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How Scurvy Was Cured, then the Cure Was Lost

Yes, this really happened: scurvy was "cured" as early as 1497, when Vasco de Gama's crew discovered the power of citrus...but this cure was repeatedly lost, forgotten, rediscovered, misconstrued, confused, and just generally messed around with for hundreds of years, despite being a leading killer of seafarers and other explorers. By the 1870s the "citrus cure" was discredited, and for nearly sixty years, scurvy -- despite being cured, with scientific research to back it up -- continued killing people, including men on Scott's 1911 expedition to the South Pole. This went on until vitamin C was finally isolated in 1932 during research on guinea pigs. Self-described painter/computer guy Maciej Ceglowski gives us the absurdly fascinating story of scurvy -- a bizarre tale of science gone wrong, and a really good explanation of why you should eat a bit of citrus once in a while. (I would argue from this piece alone that Ceglowski needs to add "science journalist" to his title.)

Now, I had been taught in school that scurvy had been conquered in 1747, when the Scottish physician James Lind proved in one of the first controlled medical experiments that citrus fruits were an effective cure for the disease. From that point on, we were told, the Royal Navy had required a daily dose of lime juice to be mixed in with sailors' grog, and scurvy ceased to be a problem on long ocean voyages.

But here was a Royal Navy surgeon in 1911 apparently ignorant of what caused the disease, or how to cure it. Somehow a highly-trained group of scientists at the start of the 20th century knew less about scurvy than the average sea captain in Napoleonic times. [Robert Falcon] Scott left a [South Pole] base abundantly stocked with fresh meat, fruits, apples, and lime juice, and headed out on the ice for five months with no protection against scurvy, all the while confident he was not at risk. What happened?

... In the second half of the nineteenth century, the cure for scurvy was lost. The story of how this happened is a striking demonstration of the problem of induction, and how progress in one field of study can lead to unintended steps backward in another.

Read the rest for a highly readable, thoroughly researched history of scurvy and its treatment.

See also: our Scurvy T-Shirt ("When Life Gives You Scurvy, Make Lemonade").

(Story via Waxy.org.)

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science
What Pop Culture Gets Wrong About Dissociative Identity Disorder
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From the characters in Fight Club to Dr. Jekyll and Mr. Hyde, popular culture is filled with "split" personalities. These dramatic figures might be entertaining, but they're rarely (if ever) scientifically accurate, SciShow Psych's Hank Green explains in the channel's latest video. Most representations contribute to a collective misunderstanding of dissociative identity disorder, or DID, which was once known as multiple personality disorder.

Experts often disagree about DID's diagnostic criteria, what causes it, and in some cases, whether it exists at all. Many, however, agree that people with DID don't have multiple figures living inside their heads, all clamoring to take over their body at a moment's notice. Those with DID do have fragmented personalities, which can cause lapses of memory, psychological distress, and impaired daily function, among other side effects.

Learn more about DID (and what the media gets wrong about mental illness) by watching the video below.

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History
Scientists Reveal Long-Hidden Text in Alexander Hamilton Letter
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Age, deterioration, and water damage are just a few of the reasons historians can be short on information that was once readily available on paper. Sometimes, it’s simply a case of missing pages. Other times, researchers can see “lost” text right under their noses.

One example: a letter written by Alexander Hamilton to his future wife, Elizabeth Schuyler, on September 6, 1780. On the surface, it looked very much like a rant about a Revolutionary War skirmish in Camden, South Carolina. But Hamilton scholars were excited by the 14 lines of writing in the first paragraph that had been crossed out. If they could be read, they might reveal some new dimension to one of the better-known Founding Fathers.

Using the practice of multispectral imaging—sometimes called hyperspectral imaging—conservationists at the Library of Congress were recently able to shine a new light on what someone had attempted to scrub out. In multispectral imaging, different wavelengths of light are “bounced” off the paper to reveal (or hide) different ink pigments. By examining a document through these different wavelengths, investigators can tune in to faded or obscured handwriting and make it visible to the naked eye.

A hyperspectral image of Alexander Hamilton's handwriting
Hyperspectral imaging of Hamilton's handwriting, from being obscured (top) to isolated and revealed (bottom).
Library of Congress

The text revealed a more emotional and romantic side to Hamilton, who had used the lines to woo Elizabeth. Technicians uncovered most of what he had written, with words in brackets still obscured and inferred:

Do you know my sensations when I see the
sweet characters from your hand? Yes you do,
by comparing [them] with your [own]
for my Betsey [loves] me and is [acquainted]
with all the joys of fondness. [Would] you
[exchange] them my dear for any other worthy
blessings? Is there any thing you would put
in competition[,] with one glowing [kiss] of
[unreadable], anticipate the delights we [unreadable]
in the unrestrained intercourses of wedded love,
and bet your heart joins mine in [fervent]
[wishes] to heaven that [all obstacles] and [interruptions]
May [be] speedily [removed].

Hamilton and Elizabeth Schuyler married on December 14, 1780. So why did Hamilton try and hide such romantic words during or after their courtship? He probably didn’t. Historians believe that his son, John Church Hamilton, crossed them out before publishing the letter as a part of a book of his father’s correspondence. He may have considered the passage a little too sexy for mass consumption.

[h/t Library of Congress]

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