodes receive some sort of foreign debris they recognize isn't ours, Medina says, "the B-lymphocytes are in charge of making antibodies." These antibodies "leave with the toxic substance," and signal other immune cells to come in and attack the cells.

4. WHERE DO ALL THE TOXINS GO?

Once the lymphatic fluid has grabbed up its targets, most of it returns to your blood stream, Medina explains, which is why it's so important for lymph cells to do their job: kill what aims to harm you before it gets flushed back into your system.

5. THERE ARE MANY CAUSES OF SWOLLEN LYMPH NODES.

When your immune system senses a foreign invader, be it a virus, bacteria, vaccine, or even some medications, it preps the lymph nodes to make antibodies and lymphocytes to fight off the offender. This also increases the amount of lymphatic fluid in the node, which can make it swollen and tender. Most of the time swollen lymph nodes are not a big cause for concern.

6. A HARD, RUBBERY LYMPH NODE IS A PROBLEM.

A lymph node that is harder rather than soft and persists for several weeks is worth a doctor visit. While lymph nodes can be tender or swollen and mobile when infected, "when there is a [cancerous] malignance…they're hard, rubbery, they don't move, and they don't go away. The lymph nodes are always telling us something."

7. YOU ARE THE PUMP FOR YOUR LYMPHATIC SYSTEM.

Unlike your blood, which has the heart to pump it through your body, your lymphatic fluid doesn't have a pump. Instead, it relies upon gravity and pressure, which you create when you move around, as well as light massage.

8. WHERE YOU FIND VEINS, YOU FIND LYMPHATIC VESSELS.

The lymphatic system and the circulatory system are separate systems, but connected, running in tandem like underground networks of streams. "Lymphatic vessels are distributed along the body wherever we have arteries [or] veins," says Medina.

9. YOUR LYMPH NODES AND YOUR SPLEEN WORK TOGETHER.

"The spleen is like one big lymph node," Medina says of the organ that lives between your stomach and diaphragm. "The spleen is able to produce additional blood cells in case we need it to." Additionally, she explains, many toxic substances are filtrated through the spleen. However, if something happens to your spleen and it needs to be removed, you can live without it; you just may become more prone to infection and require more vaccinations to protect you against aggressive viruses.

10. STAGES OF CANCER ARE DETERMINED BY THE NUMBER OF AFFECTED LYMPH NODES.

The easiest cancers to treat are those that remain in the tissue where they first occur. However, in metastatic cancers, cancer cells migrate to the lymph nodes, which can cause cancer to spread. "When the cancer is detected in lymph nodes, we have to try to find out how many lymph nodes are involved," Medina says. "Lymph node involvements [determines] the prognosis of the cancer." When lymph node involvement occurs, "the treatment has to be more aggressive," she says, often adding radiation to a regime of chemotherapy and other drugs.

11. RESEARCHERS ARE TURNING THE BODY'S OWN LYMPHOCYTES INTO CANCER FIGHTING TREATMENTS.

Breakthroughs in immunotherapy known as Car T-cell therapy turn the body's own immune system into a weapon against cancer by engineering patients' own immune cells to recognize and attack their tumors, according to the National Cancer Institute. "What's happening—it's just beautiful—is that [researchers] are using B-lymphocytes to fight not only breast cancer, but leukemia and lymphomas," Medina explains. "The results are so good and encouraging, changing chances of survival."

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