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Syphilis: One of Five Infamous Epidemics We Hope We Never See

I first approached Jason and Mangesh because I wanted to write an article about rare skin diseases. After they finished retching, they said "No, thank you," but invited me to blog on less gruesome forms of weird science. You'll find a smorgasbord of such topics here in the weeks to come, including installments on food science, famous poisons and home inventions. Besides an abiding passion for medical trivia, I'm driven by a sense of wonder at the body, in sickness and in health. I hope you'll weigh in on what else you'd like to read. We begin today with a study of Syphilis, one of Five Infamous Epidemics We Hope We Never See.

A POX UPON YOU: SYPHILIS
alcapone.jpg "¢ There are popular theories that many famous people suffered syphilis, including Shakespeare, Beethoven, Lincoln, Nietzsche, Lenin, and Hitler, but the evidence is circumstantial in most of these cases. But Al Capone did have syphilis, a doozy of a case, and it got bad while he was in prison. By 1938, the Alcatraz inmate showed many of the classic symptoms: skin lesions, dementia, hallucinations, difficulty standing, seizures, and personality changes.

"¢ The conventional theory on syphilis is that Christopher Columbus and his crew brought it to Europe after sleeping with Native American women in the New World. Wherever it came from, syphilis rocked Europe. By 1700, a quarter of its population had "the great pox."

"¢ Syphilis has a rich history of recrimination—and lots of other names! Because of its association with Columbus, who sailed under Spanish flag, Europeans called it the Spanish disease. The French called syphilis the Neapolitan or Italian disease, because they caught it from residents of Naples, home of a major outbreak. The Russians called it a Polish disease. The Polish called it a Russian disease. The Turks called it a Christian disease. The English called syphilis the French Pox.

"¢ Syphilis was quite common in Shakespeare's England, and his characters often used it as a curse: "A pox o' your throat, you bawling, blasphemous, uncharitable dog!" (The Tempest 1.1.21) or "A pox of your houses" (Romeo and Juliet 3.1.60).

"¢ The conventional treatment for several hundred years was to inhale mercury vapor, which did kill the spirochete that causes syphilis—but it also poisoned the patient.

tuskegee.jpg"¢ From 1932 to 1972, the U.S. Public Health Service conducted the infamous Tuskegee syphilis study in rural Alabama. The idea was to examine the effects of untreated syphilis in 600 African-American men. But in the process, according to the CDC, the men were "never given adequate treatment for their disease." Some of the men weren't even told they had syphilis! The resulting investigation led to laws requiring that patients give their informed consent to participate in a study, but only after researchers must provide certain information to participants before a study begins. This principle now guides medical studies nationwide.

Coming Tomorrow: The Plague.

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10 Things We Know About The Handmaid’s Tale Season 2
Hulu
Hulu

Though Hulu has been producing original content for more than five years now, 2017 turned out to be a banner year for the streaming network with the debut of The Handmaid’s Tale on April 26, 2017. The dystopian drama, based on Margaret Atwood’s 1985 book, imagines a future in which a theocratic regime known as Gilead has taken over the United States and enslaved fertile women so that the group’s most powerful couples can procreate.

If it all sounds rather bleak, that’s because it is—but it’s also one of the most impressive new series to arrive in years (as evidenced by the slew of awards it has won, including eight Emmy and two Golden Globe Awards). Fortunately, fans left wanting more don’t have that much longer to wait, as season two will premiere on Hulu in April. In the meantime, here’s everything we know about The Handmaid’s Tale’s second season.

1. IT WILL PREMIERE WITH TWO EPISODES.

When The Handmaid’s Tale returns on April 25, 2018, Hulu will release the first two of its 13 new episodes on premiere night, then drop another new episode every Wednesday.

2. MARGARET ATWOOD WILL CONTINUE TO HELP SHAPE THE NARRATIVE.

Fans of Atwood’s novel who didn’t like that season one went beyond the original source material are in for some more disappointment in season two, as the narrative will again go beyond the scope of what Atwood covered. But creator/showrunner Bruce Miller doesn’t necessarily agree with the criticism they received in season one.

“People talk about how we're beyond the book, but we're not really," Miller told Newsweek. "The book starts, then jumps 200 years with an academic discussion at the end of it, about what's happened in those intervening 200 years. We're not going beyond the novel. We're just covering territory [Atwood] covered quickly, a bit more slowly.”

Even more importantly, Miller's got Atwood on his side. The author serves as a consulting producer on the show, and the title isn’t an honorary one. For Miller, Atwood’s input is essential to shaping the show, particularly as it veers off into new territories. And they were already thinking about season two while shooting season one. “Margaret and I had started to talk about the shape of season two halfway through the first [season],” he told Entertainment Weekly.

In fact, Miller said that when he first began working on the show, he sketched out a full 10 seasons worth of storylines. “That’s what you have to do when you’re taking on a project like this,” he said.

3. MOTHERHOOD WILL BE A CENTRAL THEME.

As with season one, motherhood is a key theme in the series. And June/Offred’s pregnancy will be one of the main plotlines. “So much of [Season 2] is about motherhood,” Elisabeth Moss said during the Television Critics Association press tour. “Bruce and I always talked about the impending birth of this child that’s growing inside her as a bit of a ticking time bomb, and the complications of that are really wonderful to explore. It’s a wonderful thing to have a baby, but she’s having it potentially in this world that she may not want to bring it into. And then, you know, if she does have the baby, the baby gets taken away from her and she can’t be its mother. So, obviously, it’s very complicated and makes for good drama. But, it’s a very big part of this season, and it gets bigger and bigger as the show goes on.”

4. THE RESISTANCE IS COMING.

Just because June is pregnant, don’t expect her to sit on the sidelines as the resistance to Gilead continues. “There is more than one way to resist," Moss said. “There is resistance within [June], and that is a big part of this season.”

5. WE’LL GET TO SEE THE COLONIES.

A scene from 'The Handmaid's Tale'
Hulu

Miller, understandably, isn’t eager to share too many details about the new season. “I’m not being cagey!” he swore to Entertainment Weekly. “I just want the viewers to experience it for themselves!” What he did confirm is that the new season will bring us to the colonies—reportedly in episode two—and show what life is like for those who have been sent there.

It will also delve further into what life is like for the refugees who managed to escape Gilead, like Luke and Moira.

6. MARISA TOMEI WILL APPEAR IN AN EPISODE.

Though she won’t be a regular cast member, Miller recently announced that Oscar winner Marisa Tomei will make a guest appearance in the new season’s second episode. Yes, the one that will show us the Colonies. In fact, that’s where we’ll meet her; Tomei is playing the wife of a Commander.

7. WE’LL LEARN MORE ABOUT THE ORIGINS OF GILEAD.

As a group shrouded in secrecy, we still don’t know much about how and where Gilead began. That will change a bit in season two. When discussing some of the questions viewers will have answered, executive producer Warren Littlefield promised that, "How did Gilead come about? How did this happen?” would be two of them. “We get to follow the historical creation of this world,” he said.

8. THERE WILL BE AT LEAST ONE HANDMAID FUNERAL.

A scene from 'The Handmaid's Tale'
Hulu

While Miller wouldn’t talk about who the handmaids are mourning in a teaser shot from season two that shows a handmaid’s funeral, he was excited to talk about creating the look for the scene. “Everything from the design of their costumes to the way they look is so chilling,” Miller told Entertainment Weekly. “These scenes that are so beautiful, while set in such a terrible place, provide the kind of contrast that makes me happy.”

9. ELISABETH MOSS SAYS THE TONE WILL BE DARKER.

Like season one, Miller says that The Handmaid’s Tale's second season will again balance its darker, dystopian themes with glimpses of hopefulness. “I think the first season had very difficult things, and very hopeful things, and I think this season is exactly the same way,” he told the Los Angeles Times. “There come some surprising moments of real hope and victory, and strength, that come from surprising places.”

Moss, however, has a different opinion. “It's a dark season,” she told reporters at TCA. “I would say arguably it's darker than Season 1—if that's possible.”

10. IT WILL ALSO BE BLOODIER.

A scene from 'The Handmaid's Tale'
Hulu

When pressed about how the teaser images for the new season seemed to feature a lot of blood, Miller conceded: “Oh gosh, yeah. There may be a little more blood this season.”

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NUS Environmental Research Institute, Subnero
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Researchers in Singapore Deploy Robot Swans to Test Water Quality
NUS Environmental Research Institute, Subnero
NUS Environmental Research Institute, Subnero

There's something peculiar about the new swans floating around reservoirs in Singapore. They drift across the water like normal birds, but upon closer inspection, onlookers will find they're not birds at all: They're cleverly disguised robots designed to test the quality of the city's water.

As Dezeen reports, the high-tech waterfowl, dubbed NUSwan (New Smart Water Assessment Network), are the work of researchers at the National University of Singapore [PDF]. The team invented the devices as a way to tackle the challenges of maintaining an urban water source. "Water bodies are exposed to varying sources of pollutants from urban run-offs and industries," they write in a statement. "Several methods and protocols in monitoring pollutants are already in place. However, the boundaries of extensive assessment for the water bodies are limited by labor intensive and resource exhaustive methods."

By building water assessment technology into a plastic swan, they're able to analyze the quality of the reservoirs cheaply and discreetly. Sensors on the robots' undersides measure factors like dissolved oxygen and chlorophyll levels. The swans wirelessly transmit whatever data they collect to the command center on land, and based on what they send, human pilots can remotely tweak the robots' performance in real time. The hope is that the simple, adaptable technology will allow researchers to take smarter samples and better understand the impact of the reservoir's micro-ecosystem on water quality.

Man placing robotic swan in water.
NUS Environmental Research Institute, Subnero

This isn't the first time humans have used robots disguised as animals as tools for studying nature. Check out this clip from the BBC series Spy in the Wild for an idea of just how realistic these robots can get.

[h/t Dezeen]

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